SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3k1r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3k1r HARMONIN
(Homo
sapiens) 		4 / 7 ILE A  50
LEU A  58
TYR A  74
LEU A  30
 None
 0.84A 1v55A-3k1rA:
undetectable
1v55J-3k1rA:
undetectable		 1v55A-3k1rA:
14.45
1v55J-3k1rA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3k1r HARMONIN
(Homo
sapiens) 		4 / 8 ILE A  50
LEU A  58
TYR A  74
LEU A  30
 None
 0.85A 1v55N-3k1rA:
undetectable
1v55W-3k1rA:
undetectable		 1v55N-3k1rA:
14.45
1v55W-3k1rA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3k1r HARMONIN
(Homo
sapiens) 		4 / 8 ILE A  50
LEU A  58
TYR A  74
LEU A  30
 None
 0.85A 2einA-3k1rA:
undetectable
2einJ-3k1rA:
undetectable		 2einA-3k1rA:
14.45
2einJ-3k1rA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_C_SNLC3001_1
(MINERALOCORTICOID
RECEPTOR)		 3k1r HARMONIN
USHER SYNDROME
TYPE-1G PROTEIN
(Homo
sapiens) 		5 / 12 LEU A 153
ALA B 442
LEU B 415
LEU B 396
THR A 156
 None
 1.48A 2oaxC-3k1rA:
undetectable		 2oaxC-3k1rA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3k1r HARMONIN
(Homo
sapiens) 		4 / 8 ILE A  50
LEU A  58
TYR A  74
LEU A  30
 None
 0.87A 3abkA-3k1rA:
undetectable
3abkJ-3k1rA:
undetectable		 3abkA-3k1rA:
14.45
3abkJ-3k1rA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3k1r HARMONIN
(Homo
sapiens) 		4 / 8 ILE A  50
LEU A  58
TYR A  74
LEU A  30
 None
 0.87A 3abmN-3k1rA:
undetectable
3abmW-3k1rA:
undetectable		 3abmN-3k1rA:
14.45
3abmW-3k1rA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3k1r HARMONIN
(Homo
sapiens) 		4 / 7 ILE A  50
LEU A  58
TYR A  74
LEU A  30
 None
 0.86A 3ag3A-3k1rA:
undetectable
3ag3J-3k1rA:
undetectable		 3ag3A-3k1rA:
14.45
3ag3J-3k1rA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3k1r HARMONIN
(Homo
sapiens) 		4 / 8 ILE A  50
LEU A  58
TYR A  74
LEU A  30
 None
 0.85A 3ag3N-3k1rA:
undetectable
3ag3W-3k1rA:
undetectable		 3ag3N-3k1rA:
14.45
3ag3W-3k1rA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 3k1r HARMONIN
(Homo
sapiens) 		4 / 8 ILE A  50
LEU A  58
TYR A  74
LEU A  30
 None
 0.84A 3asoN-3k1rA:
undetectable
3asoW-3k1rA:
undetectable		 3asoN-3k1rA:
14.45
3asoW-3k1rA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWW_A_ROCA1001_1
(ENDOTHIAPEPSIN)		 3k1r HARMONIN
USHER SYNDROME
TYPE-1G PROTEIN
(Homo
sapiens) 		5 / 12 GLY A 104
PHE A 188
ILE A 154
THR B 459
ILE A 151
 None
 1.09A 3pwwA-3k1rA:
undetectable		 3pwwA-3k1rA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_A_08JA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 3k1r HARMONIN
USHER SYNDROME
TYPE-1G PROTEIN
(Homo
sapiens) 		4 / 8 VAL A 102
LEU B 461
LEU A 100
ILE A 137
 None
 0.86A 3u5kA-3k1rA:
undetectable		 3u5kA-3k1rA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VHU_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 3k1r HARMONIN
USHER SYNDROME
TYPE-1G PROTEIN
(Homo
sapiens) 		5 / 12 LEU A 153
ALA B 442
LEU B 415
LEU B 396
THR A 156
 None
 1.46A 3vhuA-3k1rA:
undetectable		 3vhuA-3k1rA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_C_TYLC1184_1
(BROMODOMAIN
CONTAINING 2)		 3k1r HARMONIN
USHER SYNDROME
TYPE-1G PROTEIN
(Homo
sapiens) 		4 / 5 VAL A 102
LEU B 461
LEU A 100
ILE A 137
 None
 0.88A 4a9jC-3k1rA:
undetectable		 4a9jC-3k1rA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_F_ASWF101_1
(DNA TOPOISOMERASE
2-BETA)		 3k1r HARMONIN
USHER SYNDROME
TYPE-1G PROTEIN
(Homo
sapiens) 		4 / 6 PRO B 454
GLY A 104
ALA B 449
GLU A 107
 None
 1.10A 4g0uA-3k1rB:
undetectable		 4g0uA-3k1rB:
8.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZN7_B_DESB600_1
(ESTROGEN RECEPTOR)		 3k1r USHER SYNDROME
TYPE-1G PROTEIN
(Homo
sapiens) 		5 / 11 LEU B 440
ALA B 442
LEU B 396
LEU B 399
LEU B 418
 None
 1.34A 4zn7B-3k1rB:
undetectable		 4zn7B-3k1rB:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3k1r HARMONIN
(Homo
sapiens) 		4 / 7 ILE A  50
LEU A  58
TYR A  74
LEU A  30
 None
 0.86A 5b1aA-3k1rA:
undetectable
5b1aJ-3k1rA:
undetectable		 5b1aA-3k1rA:
14.45
5b1aJ-3k1rA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3k1r HARMONIN
(Homo
sapiens) 		4 / 7 ILE A  50
LEU A  58
TYR A  74
LEU A  30
 None
 0.88A 5b3sA-3k1rA:
undetectable
5b3sJ-3k1rA:
undetectable		 5b3sA-3k1rA:
14.45
5b3sJ-3k1rA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_I_IPHI101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 3k1r HARMONIN
USHER SYNDROME
TYPE-1G PROTEIN
(Homo
sapiens;
Homo
sapiens) 		4 / 6 VAL A 150
HIS A 147
LEU A 112
LEU B 461
 None
 1.24A 5hrqB-3k1rA:
undetectable
5hrqI-3k1rA:
undetectable
5hrqJ-3k1rA:
undetectable		 5hrqB-3k1rA:
12.58
5hrqI-3k1rA:
10.84
5hrqJ-3k1rA:
12.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3k1r HARMONIN
(Homo
sapiens) 		4 / 7 ILE A  50
LEU A  58
TYR A  74
LEU A  30
 None
 0.85A 5iy5A-3k1rA:
undetectable
5iy5J-3k1rA:
undetectable		 5iy5A-3k1rA:
14.45
5iy5J-3k1rA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3k1r HARMONIN
(Homo
sapiens) 		4 / 7 ILE A  50
LEU A  58
TYR A  74
LEU A  30
 None
 0.91A 5xdqN-3k1rA:
undetectable
5xdqW-3k1rA:
undetectable		 5xdqN-3k1rA:
14.45
5xdqW-3k1rA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 3k1r HARMONIN
(Homo
sapiens) 		4 / 7 ILE A  50
LEU A  58
TYR A  74
LEU A  30
 None
 0.90A 5xdxA-3k1rA:
undetectable
5xdxJ-3k1rA:
undetectable		 5xdxA-3k1rA:
14.45
5xdxJ-3k1rA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3k1r HARMONIN
(Homo
sapiens) 		4 / 7 ILE A  50
LEU A  58
TYR A  74
LEU A  30
 None
 0.88A 5zcpA-3k1rA:
undetectable
5zcpJ-3k1rA:
undetectable		 5zcpA-3k1rA:
14.45
5zcpJ-3k1rA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3k1r HARMONIN
(Homo
sapiens) 		4 / 8 ILE A  50
LEU A  58
TYR A  74
LEU A  30
 None
 0.87A 5zcpN-3k1rA:
undetectable
5zcpW-3k1rA:
undetectable		 5zcpN-3k1rA:
14.45
5zcpW-3k1rA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3k1r HARMONIN
(Homo
sapiens) 		4 / 7 ILE A  50
LEU A  58
TYR A  74
LEU A  30
 None
 0.86A 5zcqA-3k1rA:
undetectable
5zcqJ-3k1rA:
undetectable		 5zcqA-3k1rA:
14.45
5zcqJ-3k1rA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3k1r HARMONIN
(Homo
sapiens) 		4 / 7 ILE A  50
LEU A  58
TYR A  74
LEU A  30
 None
 0.94A 6nmfA-3k1rA:
undetectable
6nmfJ-3k1rA:
undetectable		 6nmfA-3k1rA:
14.45
6nmfJ-3k1rA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3k1r HARMONIN
(Homo
sapiens) 		4 / 7 ILE A  50
LEU A  58
TYR A  74
LEU A  30
 None
 0.95A 6nmpA-3k1rA:
1.7
6nmpJ-3k1rA:
undetectable		 6nmpA-3k1rA:
14.45
6nmpJ-3k1rA:
16.15