SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jz3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_2
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3jz3 SENSOR PROTEIN QSEC
(Escherichia
coli) 		3 / 3 LEU A 299
HIS A 429
ILE A 425
 None
 0.52A 1s9pB-3jz3A:
undetectable		 1s9pB-3jz3A:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_1
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 3jz3 SENSOR PROTEIN QSEC
(Escherichia
coli) 		3 / 3 SER A 354
ASP A 362
ASP A 323
 None
 0.71A 2plwA-3jz3A:
undetectable		 2plwA-3jz3A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCY_A_DB8A401_2
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 3jz3 SENSOR PROTEIN QSEC
(Escherichia
coli) 		4 / 4 VAL A 308
LEU A 352
ASN A 304
ASP A 303
 None
 1.02A 5vcyA-3jz3A:
undetectable		 5vcyA-3jz3A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_1
(ADENOSYLHOMOCYSTEINA
SE)		 3jz3 SENSOR PROTEIN QSEC
(Escherichia
coli) 		5 / 12 LEU A 356
HIS A 429
LEU A 302
GLY A 430
PHE A 383
 None
 1.48A 6aphA-3jz3A:
undetectable		 6aphA-3jz3A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_A_ECLA1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 3jz3 SENSOR PROTEIN QSEC
(Escherichia
coli) 		4 / 7 ILE A 384
PHE A 435
ILE A 344
ALA A 426
 None
 0.87A 6b5vA-3jz3A:
undetectable
6b5vC-3jz3A:
undetectable		 6b5vA-3jz3A:
19.76
6b5vC-3jz3A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_C_ECLC1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 3jz3 SENSOR PROTEIN QSEC
(Escherichia
coli) 		4 / 7 ILE A 384
PHE A 435
ILE A 344
ALA A 426
 None
 0.87A 6b5vC-3jz3A:
undetectable
6b5vD-3jz3A:
undetectable		 6b5vC-3jz3A:
19.76
6b5vD-3jz3A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_D_ECLD1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 3jz3 SENSOR PROTEIN QSEC
(Escherichia
coli) 		4 / 7 ALA A 426
ILE A 384
PHE A 435
ILE A 344
 None
 0.88A 6b5vB-3jz3A:
undetectable
6b5vD-3jz3A:
undetectable		 6b5vB-3jz3A:
19.76
6b5vD-3jz3A:
19.76