SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3k12'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_A_STRA1001_2
(MINERALOCORTICOID
RECEPTOR)		 3k12 UNCHARACTERIZED
PROTEIN A6V7T0
(Pseudomonas
aeruginosa) 		4 / 4 LEU A  79
LEU A  99
SER A  98
LEU A  69
 None
 1.11A 1ya3A-3k12A:
undetectable		 1ya3A-3k12A:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6R_B_CRNB603_1
(CREATINE KINASE
B-TYPE)		 3k12 UNCHARACTERIZED
PROTEIN A6V7T0
(Pseudomonas
aeruginosa) 		4 / 6 THR A  23
VAL A  24
LEU A  64
SER A  58
 None
 1.26A 3b6rB-3k12A:
undetectable		 3b6rB-3k12A:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_C_QDNC602_1
(CYTOCHROME P450 2D6)		 3k12 UNCHARACTERIZED
PROTEIN A6V7T0
(Pseudomonas
aeruginosa) 		5 / 11 GLY A  28
GLU A  16
GLN A  29
ALA A  31
ASP A  32
 None
 1.38A 4wnuC-3k12A:
undetectable		 4wnuC-3k12A:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_2
(-)		 3k12 UNCHARACTERIZED
PROTEIN A6V7T0
(Pseudomonas
aeruginosa) 		4 / 8 VAL A 114
TYR A  25
ASN A  22
GLU A 118
 None
 1.29A 6gneB-3k12A:
undetectable		 6gneB-3k12A:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3k12 UNCHARACTERIZED
PROTEIN A6V7T0
(Pseudomonas
aeruginosa) 		4 / 6 ILE A  49
LEU A  53
ARG A  95
THR A  94
 None
 1.11A 6nmfN-3k12A:
undetectable
6nmfW-3k12A:
undetectable		 6nmfN-3k12A:
12.99
6nmfW-3k12A:
20.34