SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3k2p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F84_A_SAMA501_0
(GERANYL DIPHOSPHATE
2-C-METHYLTRANSFERAS
E)		 3k2p REVERSE
TRANSCRIPTASE
(Human
immunodeficiency
virus
1) 		5 / 12 GLY A 490
VAL A 531
LEU A 486
TYR A 457
VAL A 442
 None
 1.18A 4f84A-3k2pA:
2.1		 4f84A-3k2pA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE3_B_CL6B502_1
(CYTOCHROME P-450)		 3k2p REVERSE
TRANSCRIPTASE
(Human
immunodeficiency
virus
1) 		4 / 5 LEU A 517
ALA A 502
THR A 497
ILE A 495
 None
 0.90A 4xe3B-3k2pA:
undetectable		 4xe3B-3k2pA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_1
(CYTOCHROME P450 1A1)		 3k2p REVERSE
TRANSCRIPTASE
(Human
immunodeficiency
virus
1) 		3 / 3 SER A 513
SER A 515
ALA A 502
 None
 0.73A 6dwnC-3k2pA:
undetectable		 6dwnC-3k2pA:
20.00