SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3k0t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_A_BEZA501_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3k0t ENDORIBONUCLEASE
L-PSP, PUTATIVE
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 TYR A  18
ILE A  34
PRO A 112
GLU A 118
 BGC  A 127 (-3.1A)
BGC  A 127 (-4.0A)
None
BGC  A 127 (-3.5A)
 0.61A 1oniA-3k0tA:
23.1
1oniB-3k0tA:
23.1		 1oniA-3k0tA:
40.94
1oniB-3k0tA:
40.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_B_BEZB503_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3k0t ENDORIBONUCLEASE
L-PSP, PUTATIVE
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 6 TYR A  18
ILE A  34
PRO A 112
GLU A 118
 BGC  A 127 (-3.1A)
BGC  A 127 (-4.0A)
None
BGC  A 127 (-3.5A)
 0.56A 1oniB-3k0tA:
23.1
1oniC-3k0tA:
23.3		 1oniB-3k0tA:
40.94
1oniC-3k0tA:
40.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_C_BEZC505_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3k0t ENDORIBONUCLEASE
L-PSP, PUTATIVE
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 6 TYR A  18
ILE A  34
PRO A 112
GLU A 118
 BGC  A 127 (-3.1A)
BGC  A 127 (-4.0A)
None
BGC  A 127 (-3.5A)
 0.31A 1oniA-3k0tA:
23.1
1oniC-3k0tA:
23.3		 1oniA-3k0tA:
40.94
1oniC-3k0tA:
40.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_E_BEZE509_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3k0t ENDORIBONUCLEASE
L-PSP, PUTATIVE
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 TYR A  18
ILE A  34
PRO A 112
GLU A 118
 BGC  A 127 (-3.1A)
BGC  A 127 (-4.0A)
None
BGC  A 127 (-3.5A)
 0.47A 1oniD-3k0tA:
23.3
1oniE-3k0tA:
23.4		 1oniD-3k0tA:
40.94
1oniE-3k0tA:
40.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_I_BEZI517_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3k0t ENDORIBONUCLEASE
L-PSP, PUTATIVE
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 TYR A  18
ILE A  34
PRO A 112
GLU A 118
 BGC  A 127 (-3.1A)
BGC  A 127 (-4.0A)
None
BGC  A 127 (-3.5A)
 0.63A 1oniG-3k0tA:
23.1
1oniI-3k0tA:
23.0		 1oniG-3k0tA:
40.94
1oniI-3k0tA:
40.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOF_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 3k0t ENDORIBONUCLEASE
L-PSP, PUTATIVE
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 5 LEU A 123
ASP A  71
ALA A  65
ILE A 125
 None
 1.05A 2aofB-3k0tA:
undetectable		 2aofB-3k0tA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_A_FUAA2002_1
(SERUM ALBUMIN)		 3k0t ENDORIBONUCLEASE
L-PSP, PUTATIVE
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 9 ILE A  51
ALA A 115
VAL A 117
GLU A 118
 None
None
None
BGC  A 127 (-3.5A)
 0.86A 2vufA-3k0tA:
undetectable		 2vufA-3k0tA:
13.11