SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3k10'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_A_FFOA1002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3k10 PROTEIN STN1
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 323
GLY A 325
LEU A 319
VAL A 377
SER A 332
 None
 0.98A 1dfoA-3k10A:
undetectable		 1dfoA-3k10A:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_B_FFOB2002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3k10 PROTEIN STN1
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 323
GLY A 325
LEU A 319
VAL A 377
SER A 332
 None
 0.98A 1dfoB-3k10A:
undetectable		 1dfoB-3k10A:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_C_FFOC3002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3k10 PROTEIN STN1
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 323
GLY A 325
LEU A 319
VAL A 377
SER A 332
 None
 0.98A 1dfoC-3k10A:
undetectable		 1dfoC-3k10A:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_D_FFOD4002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3k10 PROTEIN STN1
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 323
GLY A 325
LEU A 319
VAL A 377
SER A 332
 None
 0.99A 1dfoD-3k10A:
undetectable		 1dfoD-3k10A:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3k10 PROTEIN STN1
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 323
GLY A 325
LEU A 319
VAL A 377
SER A 332
 None
 0.95A 1eqbA-3k10A:
undetectable		 1eqbA-3k10A:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3k10 PROTEIN STN1
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 323
GLY A 325
LEU A 319
VAL A 377
SER A 332
 None
 0.95A 1eqbB-3k10A:
undetectable		 1eqbB-3k10A:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3k10 PROTEIN STN1
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 323
GLY A 325
LEU A 319
VAL A 377
SER A 332
 None
 0.96A 1eqbC-3k10A:
undetectable		 1eqbC-3k10A:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3k10 PROTEIN STN1
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 323
GLY A 325
LEU A 319
VAL A 377
SER A 332
 None
 0.96A 1eqbD-3k10A:
undetectable		 1eqbD-3k10A:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_1
(PROGESTERONE
RECEPTOR)		 3k10 PROTEIN STN1
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 336
LEU A 388
GLY A 387
PHE A 373
LEU A 376
 None
 1.33A 2w8yA-3k10A:
undetectable		 2w8yA-3k10A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV1_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 3k10 PROTEIN STN1
(Saccharomyces
cerevisiae) 		3 / 3 LYS A 457
LYS A 456
PRO A 460
 None
 0.94A 4dv1L-3k10A:
undetectable		 4dv1L-3k10A:
22.87