SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3k32'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_B_HSMB402_1
(NITROPHORIN 1)		 3k32 UNCHARACTERIZED
PROTEIN MJ0690
(Methanocaldococc
us
jannaschii) 		4 / 5 ASP A  15
THR A 142
LEU A 146
LEU A 143
 None
 1.20A 1u18B-3k32A:
undetectable		 1u18B-3k32A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOC_C_ERYC3402_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3k32 UNCHARACTERIZED
PROTEIN MJ0690
(Methanocaldococc
us
jannaschii) 		3 / 3 THR A 191
SER A 148
LYS A 197
 None
 1.18A 3aocC-3k32A:
undetectable		 3aocC-3k32A:
12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EIG_A_MTXA200_2
(DIHYDROFOLATE
REDUCTASE)		 3k32 UNCHARACTERIZED
PROTEIN MJ0690
(Methanocaldococc
us
jannaschii) 		4 / 5 ASP A 165
ARG A 171
ILE A 170
VAL A  39
 None
 0.94A 3eigA-3k32A:
undetectable		 3eigA-3k32A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F3T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3k32 UNCHARACTERIZED
PROTEIN MJ0690
(Methanocaldococc
us
jannaschii) 		4 / 6 LEU A  92
LEU A 123
GLU A 124
TYR A 131
 None
 1.07A 4f3tA-3k32A:
2.5		 4f3tA-3k32A:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_A_ACTA401_0
(PROTON-GATED ION
CHANNEL)		 3k32 UNCHARACTERIZED
PROTEIN MJ0690
(Methanocaldococc
us
jannaschii) 		4 / 6 ILE A  40
ARG A  64
ILE A 173
GLU A 176
 None
 1.36A 4zzcA-3k32A:
undetectable
4zzcB-3k32A:
undetectable		 4zzcA-3k32A:
21.27
4zzcB-3k32A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_B_ACTB401_0
(PROTON-GATED ION
CHANNEL)		 3k32 UNCHARACTERIZED
PROTEIN MJ0690
(Methanocaldococc
us
jannaschii) 		4 / 6 ILE A  40
ARG A  64
ILE A 173
GLU A 176
 None
 1.39A 4zzcB-3k32A:
undetectable
4zzcC-3k32A:
undetectable		 4zzcB-3k32A:
21.27
4zzcC-3k32A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_C_FUAC1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3k32 UNCHARACTERIZED
PROTEIN MJ0690
(Methanocaldococc
us
jannaschii) 		3 / 3 VAL A  67
HIS A  88
VAL A  91
 None
 0.70A 5jmnC-3k32A:
undetectable		 5jmnC-3k32A:
12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_1
(REGULATORY PROTEIN
TETR)		 3k32 UNCHARACTERIZED
PROTEIN MJ0690
(Methanocaldococc
us
jannaschii) 		4 / 7 GLY A 105
GLN A 190
ASP A 165
TYR A 166
 None
 1.24A 5vlmG-3k32A:
undetectable		 5vlmG-3k32A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_E_D16E402_1
(THYMIDYLATE SYNTHASE)		 3k32 UNCHARACTERIZED
PROTEIN MJ0690
(Methanocaldococc
us
jannaschii) 		4 / 6 PHE A 138
ILE A  22
ASP A 104
GLY A 105
 None
 0.82A 5x5qE-3k32A:
undetectable		 5x5qE-3k32A:
21.09