SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3k11'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_B_RBFB302_1
(PROTEIN (FLAVODOXIN))		 3k11 PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 8 THR A 117
GLY A 119
ASP A 120
TYR A 123
 None
 1.02A 1bu5B-3k11A:
undetectable		 1bu5B-3k11A:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3k11 PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A 228
ALA A 232
ALA A 230
GLN A 233
LEU A 164
 None
 0.97A 1fm6A-3k11A:
undetectable		 1fm6A-3k11A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HVY_B_D16B415_1
(THYMIDYLATE SYNTHASE)		 3k11 PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A 198
ASP A 223
LEU A 164
GLY A 227
ALA A 210
 None
 1.31A 1hvyB-3k11A:
undetectable		 1hvyB-3k11A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R9O_A_FLPA501_1
(CYTOCHROME P450 2C9)		 3k11 PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 VAL A 381
GLY A 427
ALA A 428
THR A 118
LEU A 111
 None
None
None
EDO  A   1 ( 4.5A)
None
 1.10A 1r9oA-3k11A:
undetectable		 1r9oA-3k11A:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_E_9CRE1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3k11 PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A 228
ALA A 232
ALA A 230
GLN A 233
LEU A 164
 None
 0.96A 1xdkE-3k11A:
undetectable		 1xdkE-3k11A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIU_B_9CRB202_1
(RXR-LIKE PROTEIN)		 3k11 PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A 228
ALA A 232
ALA A 230
GLN A 233
LEU A 164
 None
 0.94A 1xiuB-3k11A:
undetectable		 1xiuB-3k11A:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZEA_A_DHIA6_0
(MONOCLONAL
ANTI-CHOLERA TOXIN
IGG1 KAPPA ANTIBODY,
H CHAIN
MONOCLONAL
ANTI-CHOLERA TOXIN
IGG1 KAPPA ANTIBODY,
L CHAIN
SHORT SYNTHETIC
D-AMINO ACID PEPTIDE
D2)		 3k11 PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		3 / 3 TRP A 284
ARG A 410
PHE A 406
 None
 1.31A 1zeaH-3k11A:
undetectable
1zeaL-3k11A:
undetectable		 1zeaH-3k11A:
17.78
1zeaL-3k11A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_A_RBFA191_1
(LUMAZINE PROTEIN)		 3k11 PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 VAL A  59
ALA A 114
THR A 117
THR A 118
ILE A 431
 None
None
None
EDO  A   1 ( 4.5A)
EDO  A   1 (-4.1A)
 0.81A 3a35A-3k11A:
undetectable		 3a35A-3k11A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_B_RBFB191_1
(LUMAZINE PROTEIN)		 3k11 PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 VAL A  59
ALA A 114
THR A 117
THR A 118
ILE A 431
 None
None
None
EDO  A   1 ( 4.5A)
EDO  A   1 (-4.1A)
 0.84A 3a35B-3k11A:
undetectable		 3a35B-3k11A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3B_A_RBFA191_1
(LUMAZINE PROTEIN)		 3k11 PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 VAL A  59
ALA A 114
THR A 117
THR A 118
ILE A 431
 None
None
None
EDO  A   1 ( 4.5A)
EDO  A   1 (-4.1A)
 0.81A 3a3bA-3k11A:
undetectable		 3a3bA-3k11A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3k11 PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A 228
ALA A 232
GLN A 233
LEU A 298
LEU A 164
 None
 1.13A 3dzyA-3k11A:
undetectable		 3dzyA-3k11A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM3_B_478B200_1
(PROTEASE)		 3k11 PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 10 GLY A 383
ALA A 382
VAL A  52
GLY A 377
LEU A 376
 None
 0.85A 3em3A-3k11A:
undetectable		 3em3A-3k11A:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3k11 PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 9 GLY A 421
VAL A 106
ILE A  63
VAL A  59
VAL A 391
 None
 1.40A 3fhjD-3k11A:
undetectable		 3fhjD-3k11A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3k11 PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 9 GLY A 421
VAL A 106
ILE A  63
VAL A  59
VAL A 391
 None
 1.40A 3fhjF-3k11A:
undetectable		 3fhjF-3k11A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_B_CGEB501_1
(CYTOCHROME P450 2B4)		 3k11 PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 8 ILE A  56
THR A 107
VAL A 391
VAL A  59
 None
 0.91A 3me6B-3k11A:
undetectable		 3me6B-3k11A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_B_SAMB220_0
(16S RRNA METHYLASE)		 3k11 PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 GLY A 105
ALA A 113
ALA A 114
THR A 124
LEU A 111
 None
None
None
EDO  A  17 (-3.8A)
None
 1.04A 3mteB-3k11A:
undetectable		 3mteB-3k11A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_A_SAMA6735_0
(16S RRNA METHYLASE)		 3k11 PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 GLY A 105
ALA A 113
ALA A 114
THR A 124
LEU A 111
 None
None
None
EDO  A  17 (-3.8A)
None
 1.04A 3p2kA-3k11A:
undetectable		 3p2kA-3k11A:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3V_A_TOPA193_1
(DIHYDROFOLATE
REDUCTASE)		 3k11 PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 5 ASP A 300
ILE A 228
PRO A 229
PHE A 225
 None
 1.24A 3s3vA-3k11A:
undetectable		 3s3vA-3k11A:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP3_B_RBTB1129_1
(B-CELL LYMPHOMA 6
PROTEIN)		 3k11 PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 130
LEU A 134
GLY A 105
SER A 101
 None
 1.00A 4cp3A-3k11A:
undetectable
4cp3B-3k11A:
undetectable		 4cp3A-3k11A:
13.96
4cp3B-3k11A:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QRC_A_0LIA802_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 3k11 PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ALA A 382
VAL A 381
LEU A 293
ALA A 426
LEU A 356
 None
 1.18A 4qrcA-3k11A:
undetectable		 4qrcA-3k11A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE2_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3k11 PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 5 ALA A  61
TYR A  62
PRO A  68
PHE A  97
 None
 1.42A 4ze2A-3k11A:
undetectable		 4ze2A-3k11A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_1_BEZ1801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3k11 PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		3 / 3 LEU A 111
PHE A 131
ILE A 112
 None
 0.71A 5dzk1-3k11A:
undetectable
5dzkF-3k11A:
undetectable
5dzkM-3k11A:
undetectable		 5dzk1-3k11A:
12.50
5dzkF-3k11A:
20.18
5dzkM-3k11A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAN_A_9CRA503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3k11 PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A 228
ALA A 232
ALA A 230
GLN A 233
LEU A 164
 None
 0.92A 5uanA-3k11A:
undetectable		 5uanA-3k11A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_B_RBFB502_1
(RIBOFLAVIN LYASE)		 3k11 PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ALA A 357
GLY A 377
ALA A 114
VAL A  52
THR A 117
 None
 0.98A 5w4zB-3k11A:
undetectable		 5w4zB-3k11A:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_E_D16E402_1
(THYMIDYLATE SYNTHASE)		 3k11 PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 6 ILE A 198
ASP A 223
LEU A 164
GLY A 227
 None
 0.99A 5x5qE-3k11A:
undetectable		 5x5qE-3k11A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_C_MTXC402_1
(THYMIDYLATE SYNTHASE)		 3k11 PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 9 ILE A 198
ASP A 223
LEU A 164
GLY A 227
ALA A 210
 None
 1.38A 5x66C-3k11A:
undetectable		 5x66C-3k11A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_C_9CRC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3k11 PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A 228
ALA A 232
ALA A 230
GLN A 233
LEU A 164
 None
 1.04A 5z12C-3k11A:
undetectable		 5z12C-3k11A:
10.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3k11 PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A 228
ALA A 232
ALA A 230
GLN A 233
LEU A 164
 None
 0.94A 6a5yD-3k11A:
undetectable		 6a5yD-3k11A:
10.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Z_L_9CRL501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3k11 PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A 228
ALA A 232
ALA A 230
GLN A 233
LEU A 164
 None
 0.94A 6a5zL-3k11A:
undetectable		 6a5zL-3k11A:
10.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A60_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3k11 PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A 228
ALA A 232
ALA A 230
GLN A 233
LEU A 164
 None
 0.99A 6a60D-3k11A:
undetectable		 6a60D-3k11A:
10.78