SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3k0x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KF6_B_ACTB704_0 (FUMARATE REDUCTASE FLAVOPROTEIN FUMARATE REDUCTASE IRON-SULFUR PROTEIN)	3k0x	PROTEIN TEN1 (Schizosaccharomy ces pombe)	3 / 3	ARG A 92 GLY A 40 ASP A 39	None	0.44A	1kf6A-3k0xA: undetectable 1kf6B-3k0xA: undetectable	1kf6A-3k0xA: 9.68 1kf6B-3k0xA: 14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RV5_C_DXCC92_0 (TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES)	3k0x	PROTEIN TEN1 (Schizosaccharomy ces pombe)	4 / 4	VAL A 66 PHE A 23 PHE A 8 VAL A 95	None	1.21A	3rv5C-3k0xA: undetectable 3rv5D-3k0xA: undetectable	3rv5C-3k0xA: 20.39 3rv5D-3k0xA: 20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LNW_A_T3A501_2 (THYROID HORMONE RECEPTOR ALPHA)	3k0x	PROTEIN TEN1 (Schizosaccharomy ces pombe)	3 / 3	ILE A 86 MET A 94 ARG A 98	None	0.70A	4lnwA-3k0xA: undetectable	4lnwA-3k0xA: 14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LNX_A_T3A502_2 (THYROID HORMONE RECEPTOR ALPHA)	3k0x	PROTEIN TEN1 (Schizosaccharomy ces pombe)	3 / 3	ILE A 86 MET A 94 ARG A 98	None	0.72A	4lnxA-3k0xA: undetectable	4lnxA-3k0xA: 14.39

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1KF6_B_ACTB704_0","FUMARATE REDUCTASE FLAVOPROTEIN;FUMARATE REDUCTASE IRON-SULFUR PROTEIN","3k0x","PROTEIN TEN1","Schizosaccharomyces pombe",3,"ARG A  92;GLY A  40;ASP A  39","None","0.44A","1kf6A-3k0xA:undetectable;1kf6B-3k0xA:undetectable","1kf6A-3k0xA:9.68;1kf6B-3k0xA:14.63"],["3RV5_C_DXCC92_0","TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES","3k0x","PROTEIN TEN1","Schizosaccharomyces pombe",4,"VAL A  66;PHE A  23;PHE A   8;VAL A  95","None","1.21A","3rv5C-3k0xA:undetectable;3rv5D-3k0xA:undetectable","3rv5C-3k0xA:20.39;3rv5D-3k0xA:20.39"],["4LNW_A_T3A501_2","THYROID HORMONE RECEPTOR ALPHA","3k0x","PROTEIN TEN1","Schizosaccharomyces pombe",3,"ILE A  86;MET A  94;ARG A  98","None","0.70A","4lnwA-3k0xA:undetectable","4lnwA-3k0xA:14.39"],["4LNX_A_T3A502_2","THYROID HORMONE RECEPTOR ALPHA","3k0x","PROTEIN TEN1","Schizosaccharomyces pombe",3,"ILE A  86;MET A  94;ARG A  98","None","0.72A","4lnxA-3k0xA:undetectable","4lnxA-3k0xA:14.39"]]