SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3k33'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y0X_X_T44X500_2
(THYROID HORMONE
RECEPTOR BETA-1)		 3k33 DEATH ON CURING
PROTEIN
(Escherichia
virus
P1) 		4 / 5 SER A  79
ARG A  86
LEU A  84
ASN A  87
 None
 1.16A 1y0xX-3k33A:
undetectable		 1y0xX-3k33A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3k33 DEATH ON CURING
PROTEIN
(Escherichia
virus
P1) 		5 / 12 LEU A   9
GLY A  65
SER A  27
ALA A  63
ALA A 104
 None
 0.95A 2bm9A-3k33A:
undetectable		 2bm9A-3k33A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3k33 DEATH ON CURING
PROTEIN
(Escherichia
virus
P1) 		5 / 12 LEU A   9
GLY A  65
SER A  27
ALA A  63
ALA A 104
 None
 0.98A 2bm9D-3k33A:
undetectable		 2bm9D-3k33A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3k33 DEATH ON CURING
PROTEIN
(Escherichia
virus
P1) 		5 / 12 LEU A   9
GLY A  65
SER A  27
ALA A  63
ALA A 104
 None
 1.12A 2br4A-3k33A:
undetectable		 2br4A-3k33A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NPN_A_SAMA4633_0
(PUTATIVE COBALAMIN
SYNTHESIS RELATED
PROTEIN)		 3k33 DEATH ON CURING
PROTEIN
(Escherichia
virus
P1) 		5 / 9 THR A  62
THR A  75
ALA A  76
LEU A  59
THR A 101
 None
 1.25A 2npnA-3k33A:
undetectable		 2npnA-3k33A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1498_1
(CYTOCHROME P450 3A4)		 3k33 DEATH ON CURING
PROTEIN
(Escherichia
virus
P1) 		5 / 12 PHE A  68
ILE A  35
ALA A  61
THR A  57
ARG A   2
 None
 1.27A 2v0mC-3k33A:
undetectable		 2v0mC-3k33A:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PS9_A_SAMA670_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 3k33 DEATH ON CURING
PROTEIN
(Escherichia
virus
P1) 		5 / 12 GLU A  33
ASP A  14
ILE A  10
GLY A  30
MET A  26
 None
 1.38A 3ps9A-3k33A:
undetectable		 3ps9A-3k33A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_2
(ADENOSINE KINASE)		 3k33 DEATH ON CURING
PROTEIN
(Escherichia
virus
P1) 		4 / 5 LEU A  81
SER A  79
LEU A 118
ASN A  16
 None
 1.15A 4n09B-3k33A:
undetectable		 4n09B-3k33A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJB_A_198A1001_2
(ANDROGEN RECEPTOR)		 3k33 DEATH ON CURING
PROTEIN
(Escherichia
virus
P1) 		4 / 7 LEU A  59
ILE A  35
ILE A  36
VAL A  39
 None
 0.71A 4ojbA-3k33A:
undetectable		 4ojbA-3k33A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 3k33 DEATH ON CURING
PROTEIN
(Escherichia
virus
P1) 		5 / 10 ALA A  76
THR A  75
SER A  79
GLY A  65
ALA A  61
 None
 1.12A 5l66K-3k33A:
undetectable
5l66L-3k33A:
undetectable		 5l66K-3k33A:
20.40
5l66L-3k33A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 3k33 DEATH ON CURING
PROTEIN
(Escherichia
virus
P1) 		5 / 10 ALA A  76
THR A  75
SER A  79
GLY A  65
ALA A  61
 None
 1.13A 5l66Y-3k33A:
undetectable
5l66Z-3k33A:
undetectable		 5l66Y-3k33A:
20.40
5l66Z-3k33A:
22.22