SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3k2d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DIT_P_2PPP1_1
(ALPHA-THROMBIN
PEPTIDE INHIBITOR
CVS995)		 3k2d ABC-TYPE METAL ION
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Vibrio
vulnificus) 		4 / 6 LEU A 163
GLU A  97
ASP A  93
PRO A  90
 None
 1.23A 1ditH-3k2dA:
undetectable
1ditP-3k2dA:
undetectable		 1ditH-3k2dA:
22.96
1ditP-3k2dA:
5.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JLB_A_NVPA999_1
(HIV-1 RT A-CHAIN)		 3k2d ABC-TYPE METAL ION
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Vibrio
vulnificus) 		4 / 8 LEU A 154
VAL A 131
GLY A 130
LEU A 196
 None
 0.94A 1jlbA-3k2dA:
undetectable		 1jlbA-3k2dA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S1X_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)		 3k2d ABC-TYPE METAL ION
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Vibrio
vulnificus) 		4 / 8 LEU A 154
VAL A 131
GLY A 130
LEU A 196
 None
 0.95A 1s1xA-3k2dA:
undetectable		 1s1xA-3k2dA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O14_A_NIOA300_1
(ANTI-ECFSIGMA
FACTOR, CHRR)		 3k2d ABC-TYPE METAL ION
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Vibrio
vulnificus) 		5 / 7 ALA A 126
SER A 123
VAL A 216
VAL A 121
LEU A 127
 None
 1.32A 3o14A-3k2dA:
undetectable		 3o14A-3k2dA:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_A_URFA302_1
(URIDINE
PHOSPHORYLASE)		 3k2d ABC-TYPE METAL ION
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Vibrio
vulnificus) 		4 / 7 THR A  71
GLN A  87
ALA A  75
ILE A  81
 None
 0.89A 4txnA-3k2dA:
undetectable		 4txnA-3k2dA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_B_URFB302_1
(URIDINE
PHOSPHORYLASE)		 3k2d ABC-TYPE METAL ION
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Vibrio
vulnificus) 		4 / 7 THR A  71
GLN A  87
ALA A  75
ILE A  81
 None
 0.88A 4txnB-3k2dA:
undetectable		 4txnB-3k2dA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_C_URFC302_1
(URIDINE
PHOSPHORYLASE)		 3k2d ABC-TYPE METAL ION
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Vibrio
vulnificus) 		4 / 7 THR A  71
GLN A  87
ALA A  75
ILE A  81
 None
 0.91A 4txnC-3k2dA:
undetectable		 4txnC-3k2dA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_D_URFD302_1
(URIDINE
PHOSPHORYLASE)		 3k2d ABC-TYPE METAL ION
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Vibrio
vulnificus) 		4 / 7 THR A  71
GLN A  87
ALA A  75
ILE A  81
 None
 0.87A 4txnD-3k2dA:
undetectable		 4txnD-3k2dA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBD_A_TRPA902_0
(PROTEIN ARGONAUTE-2)		 3k2d ABC-TYPE METAL ION
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Vibrio
vulnificus) 		4 / 4 VAL A  70
ALA A  74
PHE A  86
PHE A  66
 None
None
MET  A 266 (-4.9A)
None
 1.33A 6cbdA-3k2dA:
undetectable		 6cbdA-3k2dA:
13.36