SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3k1l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3k1l FANCL
(Drosophila
melanogaster) 		4 / 7 LYS B 233
LEU B 232
PHE B 285
LEU B 281
 None
 1.04A 2eimP-3k1lB:
undetectable
2eimW-3k1lB:
undetectable		 2eimP-3k1lB:
21.37
2eimW-3k1lB:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN3_A_ID8A1356_1
(THYROXINE-BINDING
GLOBULIN)		 3k1l FANCL
(Drosophila
melanogaster) 		4 / 8 LEU B  93
LEU B  45
LYS B  44
LEU B  34
 None
 1.15A 2xn3A-3k1lB:
undetectable
2xn3B-3k1lB:
undetectable		 2xn3A-3k1lB:
23.15
2xn3B-3k1lB:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3k1l FANCL
(Drosophila
melanogaster) 		4 / 6 VAL B 166
SER B 217
LEU B 234
ILE B 215
 AU  B 385 (-3.9A)
None
None
None
 0.91A 3kk6A-3k1lB:
undetectable		 3kk6A-3k1lB:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M7R_A_VDXA425_1
(VITAMIN D3 RECEPTOR)		 3k1l FANCL
(Drosophila
melanogaster) 		5 / 12 LEU B  43
LEU B  34
SER B  36
VAL B  60
GLN B  61
 None
 1.29A 3m7rA-3k1lB:
undetectable		 3m7rA-3k1lB:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_B_SAMB220_0
(16S RRNA METHYLASE)		 3k1l FANCL
(Drosophila
melanogaster) 		5 / 12 GLY B 362
PRO B 365
PHE B 356
THR B 349
LEU B 350
 None
None
None
AU  B 391 (-4.4A)
None
 1.04A 3mteB-3k1lB:
undetectable		 3mteB-3k1lB:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_A_SAMA6735_0
(16S RRNA METHYLASE)		 3k1l FANCL
(Drosophila
melanogaster) 		5 / 12 GLY B 362
PRO B 365
PHE B 356
THR B 349
LEU B 350
 None
None
None
AU  B 391 (-4.4A)
None
 1.00A 3p2kA-3k1lB:
undetectable		 3p2kA-3k1lB:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA601_0
(LACCASE-1)		 3k1l FANCL
(Drosophila
melanogaster) 		4 / 5 HIS B 278
CYH B 207
ILE B 203
LEU B 206
 None
 1.42A 3qpkA-3k1lB:
undetectable		 3qpkA-3k1lB:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3k1l FANCL
(Drosophila
melanogaster) 		4 / 8 VAL B 341
HIS B 339
ILE B 313
PHE B 366
 None
ZN  B 383 (-2.7A)
None
None
 0.96A 4fglD-3k1lB:
undetectable		 4fglD-3k1lB:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUB_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 3k1l FANCL
(Drosophila
melanogaster) 		3 / 3 TYR B 197
ARG B 222
HIS B 219
 None
 0.84A 4fubA-3k1lB:
undetectable		 4fubA-3k1lB:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3k1l FANCL
(Drosophila
melanogaster) 		5 / 12 GLN B 211
LEU B 378
LEU B 343
GLY B 252
LEU B 371
 None
 1.08A 5jw1B-3k1lB:
undetectable		 5jw1B-3k1lB:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TOA_B_ESTB601_1
(ESTROGEN RECEPTOR
BETA)		 3k1l FANCL
(Drosophila
melanogaster) 		5 / 12 LEU B  18
LEU B  45
ILE B  92
LEU B  93
HIS B  88
 None
 1.27A 5toaB-3k1lB:
undetectable		 5toaB-3k1lB:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 3k1l FANCL
(Drosophila
melanogaster) 		4 / 6 LYS B 233
LEU B 232
PHE B 285
LEU B 281
 None
 1.05A 5x19P-3k1lB:
undetectable		 5x19P-3k1lB:
21.37