SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3k1i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXH_B_PACB1001_0
(PENICILLIN ACYLASE)		 3k1i PUTATIVE
UNCHARACTERIZED
PROTEIN
(Helicobacter
pylori) 		4 / 7 SER C  43
SER C 108
ALA C 101
ILE C 106
 None
 0.99A 1fxhA-3k1iC:
undetectable
1fxhB-3k1iC:
undetectable		 1fxhA-3k1iC:
21.86
1fxhB-3k1iC:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_2
(MINERALOCORTICOID
RECEPTOR)		 3k1i PUTATIVE
UNCHARACTERIZED
PROTEIN
(Helicobacter
pylori) 		4 / 5 LEU C  47
LEU C  50
LEU C 128
MET C 109
 None
 1.13A 2oaxF-3k1iC:
undetectable		 2oaxF-3k1iC:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1498_1
(CYTOCHROME P450 3A4)		 3k1i FLAGELLAR PROTEIN
(Helicobacter
pylori) 		5 / 9 LEU A  91
ILE A  31
ALA A 110
GLY A  82
LEU A  83
 None
 1.30A 2v0mB-3k1iA:
undetectable		 2v0mB-3k1iA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ICX_E_SC2E1_1
(CETUXIMAB FAB LIGHT
CHAIN
MEDITOPE)		 3k1i PUTATIVE
UNCHARACTERIZED
PROTEIN
(Helicobacter
pylori) 		3 / 3 VAL C 111
GLN C  51
CYH C  54
 None
 0.83A 5icxA-3k1iC:
undetectable
5icxE-3k1iC:
undetectable		 5icxA-3k1iC:
21.92
5icxE-3k1iC:
4.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 3k1i FLAGELLAR PROTEIN
(Helicobacter
pylori) 		5 / 12 SER A  35
PHE A  61
ARG A 111
GLY A 112
LEU A 113
 None
 0.95A 5m54E-3k1iA:
2.8		 5m54E-3k1iA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 3k1i FLAGELLAR PROTEIN
(Helicobacter
pylori) 		4 / 8 VAL A  96
ASN A  95
ASN A  55
ILE A  51
 None
 1.08A 6hzpA-3k1iA:
4.4		 6hzpA-3k1iA:
15.57