SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3k13'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q8J_A_C2FA801_0
(5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		7 / 12 ARG A 359
ASP A 431
ASN A 452
ASP A 519
GLY A 558
SER A 560
ARG A 573
 None
THH  A 642 (-3.3A)
THH  A 642 (-3.0A)
THH  A 642 (-3.4A)
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 (-3.1A)
 1.26A 1q8jA-3k13A:
12.3		 1q8jA-3k13A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q8J_A_C2FA801_0
(5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		9 / 12 GLU A 358
ASN A 361
ASP A 431
ASN A 452
ASP A 519
GLY A 558
SER A 560
ARG A 573
ILE A 593
 THH  A 642 ( 3.5A)
GOL  A 643 (-3.1A)
THH  A 642 (-3.3A)
THH  A 642 (-3.0A)
THH  A 642 (-3.4A)
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 (-3.1A)
THH  A 642 (-4.2A)
 0.47A 1q8jA-3k13A:
12.3		 1q8jA-3k13A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q8J_A_C2FA801_0
(5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		8 / 12 GLU A 358
ASN A 361
ASP A 431
GLY A 558
SER A 560
PHE A 564
ARG A 573
ILE A 593
 THH  A 642 ( 3.5A)
GOL  A 643 (-3.1A)
THH  A 642 (-3.3A)
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
None
THH  A 642 (-3.1A)
THH  A 642 (-4.2A)
 0.79A 1q8jA-3k13A:
12.3		 1q8jA-3k13A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q8J_B_C2FB802_0
(5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		9 / 12 GLU A 358
ASN A 361
ASP A 431
ASN A 452
GLY A 558
SER A 560
ASN A 561
ARG A 573
ILE A 593
 THH  A 642 ( 3.5A)
GOL  A 643 (-3.1A)
THH  A 642 (-3.3A)
THH  A 642 (-3.0A)
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 ( 3.3A)
THH  A 642 (-3.1A)
THH  A 642 (-4.2A)
 0.52A 1q8jB-3k13A:
12.3		 1q8jB-3k13A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.76A 1v54A-3k13A:
undetectable
1v54J-3k13A:
undetectable		 1v54A-3k13A:
20.20
1v54J-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.65A 1v54N-3k13A:
undetectable
1v54W-3k13A:
undetectable		 1v54N-3k13A:
20.20
1v54W-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.65A 1v55A-3k13A:
undetectable
1v55J-3k13A:
undetectable		 1v55A-3k13A:
20.20
1v55J-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 8 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.68A 1v55N-3k13A:
undetectable
1v55W-3k13A:
undetectable		 1v55N-3k13A:
20.20
1v55W-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.80A 2dyrA-3k13A:
undetectable
2dyrJ-3k13A:
undetectable		 2dyrA-3k13A:
20.20
2dyrJ-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.76A 2dyrN-3k13A:
undetectable
2dyrW-3k13A:
undetectable		 2dyrN-3k13A:
20.20
2dyrW-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_J_CHDJ101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.80A 2dysA-3k13A:
undetectable
2dysJ-3k13A:
undetectable		 2dysA-3k13A:
20.20
2dysJ-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_W_CHDW101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.68A 2dysN-3k13A:
undetectable
2dysW-3k13A:
undetectable		 2dysN-3k13A:
20.20
2dysW-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASP A 396
GLY A 558
SER A 560
ASN A 561
ARG A 573
 THH  A 642 ( 4.7A)
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 ( 3.3A)
THH  A 642 (-3.1A)
 0.91A 2e7fA-3k13A:
29.7		 2e7fA-3k13A:
26.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		8 / 12 GLU A 358
ASP A 431
ASN A 452
GLY A 558
SER A 560
ASN A 561
ARG A 573
ILE A 593
 THH  A 642 ( 3.5A)
THH  A 642 (-3.3A)
THH  A 642 (-3.0A)
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 ( 3.3A)
THH  A 642 (-3.1A)
THH  A 642 (-4.2A)
 0.28A 2e7fA-3k13A:
29.7		 2e7fA-3k13A:
26.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		7 / 12 GLU A 358
ASN A 452
GLY A 558
SER A 560
ASN A 561
ARG A 573
ILE A 593
 THH  A 642 ( 3.5A)
THH  A 642 (-3.0A)
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 ( 3.3A)
THH  A 642 (-3.1A)
THH  A 642 (-4.2A)
 0.26A 2e7fB-3k13A:
29.8		 2e7fB-3k13A:
26.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.75A 2eijA-3k13A:
undetectable
2eijJ-3k13A:
undetectable		 2eijA-3k13A:
20.20
2eijJ-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 8 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.68A 2eijN-3k13A:
undetectable
2eijW-3k13A:
undetectable		 2eijN-3k13A:
20.20
2eijW-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.72A 2eikA-3k13A:
undetectable
2eikJ-3k13A:
undetectable		 2eikA-3k13A:
20.20
2eikJ-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 8 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.65A 2eikN-3k13A:
0.4
2eikW-3k13A:
undetectable		 2eikN-3k13A:
20.20
2eikW-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.74A 2eilA-3k13A:
undetectable
2eilJ-3k13A:
undetectable		 2eilA-3k13A:
20.20
2eilJ-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 8 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.68A 2eilN-3k13A:
undetectable
2eilW-3k13A:
undetectable		 2eilN-3k13A:
20.20
2eilW-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 5 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.69A 2eimJ-3k13A:
undetectable		 2eimJ-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 5 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.67A 2eimW-3k13A:
undetectable		 2eimW-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 8 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.68A 2einA-3k13A:
undetectable
2einJ-3k13A:
undetectable		 2einA-3k13A:
20.20
2einJ-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.73A 2einN-3k13A:
undetectable
2einW-3k13A:
undetectable		 2einN-3k13A:
20.20
2einW-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_2
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ASN A 521
ILE A 540
MET A 589
 None
 0.68A 2h42C-3k13A:
undetectable		 2h42C-3k13A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		7 / 12 GLU A 358
ASP A 431
ASN A 452
GLY A 558
SER A 560
ARG A 573
ILE A 593
 THH  A 642 ( 3.5A)
THH  A 642 (-3.3A)
THH  A 642 (-3.0A)
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 (-3.1A)
THH  A 642 (-4.2A)
 0.29A 2ogyA-3k13A:
29.6		 2ogyA-3k13A:
25.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		7 / 12 GLU A 358
ASP A 431
ASN A 452
GLY A 558
SER A 560
ARG A 573
ILE A 593
 THH  A 642 ( 3.5A)
THH  A 642 (-3.3A)
THH  A 642 (-3.0A)
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 (-3.1A)
THH  A 642 (-4.2A)
 0.27A 2ogyB-3k13A:
29.8		 2ogyB-3k13A:
25.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_B_RIMB299_1
(MATRIX PROTEIN 2)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 6 LEU A 505
LEU A 504
ILE A 470
ARG A 468
 None
 0.97A 2rlfB-3k13A:
undetectable
2rlfC-3k13A:
undetectable		 2rlfB-3k13A:
10.43
2rlfC-3k13A:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YCJ_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASP A 396
ASP A 519
GLY A 558
SER A 560
ASN A 561
 THH  A 642 ( 4.7A)
THH  A 642 (-3.4A)
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 ( 3.3A)
 0.84A 2ycjA-3k13A:
29.6		 2ycjA-3k13A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YCJ_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		7 / 12 ASP A 431
ASN A 452
ASP A 519
GLY A 558
SER A 560
ASN A 561
ILE A 593
 THH  A 642 (-3.3A)
THH  A 642 (-3.0A)
THH  A 642 (-3.4A)
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 ( 3.3A)
THH  A 642 (-4.2A)
 0.28A 2ycjA-3k13A:
29.6		 2ycjA-3k13A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.87A 2zxwA-3k13A:
undetectable
2zxwJ-3k13A:
undetectable		 2zxwA-3k13A:
20.20
2zxwJ-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 8 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.66A 3abkA-3k13A:
undetectable
3abkJ-3k13A:
undetectable		 3abkA-3k13A:
20.20
3abkJ-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.86A 3ablA-3k13A:
undetectable
3ablJ-3k13A:
undetectable		 3ablA-3k13A:
20.20
3ablJ-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 8 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.78A 3ablN-3k13A:
undetectable
3ablW-3k13A:
undetectable		 3ablN-3k13A:
20.20
3ablW-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.86A 3abmA-3k13A:
undetectable
3abmJ-3k13A:
undetectable		 3abmA-3k13A:
20.20
3abmJ-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 8 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.71A 3abmN-3k13A:
undetectable
3abmW-3k13A:
undetectable		 3abmN-3k13A:
20.20
3abmW-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 5 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.91A 3ag1J-3k13A:
undetectable		 3ag1J-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.98A 3ag1N-3k13A:
undetectable
3ag1W-3k13A:
undetectable		 3ag1N-3k13A:
20.20
3ag1W-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 5 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.70A 3ag2J-3k13A:
undetectable		 3ag2J-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.76A 3ag3A-3k13A:
undetectable
3ag3J-3k13A:
undetectable		 3ag3A-3k13A:
20.20
3ag3J-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 8 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.83A 3ag3N-3k13A:
undetectable
3ag3W-3k13A:
undetectable		 3ag3N-3k13A:
20.20
3ag3W-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 5 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.87A 3ag4J-3k13A:
undetectable		 3ag4J-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.83A 3asnA-3k13A:
undetectable
3asnJ-3k13A:
undetectable		 3asnA-3k13A:
20.20
3asnJ-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 8 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.69A 3asnN-3k13A:
undetectable
3asnW-3k13A:
undetectable		 3asnN-3k13A:
20.20
3asnW-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.79A 3asoA-3k13A:
undetectable
3asoJ-3k13A:
undetectable		 3asoA-3k13A:
20.20
3asoJ-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 8 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.66A 3asoN-3k13A:
undetectable
3asoW-3k13A:
undetectable		 3asoN-3k13A:
20.20
3asoW-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 8 VAL A 594
VAL A 394
ILE A 585
GLY A 592
 None
 0.72A 3hjoA-3k13A:
undetectable		 3hjoA-3k13A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 8 VAL A 594
VAL A 394
ILE A 585
GLY A 592
 None
 0.71A 3hjoB-3k13A:
undetectable		 3hjoB-3k13A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A 546
GLY A 544
ALA A 584
PHE A 518
ALA A 491
 None
 0.99A 3jb2A-3k13A:
undetectable		 3jb2A-3k13A:
14.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K13_A_THHA642_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		7 / 12 ASN A 361
GLY A 364
ARG A 366
ASP A 396
VAL A 478
GLY A 558
ASN A 561
 GOL  A 643 (-3.1A)
THH  A 642 (-3.7A)
THH  A 642 (-3.2A)
THH  A 642 ( 4.7A)
None
THH  A 642 (-3.3A)
THH  A 642 ( 3.3A)
 1.30A 3k13A-3k13A:
51.9		 3k13A-3k13A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K13_A_THHA642_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASN A 361
GLY A 364
ARG A 366
ASP A 431
GLY A 357
 GOL  A 643 (-3.1A)
THH  A 642 (-3.7A)
THH  A 642 (-3.2A)
THH  A 642 (-3.3A)
None
 1.20A 3k13A-3k13A:
51.9		 3k13A-3k13A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K13_A_THHA642_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASN A 361
GLY A 364
ASP A 431
GLY A 357
ARG A 573
 GOL  A 643 (-3.1A)
THH  A 642 (-3.7A)
THH  A 642 (-3.3A)
None
THH  A 642 (-3.1A)
 1.26A 3k13A-3k13A:
51.9		 3k13A-3k13A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K13_A_THHA642_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		10 / 12 GLU A 358
ASN A 361
GLY A 364
ARG A 366
ASP A 431
VAL A 478
GLY A 558
SER A 560
ASN A 561
ILE A 593
 THH  A 642 ( 3.5A)
GOL  A 643 (-3.1A)
THH  A 642 (-3.7A)
THH  A 642 (-3.2A)
THH  A 642 (-3.3A)
None
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 ( 3.3A)
THH  A 642 (-4.2A)
 0.02A 3k13A-3k13A:
51.9		 3k13A-3k13A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K13_A_THHA642_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		9 / 12 GLU A 358
ASN A 361
GLY A 364
ASP A 431
VAL A 478
GLY A 558
SER A 560
ARG A 567
ILE A 593
 THH  A 642 ( 3.5A)
GOL  A 643 (-3.1A)
THH  A 642 (-3.7A)
THH  A 642 (-3.3A)
None
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 (-3.4A)
THH  A 642 (-4.2A)
 0.64A 3k13A-3k13A:
51.9		 3k13A-3k13A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K13_A_THHA642_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ASN A 452
ASP A 519
ARG A 573
 THH  A 642 (-3.0A)
THH  A 642 (-3.4A)
THH  A 642 (-3.1A)
 0.06A 3k13A-3k13A:
51.9		 3k13A-3k13A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K13_B_THHB643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		8 / 12 ASN A 361
GLY A 364
ARG A 366
ASP A 396
VAL A 478
GLY A 558
ASN A 561
ARG A 573
 GOL  A 643 (-3.1A)
THH  A 642 (-3.7A)
THH  A 642 (-3.2A)
THH  A 642 ( 4.7A)
None
THH  A 642 (-3.3A)
THH  A 642 ( 3.3A)
THH  A 642 (-3.1A)
 1.30A 3k13B-3k13A:
50.5		 3k13B-3k13A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K13_B_THHB643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		6 / 12 ASN A 361
GLY A 364
ARG A 366
ASP A 431
ASN A 452
GLY A 357
 GOL  A 643 (-3.1A)
THH  A 642 (-3.7A)
THH  A 642 (-3.2A)
THH  A 642 (-3.3A)
THH  A 642 (-3.0A)
None
 1.47A 3k13B-3k13A:
50.5		 3k13B-3k13A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K13_B_THHB643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASN A 361
GLY A 364
ASP A 431
ASN A 452
ARG A 567
 GOL  A 643 (-3.1A)
THH  A 642 (-3.7A)
THH  A 642 (-3.3A)
THH  A 642 (-3.0A)
THH  A 642 (-3.4A)
 1.19A 3k13B-3k13A:
50.5		 3k13B-3k13A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K13_B_THHB643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASP A 431
ASN A 452
VAL A 478
GLY A 557
ILE A 593
 THH  A 642 (-3.3A)
THH  A 642 (-3.0A)
None
None
THH  A 642 (-4.2A)
 1.11A 3k13B-3k13A:
50.5		 3k13B-3k13A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K13_B_THHB643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		12 / 12 GLU A 358
ASN A 361
GLY A 364
ARG A 366
ASP A 431
ASN A 452
VAL A 478
GLY A 558
SER A 560
ASN A 561
ARG A 573
ILE A 593
 THH  A 642 ( 3.5A)
GOL  A 643 (-3.1A)
THH  A 642 (-3.7A)
THH  A 642 (-3.2A)
THH  A 642 (-3.3A)
THH  A 642 (-3.0A)
None
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 ( 3.3A)
THH  A 642 (-3.1A)
THH  A 642 (-4.2A)
 0.12A 3k13B-3k13A:
50.5		 3k13B-3k13A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K13_C_THHC643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		9 / 12 ASN A 361
GLY A 364
ARG A 366
ASP A 396
VAL A 478
GLY A 558
ASN A 561
PHE A 564
ARG A 573
 GOL  A 643 (-3.1A)
THH  A 642 (-3.7A)
THH  A 642 (-3.2A)
THH  A 642 ( 4.7A)
None
THH  A 642 (-3.3A)
THH  A 642 ( 3.3A)
None
THH  A 642 (-3.1A)
 1.24A 3k13C-3k13A:
50.1		 3k13C-3k13A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K13_C_THHC643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASN A 361
GLY A 364
ARG A 366
ASP A 431
GLY A 357
 GOL  A 643 (-3.1A)
THH  A 642 (-3.7A)
THH  A 642 (-3.2A)
THH  A 642 (-3.3A)
None
 1.24A 3k13C-3k13A:
50.1		 3k13C-3k13A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K13_C_THHC643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASN A 398
VAL A 478
GLY A 558
PHE A 564
ILE A 593
 None
None
THH  A 642 (-3.3A)
None
THH  A 642 (-4.2A)
 1.19A 3k13C-3k13A:
50.1		 3k13C-3k13A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K13_C_THHC643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		12 / 12 GLU A 358
ASN A 361
GLY A 364
ARG A 366
ASP A 431
VAL A 478
GLY A 558
SER A 560
ASN A 561
PHE A 564
ARG A 573
ILE A 593
 THH  A 642 ( 3.5A)
GOL  A 643 (-3.1A)
THH  A 642 (-3.7A)
THH  A 642 (-3.2A)
THH  A 642 (-3.3A)
None
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 ( 3.3A)
None
THH  A 642 (-3.1A)
THH  A 642 (-4.2A)
 0.18A 3k13C-3k13A:
50.1		 3k13C-3k13A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K13_C_THHC643_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ASN A 452
ASP A 519
ARG A 567
 THH  A 642 (-3.0A)
THH  A 642 (-3.4A)
THH  A 642 (-3.4A)
 0.29A 3k13C-3k13A:
50.1		 3k13C-3k13A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_B_9PLB1_1
(CYTOCHROME P450 2A13)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 6 ASN A 561
PHE A 564
ALA A 524
THR A 527
 THH  A 642 ( 3.3A)
None
None
None
 1.00A 3t3sB-3k13A:
undetectable		 3t3sB-3k13A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_C_9PLC1_1
(CYTOCHROME P450 2A13)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ASN A 561
PHE A 564
ALA A 524
THR A 527
 THH  A 642 ( 3.3A)
None
None
None
 0.93A 3t3sC-3k13A:
undetectable		 3t3sC-3k13A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_D_9PLD1_1
(CYTOCHROME P450 2A13)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 8 ASN A 561
PHE A 564
ALA A 524
THR A 527
 THH  A 642 ( 3.3A)
None
None
None
 0.92A 3t3sD-3k13A:
undetectable		 3t3sD-3k13A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_E_9PLE1_1
(CYTOCHROME P450 2A13)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 8 ASN A 561
PHE A 564
ALA A 524
THR A 527
 THH  A 642 ( 3.3A)
None
None
None
 0.92A 3t3sE-3k13A:
undetectable		 3t3sE-3k13A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_F_9PLF1_1
(CYTOCHROME P450 2A13)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 8 ASN A 561
PHE A 564
ALA A 524
THR A 527
 THH  A 642 ( 3.3A)
None
None
None
 0.99A 3t3sF-3k13A:
undetectable		 3t3sF-3k13A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.59A 3wg7N-3k13A:
undetectable
3wg7W-3k13A:
undetectable		 3wg7N-3k13A:
20.20
3wg7W-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJE_A_C2FA300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASN A 361
ASP A 396
ASP A 519
GLY A 558
ARG A 573
 GOL  A 643 (-3.1A)
THH  A 642 ( 4.7A)
THH  A 642 (-3.4A)
THH  A 642 (-3.3A)
THH  A 642 (-3.1A)
 1.48A 4djeA-3k13A:
29.1		 4djeA-3k13A:
26.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJE_A_C2FA300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		8 / 12 GLU A 358
ASN A 361
ASP A 431
ASP A 519
GLY A 558
SER A 560
ARG A 573
ILE A 593
 THH  A 642 ( 3.5A)
GOL  A 643 (-3.1A)
THH  A 642 (-3.3A)
THH  A 642 (-3.4A)
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 (-3.1A)
THH  A 642 (-4.2A)
 0.66A 4djeA-3k13A:
29.1		 4djeA-3k13A:
26.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJE_B_C2FB302_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASP A 396
ASN A 452
ASP A 519
GLY A 558
ASN A 561
 THH  A 642 ( 4.7A)
THH  A 642 (-3.0A)
THH  A 642 (-3.4A)
THH  A 642 (-3.3A)
THH  A 642 ( 3.3A)
 1.29A 4djeB-3k13A:
28.8		 4djeB-3k13A:
26.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJE_B_C2FB302_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		9 / 12 GLU A 358
ASP A 396
ASP A 431
ASN A 452
ASP A 519
GLY A 558
SER A 560
ASN A 561
ARG A 573
 THH  A 642 ( 3.5A)
THH  A 642 ( 4.7A)
THH  A 642 (-3.3A)
THH  A 642 (-3.0A)
THH  A 642 (-3.4A)
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 ( 3.3A)
THH  A 642 (-3.1A)
 0.59A 4djeB-3k13A:
28.8		 4djeB-3k13A:
26.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_A_C2FA300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		8 / 12 GLU A 358
ASN A 361
ASP A 519
GLY A 558
SER A 560
ASN A 561
ARG A 573
ILE A 593
 THH  A 642 ( 3.5A)
GOL  A 643 (-3.1A)
THH  A 642 (-3.4A)
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 ( 3.3A)
THH  A 642 (-3.1A)
THH  A 642 (-4.2A)
 0.45A 4djfA-3k13A:
29.2		 4djfA-3k13A:
26.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_B_C2FB300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		7 / 12 GLU A 358
ASP A 396
ASP A 431
ASN A 452
GLY A 558
SER A 560
ARG A 573
 THH  A 642 ( 3.5A)
THH  A 642 ( 4.7A)
THH  A 642 (-3.3A)
THH  A 642 (-3.0A)
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 (-3.1A)
 0.53A 4djfB-3k13A:
29.1		 4djfB-3k13A:
26.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_A_NCTA501_1
(CYTOCHROME P450 2A13)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ASN A 561
PHE A 564
ALA A 524
THR A 527
 THH  A 642 ( 3.3A)
None
None
None
 0.91A 4ejgA-3k13A:
undetectable		 4ejgA-3k13A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_B_NCTB501_1
(CYTOCHROME P450 2A13)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 8 ASN A 561
PHE A 564
ALA A 524
THR A 527
 THH  A 642 ( 3.3A)
None
None
None
 0.86A 4ejgB-3k13A:
undetectable		 4ejgB-3k13A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 6 GLY A 557
GLY A 558
ASN A 561
ILE A 356
 None
THH  A 642 (-3.3A)
THH  A 642 ( 3.3A)
None
 0.95A 4fglD-3k13A:
undetectable		 4fglD-3k13A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_A_C2FA3000_0
(DIHYDROPTEROATE
SYNTHASE DHPS)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		6 / 12 GLU A 358
ASN A 361
ASP A 431
ASP A 519
GLY A 558
ILE A 593
 THH  A 642 ( 3.5A)
GOL  A 643 (-3.1A)
THH  A 642 (-3.3A)
THH  A 642 (-3.4A)
THH  A 642 (-3.3A)
THH  A 642 (-4.2A)
 0.59A 4o1eA-3k13A:
27.8		 4o1eA-3k13A:
29.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_B_C2FB4000_0
(DIHYDROPTEROATE
SYNTHASE DHPS)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 12 GLU A 358
ASN A 361
ASP A 431
GLY A 558
ILE A 593
 THH  A 642 ( 3.5A)
GOL  A 643 (-3.1A)
THH  A 642 (-3.3A)
THH  A 642 (-3.3A)
THH  A 642 (-4.2A)
 0.63A 4o1eB-3k13A:
27.5		 4o1eB-3k13A:
29.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UXQ_A_0LIA1752_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 7 VAL A 509
ILE A 516
ALA A 501
ILE A 517
 None
 0.74A 4uxqA-3k13A:
undetectable		 4uxqA-3k13A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.77A 5b1aA-3k13A:
undetectable
5b1aJ-3k13A:
undetectable		 5b1aA-3k13A:
20.20
5b1aJ-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.59A 5b1bA-3k13A:
undetectable
5b1bJ-3k13A:
undetectable		 5b1bA-3k13A:
20.20
5b1bJ-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.54A 5b1bN-3k13A:
undetectable
5b1bW-3k13A:
undetectable		 5b1bN-3k13A:
20.20
5b1bW-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.76A 5b3sA-3k13A:
undetectable
5b3sJ-3k13A:
undetectable		 5b3sA-3k13A:
20.20
5b3sJ-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.61A 5b3sN-3k13A:
undetectable
5b3sW-3k13A:
undetectable		 5b3sN-3k13A:
20.20
5b3sW-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.64A 5iy5A-3k13A:
undetectable
5iy5J-3k13A:
undetectable		 5iy5A-3k13A:
20.20
5iy5J-3k13A:
11.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.78A 5iy5N-3k13A:
undetectable
5iy5W-3k13A:
undetectable		 5iy5N-3k13A:
20.20
5iy5W-3k13A:
11.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_1
(PAVINE
N-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 5 PHE A 564
SER A 563
ASN A 361
ASP A 431
 None
None
GOL  A 643 (-3.1A)
THH  A 642 (-3.3A)
 1.33A 5kpcA-3k13A:
undetectable		 5kpcA-3k13A:
20.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOO_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		8 / 12 GLU A 358
GLY A 364
ASP A 396
VAL A 478
GLY A 558
SER A 560
ARG A 573
ILE A 593
 THH  A 642 ( 3.5A)
THH  A 642 (-3.7A)
THH  A 642 ( 4.7A)
None
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 (-3.1A)
THH  A 642 (-4.2A)
 0.39A 5vooA-3k13A:
39.0		 5vooA-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOO_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 5 ASN A 361
ASP A 431
ASN A 452
ASP A 519
ASN A 561
 GOL  A 643 (-3.1A)
THH  A 642 (-3.3A)
THH  A 642 (-3.0A)
THH  A 642 (-3.4A)
THH  A 642 ( 3.3A)
 0.28A 5vooA-3k13A:
39.0		 5vooA-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOO_B_C2FB702_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		8 / 12 GLU A 358
ASN A 361
GLY A 364
ASP A 396
VAL A 478
GLY A 558
SER A 560
ILE A 593
 THH  A 642 ( 3.5A)
GOL  A 643 (-3.1A)
THH  A 642 (-3.7A)
THH  A 642 ( 4.7A)
None
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 (-4.2A)
 0.37A 5vooB-3k13A:
38.9		 5vooB-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOO_B_C2FB702_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 5 ASP A 396
ASN A 452
ASP A 519
ASN A 561
ARG A 573
 THH  A 642 ( 4.7A)
THH  A 642 (-3.0A)
THH  A 642 (-3.4A)
THH  A 642 ( 3.3A)
THH  A 642 (-3.1A)
 1.31A 5vooB-3k13A:
38.9		 5vooB-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOO_B_C2FB702_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 5 ASP A 431
ASN A 452
ASP A 519
ASN A 561
ARG A 573
 THH  A 642 (-3.3A)
THH  A 642 (-3.0A)
THH  A 642 (-3.4A)
THH  A 642 ( 3.3A)
THH  A 642 (-3.1A)
 0.25A 5vooB-3k13A:
38.9		 5vooB-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOO_C_C2FC702_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		8 / 12 GLU A 358
GLY A 364
ASP A 396
VAL A 478
GLY A 558
SER A 560
ARG A 573
ILE A 593
 THH  A 642 ( 3.5A)
THH  A 642 (-3.7A)
THH  A 642 ( 4.7A)
None
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 (-3.1A)
THH  A 642 (-4.2A)
 0.37A 5vooC-3k13A:
38.9		 5vooC-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOO_C_C2FC702_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 5 ASN A 361
ASP A 431
ASN A 452
ASP A 519
ASN A 561
 GOL  A 643 (-3.1A)
THH  A 642 (-3.3A)
THH  A 642 (-3.0A)
THH  A 642 (-3.4A)
THH  A 642 ( 3.3A)
 0.26A 5vooC-3k13A:
38.9		 5vooC-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOO_D_C2FD3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		7 / 12 ASN A 361
MET A 429
VAL A 478
GLY A 558
SER A 560
PHE A 564
ILE A 593
 GOL  A 643 (-3.1A)
None
None
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
None
THH  A 642 (-4.2A)
 0.73A 5vooD-3k13A:
38.4		 5vooD-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOO_D_C2FD3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASN A 398
ASP A 396
MET A 429
GLY A 558
ILE A 593
 None
THH  A 642 ( 4.7A)
None
THH  A 642 (-3.3A)
THH  A 642 (-4.2A)
 0.97A 5vooD-3k13A:
38.4		 5vooD-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOO_D_C2FD3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASP A 396
MET A 429
VAL A 478
GLY A 592
ILE A 356
 THH  A 642 ( 4.7A)
None
None
None
None
 1.15A 5vooD-3k13A:
38.4		 5vooD-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOO_D_C2FD3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		9 / 12 GLU A 358
ASN A 361
GLY A 364
ASP A 396
MET A 429
VAL A 478
GLY A 558
SER A 560
ILE A 593
 THH  A 642 ( 3.5A)
GOL  A 643 (-3.1A)
THH  A 642 (-3.7A)
THH  A 642 ( 4.7A)
None
None
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 (-4.2A)
 0.35A 5vooD-3k13A:
38.4		 5vooD-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOO_D_C2FD3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 5 ASP A 396
ASN A 452
ASP A 519
ASN A 561
ARG A 573
 THH  A 642 ( 4.7A)
THH  A 642 (-3.0A)
THH  A 642 (-3.4A)
THH  A 642 ( 3.3A)
THH  A 642 (-3.1A)
 1.34A 5vooD-3k13A:
38.4		 5vooD-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOO_D_C2FD3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 5 ASP A 431
ASN A 452
ASP A 519
ASN A 561
ARG A 573
 THH  A 642 (-3.3A)
THH  A 642 (-3.0A)
THH  A 642 (-3.4A)
THH  A 642 ( 3.3A)
THH  A 642 (-3.1A)
 0.28A 5vooD-3k13A:
38.4		 5vooD-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOO_E_C2FE3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASP A 396
MET A 429
VAL A 478
GLY A 592
ILE A 356
 THH  A 642 ( 4.7A)
None
None
None
None
 1.10A 5vooE-3k13A:
38.5		 5vooE-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOO_E_C2FE3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		9 / 12 GLU A 358
GLY A 364
ASP A 396
MET A 429
VAL A 478
GLY A 558
SER A 560
ARG A 573
ILE A 593
 THH  A 642 ( 3.5A)
THH  A 642 (-3.7A)
THH  A 642 ( 4.7A)
None
None
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 (-3.1A)
THH  A 642 (-4.2A)
 0.39A 5vooE-3k13A:
38.5		 5vooE-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOO_E_C2FE3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 5 ASN A 361
ASP A 431
ASN A 452
ASP A 519
ASN A 561
 GOL  A 643 (-3.1A)
THH  A 642 (-3.3A)
THH  A 642 (-3.0A)
THH  A 642 (-3.4A)
THH  A 642 ( 3.3A)
 0.28A 5vooE-3k13A:
38.5		 5vooE-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOO_F_C2FF3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		9 / 12 GLU A 358
ASN A 361
GLY A 364
ASP A 396
VAL A 478
GLY A 558
SER A 560
ARG A 573
ILE A 593
 THH  A 642 ( 3.5A)
GOL  A 643 (-3.1A)
THH  A 642 (-3.7A)
THH  A 642 ( 4.7A)
None
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 (-3.1A)
THH  A 642 (-4.2A)
 0.35A 5vooF-3k13A:
38.2		 5vooF-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOO_F_C2FF3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 4 ASP A 396
ASN A 452
ASP A 519
ASN A 561
 THH  A 642 ( 4.7A)
THH  A 642 (-3.0A)
THH  A 642 (-3.4A)
THH  A 642 ( 3.3A)
 1.39A 5vooF-3k13A:
38.2		 5vooF-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOO_F_C2FF3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 4 ASP A 431
ASN A 452
ASP A 519
ASN A 561
 THH  A 642 (-3.3A)
THH  A 642 (-3.0A)
THH  A 642 (-3.4A)
THH  A 642 ( 3.3A)
 0.23A 5vooF-3k13A:
38.2		 5vooF-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOP_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		6 / 12 ASN A 361
GLY A 364
ASP A 431
VAL A 478
GLY A 558
ASN A 561
 GOL  A 643 (-3.1A)
THH  A 642 (-3.7A)
THH  A 642 (-3.3A)
None
THH  A 642 (-3.3A)
THH  A 642 ( 3.3A)
 1.43A 5vopA-3k13A:
39.5		 5vopA-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOP_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASN A 398
ASP A 396
GLY A 558
ASN A 561
ILE A 593
 None
THH  A 642 ( 4.7A)
THH  A 642 (-3.3A)
THH  A 642 ( 3.3A)
THH  A 642 (-4.2A)
 0.93A 5vopA-3k13A:
39.5		 5vopA-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOP_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		10 / 12 GLU A 358
ASN A 361
GLY A 364
ASP A 396
VAL A 478
GLY A 558
SER A 560
ASN A 561
ARG A 573
ILE A 593
 THH  A 642 ( 3.5A)
GOL  A 643 (-3.1A)
THH  A 642 (-3.7A)
THH  A 642 ( 4.7A)
None
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 ( 3.3A)
THH  A 642 (-3.1A)
THH  A 642 (-4.2A)
 0.35A 5vopA-3k13A:
39.5		 5vopA-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOP_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ASP A 431
ASN A 452
ASP A 519
 THH  A 642 (-3.3A)
THH  A 642 (-3.0A)
THH  A 642 (-3.4A)
 0.14A 5vopA-3k13A:
39.5		 5vopA-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOP_B_C2FB3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		6 / 12 ASN A 361
GLY A 364
ASP A 431
VAL A 478
GLY A 558
ASN A 561
 GOL  A 643 (-3.1A)
THH  A 642 (-3.7A)
THH  A 642 (-3.3A)
None
THH  A 642 (-3.3A)
THH  A 642 ( 3.3A)
 1.46A 5vopB-3k13A:
39.0		 5vopB-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOP_B_C2FB3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		6 / 12 ASN A 398
ASP A 396
VAL A 478
GLY A 558
ASN A 561
ILE A 593
 None
THH  A 642 ( 4.7A)
None
THH  A 642 (-3.3A)
THH  A 642 ( 3.3A)
THH  A 642 (-4.2A)
 1.09A 5vopB-3k13A:
39.0		 5vopB-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOP_B_C2FB3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		10 / 12 GLU A 358
ASN A 361
GLY A 364
ASP A 396
VAL A 478
GLY A 558
SER A 560
ASN A 561
ARG A 573
ILE A 593
 THH  A 642 ( 3.5A)
GOL  A 643 (-3.1A)
THH  A 642 (-3.7A)
THH  A 642 ( 4.7A)
None
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 ( 3.3A)
THH  A 642 (-3.1A)
THH  A 642 (-4.2A)
 0.31A 5vopB-3k13A:
39.0		 5vopB-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOP_B_C2FB3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ASP A 431
ASN A 452
ASP A 519
 THH  A 642 (-3.3A)
THH  A 642 (-3.0A)
THH  A 642 (-3.4A)
 0.10A 5vopB-3k13A:
39.0		 5vopB-3k13A:
34.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 5 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.72A 5w97J-3k13A:
undetectable		 5w97J-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 5 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.83A 5wauJ-3k13A:
undetectable		 5wauJ-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 5 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 1.23A 5x19J-3k13A:
undetectable		 5x19J-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 5 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 1.06A 5x1bW-3k13A:
undetectable		 5x1bW-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 1.01A 5x1fA-3k13A:
undetectable
5x1fJ-3k13A:
undetectable		 5x1fA-3k13A:
20.20
5x1fJ-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 5 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.86A 5x1fW-3k13A:
undetectable		 5x1fW-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.90A 5xdxA-3k13A:
undetectable
5xdxJ-3k13A:
undetectable		 5xdxA-3k13A:
20.20
5xdxJ-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 8 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.74A 5xdxN-3k13A:
undetectable
5xdxW-3k13A:
undetectable		 5xdxN-3k13A:
20.20
5xdxW-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 5 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.74A 5z86J-3k13A:
undetectable		 5z86J-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.69A 5z86N-3k13A:
undetectable
5z86W-3k13A:
undetectable		 5z86N-3k13A:
20.20
5z86W-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.69A 5zcoN-3k13A:
undetectable
5zcoW-3k13A:
undetectable		 5zcoN-3k13A:
20.20
5zcoW-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.72A 5zcpA-3k13A:
undetectable
5zcpJ-3k13A:
undetectable		 5zcpA-3k13A:
20.20
5zcpJ-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 8 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.72A 5zcpN-3k13A:
undetectable
5zcpW-3k13A:
undetectable		 5zcpN-3k13A:
20.20
5zcpW-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 8 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.58A 5zcqN-3k13A:
undetectable
5zcqW-3k13A:
undetectable		 5zcqN-3k13A:
20.20
5zcqW-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 5 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 1.06A 6nknJ-3k13A:
undetectable		 6nknJ-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NM4_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 9 ILE A 516
ALA A 553
GLY A 552
GLY A 544
CYH A 498
 None
 1.09A 6nm4B-3k13A:
undetectable		 6nm4B-3k13A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.91A 6nmfA-3k13A:
undetectable
6nmfJ-3k13A:
undetectable		 6nmfA-3k13A:
20.20
6nmfJ-3k13A:
11.46