SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3k17'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CET_A_CLQA1001_0
(PROTEIN (L-LACTATE
DEHYDROGENASE))		 3k17 LIN0012 PROTEIN
(Listeria
innocua) 		5 / 9 GLY A 291
ILE A 294
ALA A 290
PHE A 249
ILE A 235
 None
 1.01A 1cetA-3k17A:
undetectable		 1cetA-3k17A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZM_A_BZMA600_0
(ODORANT-BINDING
PROTEIN)		 3k17 LIN0012 PROTEIN
(Listeria
innocua) 		4 / 8 ILE A  55
MET A 103
ASN A  85
LEU A  43
 None
 0.85A 1dzmA-3k17A:
undetectable		 1dzmA-3k17A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_A_CCSA417_0
(ESTROGEN RECEPTOR)		 3k17 LIN0012 PROTEIN
(Listeria
innocua) 		3 / 3 GLU A 342
LYS A 336
VAL A 338
 None
 0.95A 1l2iA-3k17A:
undetectable		 1l2iA-3k17A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_J_BEZJ5041_0
(CES1 PROTEIN)		 3k17 LIN0012 PROTEIN
(Listeria
innocua) 		4 / 4 GLY A 120
SER A 122
ILE A 166
HIS A 154
 None
 1.14A 1yajJ-3k17A:
undetectable		 1yajJ-3k17A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 3k17 LIN0012 PROTEIN
(Listeria
innocua) 		5 / 11 PHE A 137
ILE A  66
GLY A  67
ILE A  84
LEU A 133
 None
 1.01A 1z11A-3k17A:
undetectable		 1z11A-3k17A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APX_A_Z80A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 3k17 LIN0012 PROTEIN
(Listeria
innocua) 		5 / 12 THR A 353
PHE A 217
PHE A 327
LEU A 272
ALA A  20
 None
 1.42A 3apxA-3k17A:
undetectable		 3apxA-3k17A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		 3k17 LIN0012 PROTEIN
(Listeria
innocua) 		5 / 12 GLY A 321
GLY A 220
ALA A 303
ALA A 306
ASP A 304
 None
 0.88A 3keeC-3k17A:
undetectable		 3keeC-3k17A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD201_1
(PROTEIN S100-A4)		 3k17 LIN0012 PROTEIN
(Listeria
innocua) 		4 / 8 GLY A 220
PHE A 264
PHE A 217
PHE A 327
 None
 1.05A 3ko0D-3k17A:
undetectable
3ko0E-3k17A:
undetectable		 3ko0D-3k17A:
14.88
3ko0E-3k17A:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ201_1
(PROTEIN S100-A4)		 3k17 LIN0012 PROTEIN
(Listeria
innocua) 		4 / 8 PHE A 217
PHE A 327
GLY A 220
PHE A 264
 None
 1.01A 3ko0B-3k17A:
undetectable
3ko0J-3k17A:
undetectable		 3ko0B-3k17A:
14.88
3ko0J-3k17A:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS201_1
(PROTEIN S100-A4)		 3k17 LIN0012 PROTEIN
(Listeria
innocua) 		4 / 7 PHE A 217
PHE A 327
GLY A 220
PHE A 264
 None
 1.01A 3ko0K-3k17A:
undetectable
3ko0S-3k17A:
undetectable		 3ko0K-3k17A:
14.88
3ko0S-3k17A:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1W_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3k17 LIN0012 PROTEIN
(Listeria
innocua) 		4 / 7 TYR A  18
VAL A 232
ILE A 235
LEU A 283
 None
 0.99A 4l1wA-3k17A:
undetectable		 4l1wA-3k17A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_B_29SB601_2
(ESTROGEN RECEPTOR)		 3k17 LIN0012 PROTEIN
(Listeria
innocua) 		4 / 5 LEU A  45
GLU A 360
MET A 134
LEU A  91
 None
 1.36A 4xi3B-3k17A:
undetectable		 4xi3B-3k17A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_A_ASDA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3k17 LIN0012 PROTEIN
(Listeria
innocua) 		4 / 7 TYR A  18
VAL A 232
ILE A 235
LEU A 283
 None
 0.93A 4xo7A-3k17A:
undetectable		 4xo7A-3k17A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_A_HFGA802_0
(PROLINE--TRNA LIGASE)		 3k17 LIN0012 PROTEIN
(Listeria
innocua) 		5 / 12 LEU A 272
PHE A 217
PRO A 213
SER A 168
GLY A 172
 None
 1.27A 4ydqA-3k17A:
undetectable		 4ydqA-3k17A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZN7_A_DESA601_1
(ESTROGEN RECEPTOR)		 3k17 LIN0012 PROTEIN
(Listeria
innocua) 		5 / 12 ALA A 306
GLU A 307
LEU A 302
ARG A 281
LEU A 337
 None
 1.21A 4zn7A-3k17A:
undetectable		 4zn7A-3k17A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3k17 LIN0012 PROTEIN
(Listeria
innocua) 		4 / 5 GLU A  46
THR A  44
THR A  80
HIS A  76
 None
 1.19A 5axaC-3k17A:
undetectable		 5axaC-3k17A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_O_EVPO2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3k17 LIN0012 PROTEIN
(Listeria
innocua) 		4 / 6 SER A 153
GLU A  82
GLY A  15
GLY A 120
 None
 0.92A 5cdnC-3k17A:
2.4
5cdnD-3k17A:
undetectable		 5cdnC-3k17A:
22.36
5cdnD-3k17A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_P_EVPP2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3k17 LIN0012 PROTEIN
(Listeria
innocua) 		4 / 6 SER A 153
GLU A  82
GLY A  15
GLY A 120
 None
 0.92A 5cdnT-3k17A:
2.0
5cdnU-3k17A:
undetectable		 5cdnT-3k17A:
22.36
5cdnU-3k17A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_A_ILEA601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3k17 LIN0012 PROTEIN
(Listeria
innocua) 		4 / 6 ALA A 125
THR A 126
VAL A 129
VAL A 157
 None
 1.00A 5eckA-3k17A:
undetectable		 5eckA-3k17A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_D_ILED601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3k17 LIN0012 PROTEIN
(Listeria
innocua) 		4 / 6 ALA A 125
THR A 126
VAL A 129
VAL A 157
 None
 1.01A 5eckD-3k17A:
undetectable		 5eckD-3k17A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_A_ILEA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3k17 LIN0012 PROTEIN
(Listeria
innocua) 		4 / 6 ALA A 125
THR A 126
VAL A 129
VAL A 157
 None
 0.91A 5eclA-3k17A:
undetectable		 5eclA-3k17A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3k17 LIN0012 PROTEIN
(Listeria
innocua) 		4 / 8 ALA A 125
THR A 126
VAL A 129
VAL A 157
 None
 0.72A 5ecnD-3k17A:
undetectable		 5ecnD-3k17A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_CE9A402_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 3k17 LIN0012 PROTEIN
(Listeria
innocua) 		5 / 12 ALA A 326
THR A  35
PHE A 351
THR A 216
PRO A 213
 None
 1.02A 5k9dA-3k17A:
undetectable		 5k9dA-3k17A:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_A_RBFA201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 3k17 LIN0012 PROTEIN
(Listeria
innocua) 		5 / 12 GLU A 295
LEU A 283
GLY A 324
ALA A  20
ASN A 279
 None
 1.43A 5kc4A-3k17A:
undetectable		 5kc4A-3k17A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7F_A_SAMA301_0
(PUTATIVE
O-METHYLTRANSFERASE
RV1220C)		 3k17 LIN0012 PROTEIN
(Listeria
innocua) 		5 / 12 GLY A 313
GLY A 311
GLN A 284
ALA A 303
ASP A 304
 None
 1.19A 5x7fA-3k17A:
undetectable		 5x7fA-3k17A:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_A_RFPA502_1
(RIFAMPIN
MONOOXYGENASE)		 3k17 LIN0012 PROTEIN
(Listeria
innocua) 		5 / 12 VAL A 127
VAL A  19
PHE A 217
THR A 353
GLY A 354
 None
 1.24A 6brdA-3k17A:
undetectable		 6brdA-3k17A:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_A_ACRA602_1
(-)		 3k17 LIN0012 PROTEIN
(Listeria
innocua) 		5 / 12 GLY A 173
GLY A 172
VAL A 356
VAL A 127
GLY A  15
 None
 1.03A 6gneA-3k17A:
undetectable		 6gneA-3k17A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_1
(-)		 3k17 LIN0012 PROTEIN
(Listeria
innocua) 		5 / 12 GLY A 173
GLY A 172
VAL A 356
VAL A 127
GLY A  15
 None
 1.03A 6gneB-3k17A:
undetectable		 6gneB-3k17A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MHT_D_SAMD328_0
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI)		 3k17 LIN0012 PROTEIN
(Listeria
innocua) 		5 / 12 GLY A 324
GLY A 313
TRP A 221
ASP A 322
ASP A 111
 None
 1.12A 6mhtA-3k17A:
undetectable		 6mhtA-3k17A:
22.14