SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jzl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_1
(PROTEIN (ADENOSINE
KINASE))		 3jzl PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
monocytogenes) 		5 / 12 ASN A 227
GLY A 231
GLY A 230
ALA A 286
LEU A 315
 LLP  A 226 ( 4.6A)
None
None
None
None
 0.92A 1bx4A-3jzlA:
undetectable		 1bx4A-3jzlA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OHR_A_1UNA201_2
(ASPARTYLPROTEASE)		 3jzl PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
monocytogenes) 		5 / 9 LEU A 114
GLY A  95
ILE A  96
VAL A 118
ILE A 117
 None
 0.89A 1ohrB-3jzlA:
undetectable		 1ohrB-3jzlA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VM1_A_TAZA504_1
(BETA-LACTAMASE SHV-1)		 3jzl PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
monocytogenes) 		3 / 3 ASP A 357
TYR A 350
GLU A 355
 None
 0.82A 1vm1A-3jzlA:
undetectable		 1vm1A-3jzlA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CBR_A_A80A201_1
(PROTEIN (CRABP-I))		 3jzl PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
monocytogenes) 		5 / 12 PHE A  71
VAL A  78
LEU A  63
VAL A  66
GLY A 229
 None
None
None
None
LLP  A 226 ( 3.6A)
 1.07A 2cbrA-3jzlA:
undetectable		 2cbrA-3jzlA:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 3jzl PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
monocytogenes) 		5 / 12 LEU A 114
GLY A  95
ILE A  96
VAL A 118
ILE A 117
 None
 0.87A 2q63A-3jzlA:
undetectable		 2q63A-3jzlA:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_1
(PROTEASE
(RETROPEPSIN))		 3jzl PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
monocytogenes) 		5 / 12 LEU A 114
GLY A  95
ILE A  96
VAL A 118
ILE A 117
 None
 0.85A 3bvbA-3jzlA:
undetectable		 3bvbA-3jzlA:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DOU_A_SAMA1_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 3jzl PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
monocytogenes) 		5 / 12 ALA A 286
GLY A 230
GLY A 390
LEU A 224
ALA A 279
 None
 0.83A 3douA-3jzlA:
undetectable		 3douA-3jzlA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_D_BRLD478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3jzl PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
monocytogenes) 		4 / 4 ILE A 106
GLN A 165
ILE A 185
LEU A 114
 None
LLP  A 226 ( 4.1A)
None
None
 1.31A 3dzyD-3jzlA:
undetectable		 3dzyD-3jzlA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_1
(GAG-POL POLYPROTEIN)		 3jzl PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
monocytogenes) 		5 / 12 LEU A 114
GLY A  95
ILE A  96
VAL A 118
ILE A 117
 None
 0.88A 3jw2A-3jzlA:
undetectable		 3jw2A-3jzlA:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_1
(HIV-1 PROTEASE)		 3jzl PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
monocytogenes) 		5 / 12 LEU A 114
GLY A  95
ILE A  96
VAL A 118
ILE A 117
 None
 0.85A 3k4vA-3jzlA:
undetectable		 3k4vA-3jzlA:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9W_A_ACTA170_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3jzl PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
monocytogenes) 		3 / 3 SER A  84
GLY A  85
THR A  86
 LLP  A 226 ( 3.3A)
LLP  A 226 ( 3.5A)
LLP  A 226 ( 3.4A)
 0.03A 3k9wA-3jzlA:
undetectable		 3k9wA-3jzlA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_1
(PROTEASE)		 3jzl PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
monocytogenes) 		5 / 12 LEU A 114
GLY A  95
ILE A  96
VAL A 118
ILE A 117
 None
 0.86A 3ndtA-3jzlA:
undetectable		 3ndtA-3jzlA:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_3
(PROTEASE)		 3jzl PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
monocytogenes) 		5 / 12 LEU A 114
GLY A  95
ILE A  96
VAL A 118
ILE A 117
 None
 0.89A 3ndtB-3jzlA:
undetectable		 3ndtB-3jzlA:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_B_017B200_2
(FIV PROTEASE)		 3jzl PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
monocytogenes) 		5 / 9 GLY A 216
ALA A 217
ASP A 218
ILE A 219
MET A 161
 None
 0.98A 3ogpB-3jzlA:
undetectable		 3ogpB-3jzlA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGQ_A_AB1A200_2
(FIV PROTEASE)		 3jzl PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
monocytogenes) 		5 / 12 GLY A 216
ALA A 217
ASP A 218
ILE A 219
MET A 161
 None
 0.80A 3ogqB-3jzlA:
undetectable		 3ogqB-3jzlA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWW_A_ROCA1001_2
(ENDOTHIAPEPSIN)		 3jzl PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
monocytogenes) 		4 / 8 SER A 167
SER A 370
ASP A 200
THR A  86
 LLP  A 226 ( 4.1A)
LLP  A 226 ( 3.0A)
LLP  A 226 ( 2.8A)
LLP  A 226 ( 3.4A)
 0.78A 3pwwA-3jzlA:
undetectable		 3pwwA-3jzlA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQF_B_017B101_1
(ASPARTYL PROTEASE)		 3jzl PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
monocytogenes) 		5 / 12 LEU A 114
GLY A  95
ILE A  96
VAL A 118
ILE A 117
 None
 0.83A 4dqfA-3jzlA:
undetectable		 4dqfA-3jzlA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_3
(HIV-1 PROTEASE)		 3jzl PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
monocytogenes) 		3 / 3 ASP A 200
LEU A  93
VAL A 246
 LLP  A 226 ( 2.8A)
None
None
 0.71A 4jecB-3jzlA:
undetectable		 4jecB-3jzlA:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QGI_A_ROCA101_2
(PROTEASE)		 3jzl PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
monocytogenes) 		5 / 11 LEU A 114
GLY A  95
ILE A  96
VAL A 118
ILE A 117
 None
 0.93A 4qgiB-3jzlA:
undetectable		 4qgiB-3jzlA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J2T_C_VLBC503_2
(TUBULIN ALPHA-1B
CHAIN)		 3jzl PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
monocytogenes) 		6 / 12 VAL A 199
ILE A 220
ALA A 221
PHE A  71
GLY A 216
ILE A 185
 None
 1.31A 5j2tC-3jzlA:
4.0		 5j2tC-3jzlA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR1_B_017B101_1
(PROTEASE PR5-DRV)		 3jzl PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
monocytogenes) 		5 / 10 LEU A 114
GLY A  95
ILE A  96
VAL A 118
ILE A 117
 None
 0.85A 5kr1A-3jzlA:
undetectable		 5kr1A-3jzlA:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_2
(PROTEASE PR5-SQV)		 3jzl PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
monocytogenes) 		5 / 9 LEU A 114
GLY A  95
ILE A  96
VAL A 118
ILE A 117
 None
 1.06A 5kr2D-3jzlA:
undetectable		 5kr2D-3jzlA:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 3jzl PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
monocytogenes) 		5 / 10 ILE A 164
ILE A 219
ALA A 221
ILE A 220
ILE A  89
 None
 1.04A 5mvmD-3jzlA:
undetectable
5mvmE-3jzlA:
undetectable		 5mvmD-3jzlA:
11.33
5mvmE-3jzlA:
11.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYC_A_1YNA502_1
(PROTEIN CYP51)		 3jzl PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
monocytogenes) 		5 / 12 PHE A 206
ALA A 279
ALA A 262
ALA A 264
LEU A 269
 None
 1.33A 6aycA-3jzlA:
undetectable		 6aycA-3jzlA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCX_A_ZMRA519_0
(NEURAMINIDASE)		 3jzl PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
monocytogenes) 		5 / 12 ARG A  79
GLU A  64
ASP A  61
ARG A  65
GLU A 243
 None
 1.36A 6hcxA-3jzlA:
undetectable		 6hcxA-3jzlA:
10.75