SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3k2w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DF7_A_MTXA501_2
(DIHYDROFOLATE
REDUCTASE)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		3 / 3 TRP A  64
ARG A 165
THR A 173
 None
 0.97A 1df7A-3k2wA:
undetectable		 1df7A-3k2wA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E06_B_IPBB600_0
(ODORANT-BINDING
PROTEIN)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		4 / 4 ILE A  30
MET A  93
VAL A 208
GLY A  40
 None
 1.29A 1e06B-3k2wA:
undetectable		 1e06B-3k2wA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		4 / 7 THR A 189
GLY A 164
THR A 112
ILE A 116
 None
 0.96A 1gtnF-3k2wA:
undetectable
1gtnG-3k2wA:
undetectable		 1gtnF-3k2wA:
10.75
1gtnG-3k2wA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		4 / 7 THR A 189
GLY A 164
THR A 112
ILE A 116
 None
 0.96A 1gtnJ-3k2wA:
undetectable
1gtnK-3k2wA:
undetectable		 1gtnJ-3k2wA:
10.75
1gtnK-3k2wA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_D_RBFD504_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		5 / 12 ILE A 337
HIS A 342
GLY A 358
LEU A 377
ILE A 395
 None
 1.08A 1kyvC-3k2wA:
2.5
1kyvD-3k2wA:
3.2		 1kyvC-3k2wA:
17.11
1kyvD-3k2wA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_E_RBFE505_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		5 / 12 ILE A 337
HIS A 342
GLY A 358
LEU A 377
ILE A 395
 None
 1.06A 1kyvD-3k2wA:
3.2
1kyvE-3k2wA:
3.2		 1kyvD-3k2wA:
17.11
1kyvE-3k2wA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_A_IMNA379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		5 / 12 CYH A 285
PRO A 394
PRO A 321
VAL A 313
LEU A 278
 None
 1.41A 1z9hA-3k2wA:
undetectable		 1z9hA-3k2wA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_B_IMNB381_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		5 / 12 CYH A 285
PRO A 394
PRO A 321
VAL A 313
LEU A 278
 None
 1.42A 1z9hB-3k2wA:
undetectable		 1z9hB-3k2wA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_C_IMNC379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		5 / 12 CYH A 285
PRO A 394
PRO A 321
VAL A 313
LEU A 278
 None
 1.41A 1z9hC-3k2wA:
undetectable		 1z9hC-3k2wA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9W_A_PAUA6002_0
(PANTOTHENATE KINASE)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		4 / 8 THR A 173
GLY A 119
THR A 125
ILE A 126
 None
None
None
GOL  A 496 ( 3.8A)
 0.62A 2f9wA-3k2wA:
undetectable
2f9wB-3k2wA:
undetectable		 2f9wA-3k2wA:
19.92
2f9wB-3k2wA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXD_A_DR7A102_1
(POL PROTEIN)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		5 / 11 ILE A 172
LEU A  76
GLY A 200
ALA A 199
GLY A 193
 GOL  A 496 (-4.7A)
None
None
None
None
 1.08A 2fxdA-3k2wA:
undetectable		 2fxdA-3k2wA:
10.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_D_STID600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		6 / 12 ALA A 161
ILE A 167
THR A 112
PHE A 158
LEU A  94
ALA A 188
 None
 1.39A 2hyyD-3k2wA:
undetectable		 2hyyD-3k2wA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_C_SC2C1289_1
(FICOLIN-2)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		4 / 6 SER A 414
SER A 462
LEU A 418
GLY A 417
 None
CL  A 497 ( 4.4A)
CL  A 497 (-4.9A)
CL  A 497 ( 4.0A)
 0.90A 2j2pA-3k2wA:
undetectable
2j2pC-3k2wA:
undetectable		 2j2pA-3k2wA:
18.76
2j2pC-3k2wA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1289_1
(FICOLIN-2)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		4 / 6 SER A 414
SER A 462
LEU A 418
GLY A 417
 None
CL  A 497 ( 4.4A)
CL  A 497 (-4.9A)
CL  A 497 ( 4.0A)
 0.89A 2j2pD-3k2wA:
undetectable
2j2pF-3k2wA:
undetectable		 2j2pD-3k2wA:
18.76
2j2pF-3k2wA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB928_0
(FERROCHELATASE)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		5 / 12 LEU A  94
GLN A 287
LEU A 179
PRO A 181
VAL A 208
 None
 1.38A 2qd4B-3k2wA:
undetectable		 2qd4B-3k2wA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_1
(PROTEASE RETROPEPSIN)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		5 / 12 LEU A  76
GLY A 200
ALA A 199
ILE A  83
GLY A 193
 None
 0.87A 2rkfA-3k2wA:
undetectable		 2rkfA-3k2wA:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_1
(PROTEASE RETROPEPSIN)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		5 / 12 LEU A  76
GLY A 200
ALA A 199
ILE A  83
GLY A 193
 None
 0.78A 2rkgA-3k2wA:
undetectable		 2rkgA-3k2wA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_F_TOPF1159_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		5 / 10 ILE A 116
ALA A 163
LEU A  90
ILE A  83
PHE A  79
 None
 1.23A 2w9sF-3k2wA:
undetectable		 2w9sF-3k2wA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_C_SAMC530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		3 / 3 TYR A 416
GLU A 390
ASN A 157
 None
 1.04A 2y7hC-3k2wA:
undetectable		 2y7hC-3k2wA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_B_VD3B700_1
(CYTOCHROME P450 2R1)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		5 / 12 ASN A 284
ALA A 161
ALA A  91
THR A 182
THR A 154
 None
 1.12A 3c6gB-3k2wA:
undetectable		 3c6gB-3k2wA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_A_D2VA602_1
(CYTOCHROME P450 2R1)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		5 / 12 ASN A 284
ALA A 161
ALA A  91
THR A 182
THR A 154
 None
 1.14A 3czhA-3k2wA:
undetectable		 3czhA-3k2wA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_B_D2VB602_1
(CYTOCHROME P450 2R1)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		5 / 12 ASN A 284
ALA A 161
ALA A  91
THR A 182
THR A 154
 None
 1.14A 3czhB-3k2wA:
undetectable		 3czhB-3k2wA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_B_V2HB602_0
(CYTOCHROME P450 2R1)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		5 / 12 ASN A 284
ALA A 161
ALA A  91
THR A 182
THR A 154
 None
 1.14A 3dl9B-3k2wA:
undetectable		 3dl9B-3k2wA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEO_A_SAMA328_1
(MODIFICATION
METHYLASE HHAI)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		3 / 3 GLU A 336
SER A 234
VAL A 236
 None
 0.80A 3eeoA-3k2wA:
undetectable		 3eeoA-3k2wA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LP9_D_SPMD230_1
(LS-24)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		3 / 3 GLU A 389
GLU A 336
ASN A 339
 None
 0.90A 3lp9B-3k2wA:
undetectable
3lp9D-3k2wA:
undetectable		 3lp9B-3k2wA:
18.14
3lp9D-3k2wA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_2
(PROTEASE)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		5 / 9 LEU A  76
GLY A 200
ALA A 199
ILE A  83
GLY A 193
 None
 0.89A 3nu4B-3k2wA:
undetectable		 3nu4B-3k2wA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_2
(PROTEASE)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		5 / 10 LEU A  76
GLY A 200
ALA A 199
ILE A  83
GLY A 193
 None
 0.89A 3s43B-3k2wA:
undetectable		 3s43B-3k2wA:
11.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SG9_B_KANB305_1
(APH(2'')-ID)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		4 / 8 ASN A 333
SER A 234
GLU A 390
GLU A 293
 None
 1.15A 3sg9B-3k2wA:
undetectable		 3sg9B-3k2wA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_A_9PLA501_1
(CYTOCHROME P450 2A6)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		5 / 10 VAL A 208
ALA A 163
THR A 112
ILE A  83
PHE A  79
 None
 1.07A 3t3qA-3k2wA:
undetectable		 3t3qA-3k2wA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_B_9PLB501_1
(CYTOCHROME P450 2A6)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		5 / 10 VAL A 208
ALA A 163
THR A 112
ILE A  83
PHE A  79
 None
 1.08A 3t3qB-3k2wA:
undetectable		 3t3qB-3k2wA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_C_9PLC501_1
(CYTOCHROME P450 2A6)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		5 / 10 VAL A 208
ALA A 163
THR A 112
ILE A  83
PHE A  79
 None
 1.07A 3t3qC-3k2wA:
undetectable		 3t3qC-3k2wA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_D_9PLD501_1
(CYTOCHROME P450 2A6)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		5 / 10 VAL A 208
ALA A 163
THR A 112
ILE A  83
PHE A  79
 None
 1.10A 3t3qD-3k2wA:
undetectable		 3t3qD-3k2wA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		4 / 5 THR A 230
GLY A 152
VAL A 178
TYR A 476
 None
 1.08A 4grkA-3k2wA:
undetectable		 4grkA-3k2wA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOU_A_C04A207_1
(UNCHARACTERIZED
PROTEIN)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		3 / 3 GLY A 286
GLU A 390
THR A 391
 None
 0.53A 4kouA-3k2wA:
undetectable		 4kouA-3k2wA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA301_1
(CHITOSANASE)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		4 / 4 ASP A 320
GLY A 329
PRO A 330
GLN A  98
 None
 1.28A 4oltA-3k2wA:
0.4		 4oltA-3k2wA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB301_1
(CHITOSANASE)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		3 / 3 GLY A 329
PRO A 330
GLN A 287
 None
 0.44A 4oltB-3k2wA:
undetectable		 4oltB-3k2wA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1Y_A_017A106_1
(ASPARTYL PROTEASE)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		5 / 10 LEU A  76
GLY A 200
ALA A 199
ILE A  83
GLY A 193
 None
 0.95A 4q1yA-3k2wA:
undetectable		 4q1yA-3k2wA:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB305_1
(CHITOSANASE)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		3 / 3 GLY A 329
PRO A 330
GLN A 287
 None
 0.33A 4qwpB-3k2wA:
undetectable		 4qwpB-3k2wA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YFB_C_PACC601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		5 / 12 SER A  22
PRO A  43
GLN A 183
ILE A  42
VAL A 216
 None
 1.47A 4yfbC-3k2wA:
undetectable		 4yfbC-3k2wA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YFB_F_PACF601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		5 / 12 SER A  22
PRO A  43
GLN A 183
ILE A  42
VAL A 216
 None
 1.48A 4yfbF-3k2wA:
undetectable		 4yfbF-3k2wA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YFB_I_PACI601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		5 / 12 SER A  22
PRO A  43
GLN A 183
ILE A  42
VAL A 216
 None
 1.47A 4yfbI-3k2wA:
undetectable		 4yfbI-3k2wA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YFB_L_PACL601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		5 / 12 SER A  22
PRO A  43
GLN A 183
ILE A  42
VAL A 216
 None
 1.47A 4yfbL-3k2wA:
undetectable		 4yfbL-3k2wA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_A_ACTA703_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		4 / 6 ARG A 165
ALA A 155
PHE A 158
GLU A 108
 None
 1.40A 5odqA-3k2wA:
2.3		 5odqA-3k2wA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_B_RFPB502_2
(RIFAMPIN
MONOOXYGENASE)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		4 / 6 GLN A 327
LEU A 278
ARG A 281
PRO A 374
 None
 1.28A 6brdB-3k2wA:
undetectable		 6brdB-3k2wA:
9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G2P_A_TRPA502_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		4 / 7 HIS A 345
LEU A 377
TYR A 372
VAL A 354
 None
 1.35A 6g2pA-3k2wA:
undetectable		 6g2pA-3k2wA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NM4_A_SAMA402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9)		 3k2w BETAINE-ALDEHYDE
DEHYDROGENASE
(Pseudoalteromona
s
atlantica) 		4 / 7 GLY A 258
LEU A 418
TYR A 421
CYH A 411
 CL  A 497 ( 3.8A)
CL  A 497 (-4.9A)
None
None
 0.82A 6nm4A-3k2wA:
undetectable		 6nm4A-3k2wA:
17.90