SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jza'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Y7I_A_SALA502_1 (SALICYLIC ACID-BINDING PROTEIN 2)	3jza	UNCHARACTERIZED PROTEIN DRRA (Legionella pneumophila)	3 / 3	LEU B 493 HIS B 496 LYS B 497	None	1.09A	1y7iA-3jzaB: undetectable	1y7iA-3jzaB: 23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YOE_C_FL7C1318_1 (CYS-LOOP LIGAND-GATED ION CHANNEL)	3jza	UNCHARACTERIZED PROTEIN DRRA (Legionella pneumophila)	4 / 8	ASN B 437 GLY B 411 ILE B 398 SER B 408	None	0.80A	2yoeB-3jzaB: undetectable 2yoeC-3jzaB: undetectable	2yoeB-3jzaB: 20.07 2yoeC-3jzaB: 20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EKY_A_DR7A100_2 (PROTEASE)	3jza	UNCHARACTERIZED PROTEIN DRRA (Legionella pneumophila)	5 / 9	ILE B 498 GLY B 470 ILE B 365 VAL B 478 ILE B 475	None	1.28A	3ekyB-3jzaB: undetectable	3ekyB-3jzaB: 19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XT8_A_TMQA302_1 (RV2671)	3jza	UNCHARACTERIZED PROTEIN DRRA (Legionella pneumophila)	5 / 12	SER B 399 GLY B 402 ALA B 404 PHE B 460 GLU B 361	None	1.22A	4xt8A-3jzaB: undetectable	4xt8A-3jzaB: 21.64

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1Y7I_A_SALA502_1","SALICYLIC ACID-BINDING PROTEIN 2","3jza","UNCHARACTERIZED PROTEIN DRRA","Legionella pneumophila",3,"LEU B 493;HIS B 496;LYS B 497","None","1.09A","1y7iA-3jzaB:undetectable","1y7iA-3jzaB:23.77"],["2YOE_C_FL7C1318_1","CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL","3jza","UNCHARACTERIZED PROTEIN DRRA","Legionella pneumophila",4,"ASN B 437;GLY B 411;ILE B 398;SER B 408","None","0.80A","2yoeB-3jzaB:undetectable;2yoeC-3jzaB:undetectable","2yoeB-3jzaB:20.07;2yoeC-3jzaB:20.07"],["3EKY_A_DR7A100_2","PROTEASE;PROTEASE","3jza","UNCHARACTERIZED PROTEIN DRRA","Legionella pneumophila",5,"ILE B 498;GLY B 470;ILE B 365;VAL B 478;ILE B 475","None","1.28A","3ekyB-3jzaB:undetectable","3ekyB-3jzaB:19.27"],["4XT8_A_TMQA302_1","RV2671","3jza","UNCHARACTERIZED PROTEIN DRRA","Legionella pneumophila",5,"SER B 399;GLY B 402;ALA B 404;PHE B 460;GLU B 361","None","1.22A","4xt8A-3jzaB:undetectable","4xt8A-3jzaB:21.64"]]