SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3k0z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_1
(ADENOSINE DEAMINASE)		 3k0z PUTATIVE POLYKETIDE
CYCLASE
(Bacillus
cereus) 		5 / 12 HIS A 161
PHE A  62
PHE A  82
ASP A 147
ASP A 159
 None
 1.18A 1a4lD-3k0zA:
undetectable		 1a4lD-3k0zA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_1
(VP39)		 3k0z PUTATIVE POLYKETIDE
CYCLASE
(Bacillus
cereus) 		3 / 3 ASP A  84
ARG A  91
ASP A 147
 None
NHE  A   1 (-3.9A)
None
 0.83A 1vptA-3k0zA:
undetectable		 1vptA-3k0zA:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_1
(2'-O-METHYL
TRANSFERASE)		 3k0z PUTATIVE POLYKETIDE
CYCLASE
(Bacillus
cereus) 		3 / 3 TYR A  63
ASP A  84
ASP A 147
 None
 0.72A 3r24A-3k0zA:
undetectable		 3r24A-3k0zA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_1
(METHYLTRANSFERASE
NSUN4)		 3k0z PUTATIVE POLYKETIDE
CYCLASE
(Bacillus
cereus) 		3 / 3 ASP A  84
ARG A  91
ASP A 147
 None
NHE  A   1 (-3.9A)
None
 0.63A 4fp9D-3k0zA:
undetectable		 4fp9D-3k0zA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_1
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 3k0z PUTATIVE POLYKETIDE
CYCLASE
(Bacillus
cereus) 		3 / 3 ASP A  84
ARG A  91
ASP A 147
 None
NHE  A   1 (-3.9A)
None
 0.71A 4fzvA-3k0zA:
undetectable		 4fzvA-3k0zA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XOY_A_DX4A401_0
(MITOGEN-ACTIVATED
PROTEIN KINASE 1)		 3k0z PUTATIVE POLYKETIDE
CYCLASE
(Bacillus
cereus) 		4 / 6 ALA A  52
LYS A  28
GLN A  49
LEU A  47
 None
 1.00A 4xoyA-3k0zA:
undetectable		 4xoyA-3k0zA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP3_A_DX4A401_0
(MITOGEN-ACTIVATED
PROTEIN KINASE 1)		 3k0z PUTATIVE POLYKETIDE
CYCLASE
(Bacillus
cereus) 		4 / 6 ALA A  52
LYS A  28
GLN A  49
LEU A  47
 None
 1.00A 4xp3A-3k0zA:
undetectable		 4xp3A-3k0zA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CXV_A_0HKA501_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 3k0z PUTATIVE POLYKETIDE
CYCLASE
(Bacillus
cereus) 		5 / 12 ASP A 147
ALA A 102
ALA A 101
TYR A  63
CYH A 114
 None
None
NHE  A   1 (-3.4A)
None
None
 1.48A 5cxvA-3k0zA:
undetectable		 5cxvA-3k0zA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 3k0z PUTATIVE POLYKETIDE
CYCLASE
(Bacillus
cereus) 		3 / 3 ASP A  84
ARG A  91
ASP A 147
 None
NHE  A   1 (-3.9A)
None
 0.81A 5zvgA-3k0zA:
undetectable		 5zvgA-3k0zA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 3k0z PUTATIVE POLYKETIDE
CYCLASE
(Bacillus
cereus) 		3 / 3 ASP A  84
ARG A  91
ASP A 147
 None
NHE  A   1 (-3.9A)
None
 0.80A 5zvgB-3k0zA:
undetectable		 5zvgB-3k0zA:
20.00