SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3k0b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3k0b PREDICTED
N6-ADENINE-SPECIFIC
DNA METHYLASE
(Listeria
monocytogenes) 		5 / 12 LEU A 160
GLY A 159
ALA A 158
PRO A 217
PHE A 219
 None
EDO  A 601 (-3.8A)
EDO  A 601 ( 4.2A)
None
None
 1.08A 1eqbA-3k0bA:
undetectable		 1eqbA-3k0bA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_A_URFA1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 3k0b PREDICTED
N6-ADENINE-SPECIFIC
DNA METHYLASE
(Listeria
monocytogenes) 		4 / 6 ILE A  45
ASN A  49
SER A 156
THR A   9
 None
None
None
GOL  A 701 (-2.6A)
 1.00A 1h7xA-3k0bA:
3.8		 1h7xA-3k0bA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_B_URFB1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 3k0b PREDICTED
N6-ADENINE-SPECIFIC
DNA METHYLASE
(Listeria
monocytogenes) 		4 / 6 ILE A  45
ASN A  49
SER A 156
THR A   9
 None
None
None
GOL  A 701 (-2.6A)
 1.02A 1h7xB-3k0bA:
4.2		 1h7xB-3k0bA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_C_URFC1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 3k0b PREDICTED
N6-ADENINE-SPECIFIC
DNA METHYLASE
(Listeria
monocytogenes) 		4 / 6 ILE A  45
ASN A  49
SER A 156
THR A   9
 None
None
None
GOL  A 701 (-2.6A)
 1.01A 1h7xC-3k0bA:
3.1		 1h7xC-3k0bA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_D_URFD1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 3k0b PREDICTED
N6-ADENINE-SPECIFIC
DNA METHYLASE
(Listeria
monocytogenes) 		4 / 6 ILE A  45
ASN A  49
SER A 156
THR A   9
 None
None
None
GOL  A 701 (-2.6A)
 1.02A 1h7xD-3k0bA:
4.9		 1h7xD-3k0bA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IJ7_C_TPFC2471_1
(CYTOCHROME P450 121)		 3k0b PREDICTED
N6-ADENINE-SPECIFIC
DNA METHYLASE
(Listeria
monocytogenes) 		4 / 8 THR A 186
VAL A 337
ASN A 303
PHE A 194
 None
 1.09A 2ij7C-3k0bA:
undetectable		 2ij7C-3k0bA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBN_A_CAMA442_0
(CYTOCHROME P450-CAM)		 3k0b PREDICTED
N6-ADENINE-SPECIFIC
DNA METHYLASE
(Listeria
monocytogenes) 		4 / 7 THR A 293
VAL A 326
VAL A 300
VAL A 335
 None
 0.85A 2qbnA-3k0bA:
undetectable		 2qbnA-3k0bA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN8_A_DEXA247_2
(GLUCOCORTICOID
RECEPTOR 2)		 3k0b PREDICTED
N6-ADENINE-SPECIFIC
DNA METHYLASE
(Listeria
monocytogenes) 		3 / 3 MET A   1
MET A 231
PHE A  -2
 None
 1.38A 3gn8A-3k0bA:
undetectable		 3gn8A-3k0bA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECLA600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3k0b PREDICTED
N6-ADENINE-SPECIFIC
DNA METHYLASE
(Listeria
monocytogenes) 		4 / 8 LEU A 185
THR A 186
ALA A 302
ILE A 174
 None
 0.72A 3jusA-3k0bA:
undetectable		 3jusA-3k0bA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3k0b PREDICTED
N6-ADENINE-SPECIFIC
DNA METHYLASE
(Listeria
monocytogenes) 		4 / 8 LEU A 185
THR A 186
ALA A 302
ILE A 174
 None
 0.72A 3jusA-3k0bA:
undetectable		 3jusA-3k0bA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA309_1
(BETA-LACTAMASE)		 3k0b PREDICTED
N6-ADENINE-SPECIFIC
DNA METHYLASE
(Listeria
monocytogenes) 		4 / 5 ILE A  17
ARG A 163
THR A 177
GLU A 207
 None
 1.49A 3ny4A-3k0bA:
undetectable		 3ny4A-3k0bA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_A_SAMA801_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 3k0b PREDICTED
N6-ADENINE-SPECIFIC
DNA METHYLASE
(Listeria
monocytogenes) 		5 / 12 GLY A 200
SER A 201
ASP A 261
VAL A 288
LEU A 319
 None
 0.76A 3v8vA-3k0bA:
40.6		 3v8vA-3k0bA:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_A_SAMA801_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 3k0b PREDICTED
N6-ADENINE-SPECIFIC
DNA METHYLASE
(Listeria
monocytogenes) 		5 / 12 GLY A 200
SER A 201
VAL A 288
ASN A 303
LEU A 319
 None
 1.03A 3v8vA-3k0bA:
40.6		 3v8vA-3k0bA:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_A_SAMA801_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 3k0b PREDICTED
N6-ADENINE-SPECIFIC
DNA METHYLASE
(Listeria
monocytogenes) 		5 / 12 GLY A 200
SER A 201
VAL A 288
PRO A 304
LEU A 319
 None
 1.21A 3v8vA-3k0bA:
40.6		 3v8vA-3k0bA:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_A_SAMA801_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 3k0b PREDICTED
N6-ADENINE-SPECIFIC
DNA METHYLASE
(Listeria
monocytogenes) 		6 / 12 ILE A 174
GLY A 200
SER A 201
THR A 203
VAL A 288
ASN A 303
 None
 0.91A 3v8vA-3k0bA:
40.6		 3v8vA-3k0bA:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_A_SAMA801_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 3k0b PREDICTED
N6-ADENINE-SPECIFIC
DNA METHYLASE
(Listeria
monocytogenes) 		5 / 12 PRO A 173
GLY A 200
SER A 201
VAL A 288
PRO A 304
 None
 1.15A 3v8vA-3k0bA:
40.6		 3v8vA-3k0bA:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_A_SAMA801_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 3k0b PREDICTED
N6-ADENINE-SPECIFIC
DNA METHYLASE
(Listeria
monocytogenes) 		7 / 12 PRO A 173
ILE A 174
GLY A 200
SER A 201
THR A 203
ASP A 261
VAL A 288
 None
 0.98A 3v8vA-3k0bA:
40.6		 3v8vA-3k0bA:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_B_SAMB801_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 3k0b PREDICTED
N6-ADENINE-SPECIFIC
DNA METHYLASE
(Listeria
monocytogenes) 		5 / 11 GLY A 200
ASP A 259
ASP A 261
VAL A 288
LEU A 319
 None
 0.72A 3v8vB-3k0bA:
36.0		 3v8vB-3k0bA:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_B_SAMB801_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 3k0b PREDICTED
N6-ADENINE-SPECIFIC
DNA METHYLASE
(Listeria
monocytogenes) 		5 / 11 GLY A 200
ASP A 259
VAL A 288
ASN A 303
LEU A 319
 None
 0.98A 3v8vB-3k0bA:
36.0		 3v8vB-3k0bA:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_B_SAMB801_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 3k0b PREDICTED
N6-ADENINE-SPECIFIC
DNA METHYLASE
(Listeria
monocytogenes) 		5 / 11 GLY A 200
ASP A 259
VAL A 288
PRO A 304
LEU A 319
 None
 1.20A 3v8vB-3k0bA:
36.0		 3v8vB-3k0bA:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DCM_A_SAMA401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE G)		 3k0b PREDICTED
N6-ADENINE-SPECIFIC
DNA METHYLASE
(Listeria
monocytogenes) 		5 / 11 ASP A 196
GLY A 200
ILE A 204
ASP A 259
ASN A 303
 None
 0.91A 4dcmA-3k0bA:
14.5		 4dcmA-3k0bA:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_F_ASWF101_1
(DNA TOPOISOMERASE
2-BETA)		 3k0b PREDICTED
N6-ADENINE-SPECIFIC
DNA METHYLASE
(Listeria
monocytogenes) 		4 / 6 ARG A 166
GLY A 200
ALA A 179
GLN A 270
 None
 1.14A 4g0uA-3k0bA:
undetectable		 4g0uA-3k0bA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_A_SVRA301_1
(NUCLEOCAPSID PROTEIN)		 3k0b PREDICTED
N6-ADENINE-SPECIFIC
DNA METHYLASE
(Listeria
monocytogenes) 		5 / 11 GLY A 200
ALA A 272
GLN A 169
PRO A 305
ILE A 174
 None
 1.38A 4j4vA-3k0bA:
undetectable		 4j4vA-3k0bA:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_D_SVRD301_1
(NUCLEOCAPSID PROTEIN)		 3k0b PREDICTED
N6-ADENINE-SPECIFIC
DNA METHYLASE
(Listeria
monocytogenes) 		5 / 11 GLY A 200
ALA A 272
GLN A 169
PRO A 305
ILE A 174
 None
 1.46A 4j4vD-3k0bA:
undetectable
4j4vE-3k0bA:
undetectable		 4j4vD-3k0bA:
23.34
4j4vE-3k0bA:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 3k0b PREDICTED
N6-ADENINE-SPECIFIC
DNA METHYLASE
(Listeria
monocytogenes) 		5 / 9 TRP A  51
PHE A 223
SER A 225
ALA A  48
ALA A 209
 None
 1.40A 4l6va-3k0bA:
undetectable
4l6vf-3k0bA:
undetectable		 4l6va-3k0bA:
18.62
4l6vf-3k0bA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_B_VORB590_1
(14-ALPHA STEROL
DEMETHYLASE)		 3k0b PREDICTED
N6-ADENINE-SPECIFIC
DNA METHYLASE
(Listeria
monocytogenes) 		4 / 7 TYR A 195
ALA A 289
ILE A 260
LEU A 319
 None
 1.00A 4uymB-3k0bA:
undetectable		 4uymB-3k0bA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZO1_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)		 3k0b PREDICTED
N6-ADENINE-SPECIFIC
DNA METHYLASE
(Listeria
monocytogenes) 		5 / 12 ILE A  45
ALA A  48
ALA A 239
ASN A  49
PHE A   4
 None
 1.48A 4zo1X-3k0bA:
undetectable		 4zo1X-3k0bA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CU6_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3k0b PREDICTED
N6-ADENINE-SPECIFIC
DNA METHYLASE
(Listeria
monocytogenes) 		4 / 6 TYR A 336
ILE A 204
ASP A 196
PRO A 197
 None
 0.80A 5cu6A-3k0bA:
undetectable		 5cu6A-3k0bA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 3k0b PREDICTED
N6-ADENINE-SPECIFIC
DNA METHYLASE
(Listeria
monocytogenes) 		3 / 3 ALA A  46
ASN A  49
LEU A  50
 None
 0.51A 5i1nC-3k0bA:
undetectable		 5i1nC-3k0bA:
8.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IFT_A_SAMA301_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A)		 3k0b PREDICTED
N6-ADENINE-SPECIFIC
DNA METHYLASE
(Listeria
monocytogenes) 		5 / 12 GLY A 200
ILE A 260
ASP A 261
LEU A 264
VAL A 288
 None
 0.87A 6iftA-3k0bA:
11.9		 6iftA-3k0bA:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NCS_A_ACTA303_0
(N-ACETYLNEURAMINIC
ACID (SIALIC ACID)
SYNTHETASE)		 3k0b PREDICTED
N6-ADENINE-SPECIFIC
DNA METHYLASE
(Listeria
monocytogenes) 		3 / 3 ILE A 281
THR A 282
PRO A 205
 None
 0.27A 6ncsA-3k0bA:
undetectable		 6ncsA-3k0bA:
22.88