SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3k20'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_IMNA2001_1
(SERUM ALBUMIN)		 3k20 OXIDOREDUCTASE
(Corynebacterium
diphtheriae) 		5 / 10 SER A  89
ALA A 115
ALA A   9
LEU A  11
LEU A 130
 None
 1.09A 2bxqA-3k20A:
undetectable		 2bxqA-3k20A:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_A_J01A1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 3k20 OXIDOREDUCTASE
(Corynebacterium
diphtheriae) 		5 / 12 MET A 137
LEU A 106
ILE A 100
ALA A 105
LEU A 133
 None
 1.15A 2japA-3k20A:
5.0		 2japA-3k20A:
25.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_B_J01B1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 3k20 OXIDOREDUCTASE
(Corynebacterium
diphtheriae) 		5 / 12 MET A 137
LEU A 106
ILE A 100
ALA A 105
LEU A 133
 None
 1.12A 2japB-3k20A:
5.0		 2japB-3k20A:
25.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_C_J01C1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 3k20 OXIDOREDUCTASE
(Corynebacterium
diphtheriae) 		5 / 12 MET A 137
LEU A 106
ILE A 100
ALA A 105
LEU A 133
 None
 1.17A 2japC-3k20A:
5.0		 2japC-3k20A:
25.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_D_J01D1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 3k20 OXIDOREDUCTASE
(Corynebacterium
diphtheriae) 		5 / 12 MET A 137
LEU A 106
ILE A 100
ALA A 105
LEU A 133
 None
 1.15A 2japD-3k20A:
4.9		 2japD-3k20A:
25.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_B_017B200_2
(PROTEASE)		 3k20 OXIDOREDUCTASE
(Corynebacterium
diphtheriae) 		5 / 9 ALA A 148
GLY A 145
ILE A 113
ALA A  21
ILE A  20
 None
 0.92A 3ektB-3k20A:
undetectable		 3ektB-3k20A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKW_B_DR7B100_1
(PROTEASE)		 3k20 OXIDOREDUCTASE
(Corynebacterium
diphtheriae) 		5 / 10 ALA A 148
GLY A 145
ILE A 113
ALA A  21
ILE A  20
 None
 0.91A 3ekwA-3k20A:
undetectable		 3ekwA-3k20A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_1
(ADENOSYLHOMOCYSTEINA
SE)		 3k20 OXIDOREDUCTASE
(Corynebacterium
diphtheriae) 		5 / 12 THR A  17
LEU A 130
LEU A 126
GLY A 145
PHE A 161
 SO4  A 182 (-3.7A)
None
None
None
None
 1.24A 3g1uB-3k20A:
4.4		 3g1uB-3k20A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_D_ADND438_1
(ADENOSYLHOMOCYSTEINA
SE)		 3k20 OXIDOREDUCTASE
(Corynebacterium
diphtheriae) 		5 / 12 THR A  17
LEU A 130
LEU A 126
GLY A 145
PHE A 161
 SO4  A 182 (-3.7A)
None
None
None
None
 1.22A 3g1uD-3k20A:
3.1		 3g1uD-3k20A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_C_ADNC500_1
(ADENOSYLHOMOCYSTEINA
SE)		 3k20 OXIDOREDUCTASE
(Corynebacterium
diphtheriae) 		5 / 12 THR A  17
LEU A 130
LEU A 126
GLY A 145
PHE A 161
 SO4  A 182 (-3.7A)
None
None
None
None
 1.20A 3n58C-3k20A:
3.8		 3n58C-3k20A:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3k20 OXIDOREDUCTASE
(Corynebacterium
diphtheriae) 		5 / 12 GLU A  37
GLY A 170
ALA A 168
LEU A   4
ILE A  24
 None
 1.19A 4hytA-3k20A:
2.5		 4hytA-3k20A:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_C_OBNC2004_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3k20 OXIDOREDUCTASE
(Corynebacterium
diphtheriae) 		5 / 12 GLU A  37
GLY A 170
ALA A 168
LEU A   4
ILE A  24
 None
 1.18A 4hytC-3k20A:
undetectable		 4hytC-3k20A:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_A_IMNA201_1
(TRANSTHYRETIN)		 3k20 OXIDOREDUCTASE
(Corynebacterium
diphtheriae) 		4 / 7 LEU A  93
ALA A   9
THR A  83
VAL A  81
 None
 1.01A 4ik7A-3k20A:
undetectable		 4ik7A-3k20A:
23.94