SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3k1n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4002_1
(SERUM ALBUMIN)		 3k1n HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
sp.
ADP1) 		4 / 6 LEU A 255
VAL A 234
VAL A 227
GLN A 228
 None
 1.11A 1e7aB-3k1nA:
undetectable		 1e7aB-3k1nA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_A_CHDA1150_0
(ALCOHOL
DEHYDROGENASE)		 3k1n HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
sp.
ADP1) 		5 / 11 SER A 284
HIS A 116
LEU A 123
LEU A 119
ILE A 109
 None
 1.37A 1ee2A-3k1nA:
undetectable		 1ee2A-3k1nA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_1
(ALCOHOL
DEHYDROGENASE)		 3k1n HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
sp.
ADP1) 		5 / 11 SER A 284
HIS A 116
LEU A 123
LEU A 119
ILE A 109
 None
 1.40A 1ee2B-3k1nA:
undetectable		 1ee2B-3k1nA:
20.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F78_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3k1n HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
sp.
ADP1) 		9 / 9 LEU A 100
LEU A 104
LEU A 105
ILE A 108
PHE A 144
LEU A 159
ARG A 160
ILE A 269
TYR A 293
 IMD  A 313 ( 4.1A)
CL  A 314 ( 4.1A)
IMD  A 313 ( 4.0A)
None
IMD  A 313 ( 4.9A)
None
CL  A 314 (-3.4A)
IMD  A 313 ( 4.1A)
IMD  A 313 (-4.7A)
 0.53A 2f78A-3k1nA:
32.3		 2f78A-3k1nA:
74.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F78_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3k1n HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
sp.
ADP1) 		6 / 7 VAL A  97
SER A  99
ARG A 146
LEU A 147
HIS A 206
THR A 267
 None
 0.75A 2f78A-3k1nA:
32.3		 2f78A-3k1nA:
74.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F78_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3k1n HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
sp.
ADP1) 		6 / 7 VAL A  97
SER A  99
LEU A 147
PHE A 203
HIS A 206
THR A 267
 None
 0.72A 2f78A-3k1nA:
32.3		 2f78A-3k1nA:
74.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F78_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3k1n HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
sp.
ADP1) 		9 / 9 LEU A 100
LEU A 104
LEU A 105
ILE A 108
PHE A 144
LEU A 159
ARG A 160
ILE A 269
TYR A 293
 IMD  A 313 ( 4.1A)
CL  A 314 ( 4.1A)
IMD  A 313 ( 4.0A)
None
IMD  A 313 ( 4.9A)
None
CL  A 314 (-3.4A)
IMD  A 313 ( 4.1A)
IMD  A 313 (-4.7A)
 0.52A 2f78B-3k1nA:
32.8		 2f78B-3k1nA:
74.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F78_B_BEZB1004_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3k1n HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
sp.
ADP1) 		7 / 7 VAL A  97
SER A  99
ARG A 146
LEU A 147
PHE A 203
HIS A 206
THR A 267
 None
 0.75A 2f78B-3k1nA:
32.8		 2f78B-3k1nA:
74.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F7A_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3k1n HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
sp.
ADP1) 		9 / 9 LEU A 100
LEU A 104
LEU A 105
ILE A 108
PHE A 144
LEU A 159
ARG A 160
ILE A 269
TYR A 293
 IMD  A 313 ( 4.1A)
CL  A 314 ( 4.1A)
IMD  A 313 ( 4.0A)
None
IMD  A 313 ( 4.9A)
None
CL  A 314 (-3.4A)
IMD  A 313 ( 4.1A)
IMD  A 313 (-4.7A)
 0.41A 2f7aA-3k1nA:
31.5		 2f7aA-3k1nA:
74.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F7A_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3k1n HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
sp.
ADP1) 		8 / 9 LEU A 100
LEU A 104
ILE A 108
PHE A 144
LEU A 159
ARG A 160
ILE A 269
TYR A 293
 IMD  A 313 ( 4.1A)
CL  A 314 ( 4.1A)
None
IMD  A 313 ( 4.9A)
None
CL  A 314 (-3.4A)
IMD  A 313 ( 4.1A)
IMD  A 313 (-4.7A)
 0.72A 2f7aB-3k1nA:
32.4		 2f7aB-3k1nA:
74.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F7A_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3k1n HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
sp.
ADP1) 		8 / 9 LEU A 100
LEU A 104
LEU A 105
ILE A 108
PHE A 144
LEU A 159
ILE A 269
TYR A 293
 IMD  A 313 ( 4.1A)
CL  A 314 ( 4.1A)
IMD  A 313 ( 4.0A)
None
IMD  A 313 ( 4.9A)
None
IMD  A 313 ( 4.1A)
IMD  A 313 (-4.7A)
 0.69A 2f7aB-3k1nA:
32.4		 2f7aB-3k1nA:
74.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F8D_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3k1n HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
sp.
ADP1) 		6 / 6 VAL A  97
SER A  99
ARG A 146
LEU A 147
PHE A 203
HIS A 206
 None
 0.64A 2f8dA-3k1nA:
22.3		 2f8dA-3k1nA:
74.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F8D_A_BEZA1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3k1n HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
sp.
ADP1) 		10 / 10 LEU A 100
GLY A 103
LEU A 104
LEU A 105
ILE A 108
PHE A 144
LEU A 159
ARG A 160
ILE A 269
TYR A 293
 IMD  A 313 ( 4.1A)
CL  A 314 ( 4.1A)
CL  A 314 ( 4.1A)
IMD  A 313 ( 4.0A)
None
IMD  A 313 ( 4.9A)
None
CL  A 314 (-3.4A)
IMD  A 313 ( 4.1A)
IMD  A 313 (-4.7A)
 0.51A 2f8dA-3k1nA:
34.1		 2f8dA-3k1nA:
74.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F8D_B_BEZB1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3k1n HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
sp.
ADP1) 		10 / 10 LEU A 100
GLY A 103
LEU A 104
LEU A 105
ILE A 108
PHE A 144
LEU A 159
ARG A 160
ILE A 269
TYR A 293
 IMD  A 313 ( 4.1A)
CL  A 314 ( 4.1A)
CL  A 314 ( 4.1A)
IMD  A 313 ( 4.0A)
None
IMD  A 313 ( 4.9A)
None
CL  A 314 (-3.4A)
IMD  A 313 ( 4.1A)
IMD  A 313 (-4.7A)
 0.54A 2f8dB-3k1nA:
35.0		 2f8dB-3k1nA:
74.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA608_1
(CHITINASE A)		 3k1n HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
sp.
ADP1) 		4 / 6 ASN A 175
SER A 171
ALA A 170
HIS A 169
 None
 1.17A 3aruA-3k1nA:
undetectable		 3aruA-3k1nA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3k1n HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
sp.
ADP1) 		4 / 8 LEU A 193
SER A 241
ALA A 236
ALA A 235
 None
 1.03A 3ax9B-3k1nA:
undetectable		 3ax9B-3k1nA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_C_URFC400_1
(URIDINE
PHOSPHORYLASE 1)		 3k1n HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
sp.
ADP1) 		4 / 8 GLY A 232
LEU A 231
LEU A 252
ILE A 250
 None
 0.84A 3nbqC-3k1nA:
undetectable		 3nbqC-3k1nA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PP1_A_ACTA590_0
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 3k1n HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
sp.
ADP1) 		4 / 5 GLU A 125
LEU A 100
GLN A 131
GLY A 145
 None
IMD  A 313 ( 4.1A)
None
None
 1.27A 3pp1A-3k1nA:
undetectable		 3pp1A-3k1nA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q1E_C_T44C128_1
(5-HYDROXYISOURATE
HYDROLASE)		 3k1n HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
sp.
ADP1) 		4 / 6 LEU A 184
PRO A 218
LEU A 187
LEU A 194
 None
 0.64A 3q1eA-3k1nA:
undetectable
3q1eC-3k1nA:
undetectable		 3q1eA-3k1nA:
16.11
3q1eC-3k1nA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q1E_C_T44C128_1
(5-HYDROXYISOURATE
HYDROLASE)		 3k1n HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
sp.
ADP1) 		4 / 6 LEU A 194
LEU A 184
PRO A 218
LEU A 187
 None
 0.74A 3q1eA-3k1nA:
undetectable
3q1eC-3k1nA:
undetectable		 3q1eA-3k1nA:
16.11
3q1eC-3k1nA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_2
(PROTEASE)		 3k1n HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
sp.
ADP1) 		5 / 11 ALA A 142
GLY A 145
ILE A 269
ILE A 109
ILE A  94
 None
None
IMD  A 313 ( 4.1A)
None
None
 1.01A 3s53B-3k1nA:
undetectable		 3s53B-3k1nA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ6_A_SAMA300_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3k1n HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
sp.
ADP1) 		5 / 12 TYR A 112
ILE A 121
ILE A 289
ILE A 109
ASP A 141
 None
 0.98A 3uj6A-3k1nA:
undetectable		 3uj6A-3k1nA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_A_ECLA1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 3k1n HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
sp.
ADP1) 		4 / 7 PHE A 211
ILE A 210
ILE A 240
ALA A 245
 None
 0.86A 6b5vA-3k1nA:
undetectable
6b5vC-3k1nA:
undetectable		 6b5vA-3k1nA:
19.75
6b5vC-3k1nA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_C_ECLC1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 3k1n HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
sp.
ADP1) 		4 / 7 PHE A 211
ILE A 210
ILE A 240
ALA A 245
 None
 0.85A 6b5vC-3k1nA:
undetectable
6b5vD-3k1nA:
undetectable		 6b5vC-3k1nA:
19.75
6b5vD-3k1nA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_D_ECLD1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 3k1n HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
sp.
ADP1) 		4 / 7 ALA A 245
PHE A 211
ILE A 210
ILE A 240
 None
 0.85A 6b5vB-3k1nA:
undetectable
6b5vD-3k1nA:
undetectable		 6b5vB-3k1nA:
19.75
6b5vD-3k1nA:
19.75