SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3k2v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_1
(DNA TOPOISOMERASE II)		 3k2v PUTATIVE D-ARABINOSE
5-PHOSPHATE
ISOMERASE
(Klebsiella
pneumoniae) 		4 / 7 HIS A 326
THR A 309
LEU A 300
GLN A 304
 None
 1.05A 1qzrA-3k2vA:
undetectable		 1qzrA-3k2vA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_2
(DNA TOPOISOMERASE II)		 3k2v PUTATIVE D-ARABINOSE
5-PHOSPHATE
ISOMERASE
(Klebsiella
pneumoniae) 		4 / 7 HIS A 326
THR A 309
LEU A 300
GLN A 304
 None
 1.05A 1qzrB-3k2vA:
undetectable		 1qzrB-3k2vA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_A_ACTA1117_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3k2v PUTATIVE D-ARABINOSE
5-PHOSPHATE
ISOMERASE
(Klebsiella
pneumoniae) 		3 / 3 ASP A 276
ARG A 232
ARG A 275
 None
 1.06A 2j9dA-3k2vA:
undetectable
2j9dC-3k2vA:
undetectable		 2j9dA-3k2vA:
23.53
2j9dC-3k2vA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZU_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3k2v PUTATIVE D-ARABINOSE
5-PHOSPHATE
ISOMERASE
(Klebsiella
pneumoniae) 		5 / 12 ILE A 238
ALA A 234
ILE A 258
CYH A 310
HIS A 324
 None
None
CMK  A   1 (-4.2A)
CMK  A   1 (-3.7A)
GOL  A 333 (-4.8A)
 1.14A 3dzuA-3k2vA:
undetectable		 3dzuA-3k2vA:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3k2v PUTATIVE D-ARABINOSE
5-PHOSPHATE
ISOMERASE
(Klebsiella
pneumoniae) 		5 / 12 ILE A 258
THR A 260
ASP A 263
THR A 284
ILE A 288
 CMK  A   1 (-4.2A)
CMK  A   1 (-3.4A)
CMK  A   1 (-2.8A)
CMK  A   1 (-3.1A)
CMK  A   1 (-3.7A)
 0.96A 3kpbA-3k2vA:
15.6		 3kpbA-3k2vA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3k2v PUTATIVE D-ARABINOSE
5-PHOSPHATE
ISOMERASE
(Klebsiella
pneumoniae) 		6 / 12 ILE A 258
THR A 260
ASP A 263
THR A 284
ILE A 288
ILE A 308
 CMK  A   1 (-4.2A)
CMK  A   1 (-3.4A)
CMK  A   1 (-2.8A)
CMK  A   1 (-3.1A)
CMK  A   1 (-3.7A)
CMK  A   1 (-3.7A)
 0.79A 3kpbA-3k2vA:
15.6		 3kpbA-3k2vA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3k2v PUTATIVE D-ARABINOSE
5-PHOSPHATE
ISOMERASE
(Klebsiella
pneumoniae) 		5 / 12 ILE A 258
THR A 260
ASP A 263
THR A 284
ILE A 288
 CMK  A   1 (-4.2A)
CMK  A   1 (-3.4A)
CMK  A   1 (-2.8A)
CMK  A   1 (-3.1A)
CMK  A   1 (-3.7A)
 0.96A 3kpbC-3k2vA:
15.6		 3kpbC-3k2vA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3k2v PUTATIVE D-ARABINOSE
5-PHOSPHATE
ISOMERASE
(Klebsiella
pneumoniae) 		6 / 12 ILE A 258
THR A 260
ASP A 263
THR A 284
ILE A 288
ILE A 308
 CMK  A   1 (-4.2A)
CMK  A   1 (-3.4A)
CMK  A   1 (-2.8A)
CMK  A   1 (-3.1A)
CMK  A   1 (-3.7A)
CMK  A   1 (-3.7A)
 0.79A 3kpbC-3k2vA:
15.6		 3kpbC-3k2vA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_D_SAMD1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3k2v PUTATIVE D-ARABINOSE
5-PHOSPHATE
ISOMERASE
(Klebsiella
pneumoniae) 		5 / 10 ILE A 258
THR A 260
ASP A 263
THR A 284
ILE A 288
 CMK  A   1 (-4.2A)
CMK  A   1 (-3.4A)
CMK  A   1 (-2.8A)
CMK  A   1 (-3.1A)
CMK  A   1 (-3.7A)
 0.95A 3kpbD-3k2vA:
15.4		 3kpbD-3k2vA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_D_SAMD1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3k2v PUTATIVE D-ARABINOSE
5-PHOSPHATE
ISOMERASE
(Klebsiella
pneumoniae) 		6 / 10 ILE A 258
THR A 260
ASP A 263
THR A 284
ILE A 288
ILE A 308
 CMK  A   1 (-4.2A)
CMK  A   1 (-3.4A)
CMK  A   1 (-2.8A)
CMK  A   1 (-3.1A)
CMK  A   1 (-3.7A)
CMK  A   1 (-3.7A)
 0.83A 3kpbD-3k2vA:
15.4		 3kpbD-3k2vA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPC_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3k2v PUTATIVE D-ARABINOSE
5-PHOSPHATE
ISOMERASE
(Klebsiella
pneumoniae) 		5 / 11 ILE A 258
THR A 260
ASP A 263
THR A 284
ILE A 288
 CMK  A   1 (-4.2A)
CMK  A   1 (-3.4A)
CMK  A   1 (-2.8A)
CMK  A   1 (-3.1A)
CMK  A   1 (-3.7A)
 1.09A 3kpcA-3k2vA:
16.5		 3kpcA-3k2vA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3k2v PUTATIVE D-ARABINOSE
5-PHOSPHATE
ISOMERASE
(Klebsiella
pneumoniae) 		5 / 12 ILE A 258
THR A 260
ASP A 263
THR A 284
ILE A 288
 CMK  A   1 (-4.2A)
CMK  A   1 (-3.4A)
CMK  A   1 (-2.8A)
CMK  A   1 (-3.1A)
CMK  A   1 (-3.7A)
 0.97A 3kpdB-3k2vA:
15.4		 3kpdB-3k2vA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3k2v PUTATIVE D-ARABINOSE
5-PHOSPHATE
ISOMERASE
(Klebsiella
pneumoniae) 		5 / 12 ILE A 258
THR A 260
ASP A 263
THR A 284
ILE A 308
 CMK  A   1 (-4.2A)
CMK  A   1 (-3.4A)
CMK  A   1 (-2.8A)
CMK  A   1 (-3.1A)
CMK  A   1 (-3.7A)
 0.83A 3kpdB-3k2vA:
15.4		 3kpdB-3k2vA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3k2v PUTATIVE D-ARABINOSE
5-PHOSPHATE
ISOMERASE
(Klebsiella
pneumoniae) 		5 / 12 ILE A 258
THR A 260
THR A 284
ILE A 288
ILE A 308
 CMK  A   1 (-4.2A)
CMK  A   1 (-3.4A)
CMK  A   1 (-3.1A)
CMK  A   1 (-3.7A)
CMK  A   1 (-3.7A)
 0.89A 3kpdB-3k2vA:
15.4		 3kpdB-3k2vA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 3k2v PUTATIVE D-ARABINOSE
5-PHOSPHATE
ISOMERASE
(Klebsiella
pneumoniae) 		6 / 12 ILE A 258
THR A 260
ASP A 263
THR A 284
ILE A 288
VAL A 311
 CMK  A   1 (-4.2A)
CMK  A   1 (-3.4A)
CMK  A   1 (-2.8A)
CMK  A   1 (-3.1A)
CMK  A   1 (-3.7A)
CMK  A   1 (-4.3A)
 1.43A 3kpdC-3k2vA:
16.3		 3kpdC-3k2vA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 3k2v PUTATIVE D-ARABINOSE
5-PHOSPHATE
ISOMERASE
(Klebsiella
pneumoniae) 		6 / 12 ILE A 258
THR A 260
ASP A 263
THR A 284
ILE A 308
VAL A 311
 CMK  A   1 (-4.2A)
CMK  A   1 (-3.4A)
CMK  A   1 (-2.8A)
CMK  A   1 (-3.1A)
CMK  A   1 (-3.7A)
CMK  A   1 (-4.3A)
 0.95A 3kpdC-3k2vA:
16.3		 3kpdC-3k2vA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 3k2v PUTATIVE D-ARABINOSE
5-PHOSPHATE
ISOMERASE
(Klebsiella
pneumoniae) 		6 / 12 ILE A 258
THR A 260
THR A 284
ILE A 288
ILE A 308
VAL A 311
 CMK  A   1 (-4.2A)
CMK  A   1 (-3.4A)
CMK  A   1 (-3.1A)
CMK  A   1 (-3.7A)
CMK  A   1 (-3.7A)
CMK  A   1 (-4.3A)
 1.01A 3kpdC-3k2vA:
16.3		 3kpdC-3k2vA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_A_D16A520_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3k2v PUTATIVE D-ARABINOSE
5-PHOSPHATE
ISOMERASE
(Klebsiella
pneumoniae) 		5 / 12 THR A 218
ILE A 222
PRO A 223
LEU A 320
THR A 294
 None
 0.96A 3nrrA-3k2vA:
undetectable		 3nrrA-3k2vA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_B_D16B520_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3k2v PUTATIVE D-ARABINOSE
5-PHOSPHATE
ISOMERASE
(Klebsiella
pneumoniae) 		5 / 12 THR A 218
ILE A 222
PRO A 223
LEU A 320
THR A 294
 None
 0.96A 3nrrB-3k2vA:
undetectable		 3nrrB-3k2vA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_A_C2FA1100_1
(GLYCINE
N-METHYLTRANSFERASE)		 3k2v PUTATIVE D-ARABINOSE
5-PHOSPHATE
ISOMERASE
(Klebsiella
pneumoniae) 		3 / 3 LEU A 319
HIS A 318
MET A 253
 None
 0.96A 3thrD-3k2vA:
undetectable		 3thrD-3k2vA:
22.30