SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3k0y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_F_TFPF201_1
(PROTEIN S100-A4)		 3k0y PUTATIVE TOXIN
RELATED PROTEIN
(Parabacteroides
distasonis) 		4 / 5 MET A 137
PHE A 148
PHE A 176
PHE A 195
 None
 1.38A 3ko0F-3k0yA:
undetectable
3ko0G-3k0yA:
undetectable		 3ko0F-3k0yA:
15.95
3ko0G-3k0yA:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QJ7_A_SPMA264_1
(THYMIDYLATE SYNTHASE)		 3k0y PUTATIVE TOXIN
RELATED PROTEIN
(Parabacteroides
distasonis) 		4 / 8 LEU A 200
ASP A 202
ASP A 230
TYR A 227
 None
 0.77A 3qj7A-3k0yA:
undetectable
3qj7D-3k0yA:
undetectable		 3qj7A-3k0yA:
19.41
3qj7D-3k0yA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_D_ACTD201_0
(RETINOL-BINDING
PROTEIN 2)		 3k0y PUTATIVE TOXIN
RELATED PROTEIN
(Parabacteroides
distasonis) 		3 / 3 ASP A  58
HIS A  98
LYS A  59
 None
 0.85A 4qzuD-3k0yA:
undetectable		 4qzuD-3k0yA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2S_A_ACTA107_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 3k0y PUTATIVE TOXIN
RELATED PROTEIN
(Parabacteroides
distasonis) 		3 / 3 VAL A  43
THR A  41
ARG A  53
 None
 0.70A 5b2sB-3k0yA:
undetectable		 5b2sB-3k0yA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2T_A_ACTA108_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 3k0y PUTATIVE TOXIN
RELATED PROTEIN
(Parabacteroides
distasonis) 		3 / 3 VAL A  43
THR A  41
ARG A  53
 None
 0.72A 5b2tB-3k0yA:
undetectable		 5b2tB-3k0yA:
10.76