SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3k2c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JGS_A_SALA256_1
(MULTIPLE ANTIBIOTIC
RESISTANCE PROTEIN
MARR)		 3k2c PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Encephalitozoon
cuniculi) 		4 / 7 VAL A  24
LEU A  27
ARG A  40
VAL A 168
 None
 0.62A 1jgsA-3k2cA:
undetectable		 1jgsA-3k2cA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		 3k2c PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Encephalitozoon
cuniculi) 		4 / 7 GLY A  83
TYR A  70
GLY A  77
THR A  76
 None
 0.78A 3tajA-3k2cA:
undetectable		 3tajA-3k2cA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVD_A_SAMA502_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 3k2c PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Encephalitozoon
cuniculi) 		5 / 12 TYR A 148
ILE A 163
ARG A 164
VAL A  13
ILE A  23
 None
 1.05A 4rvdA-3k2cA:
undetectable		 4rvdA-3k2cA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_S_PCFS603_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)		 3k2c PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Encephalitozoon
cuniculi) 		4 / 7 GLN A 114
PHE A  56
VAL A 155
SER A  54
 None
 0.87A 6hu9S-3k2cA:
undetectable
6hu9q-3k2cA:
undetectable		 6hu9S-3k2cA:
20.11
6hu9q-3k2cA:
22.83