SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3k3d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_C_DVAC6_0
(GRAMICIDIN A)		 3k3d PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		3 / 3 ALA A  13
VAL A  11
TRP A   7
 None
 0.88A 1av2C-3k3dA:
undetectable
1av2D-3k3dA:
undetectable		 1av2C-3k3dA:
13.58
1av2D-3k3dA:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_C_DVAC6_0
(GRAMICIDIN D)		 3k3d PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		3 / 3 ALA A  13
VAL A  11
TRP A   7
 None
 0.82A 1w5uC-3k3dA:
undetectable
1w5uD-3k3dA:
undetectable		 1w5uC-3k3dA:
13.58
1w5uD-3k3dA:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_B_DVAB6_0
(GRAMICIDIN D)		 3k3d PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		3 / 3 TRP A   7
ALA A  13
VAL A  11
 None
 0.71A 2izqA-3k3dA:
undetectable
2izqB-3k3dA:
undetectable		 2izqA-3k3dA:
13.58
2izqB-3k3dA:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_A_DVAA6_0
(GRAMICIDIN D)		 3k3d PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		3 / 3 ALA A  13
VAL A  11
TRP A   7
 None
 0.69A 3l8lA-3k3dA:
undetectable
3l8lB-3k3dA:
undetectable		 3l8lA-3k3dA:
13.58
3l8lB-3k3dA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_C_DVAC6_0
(GRAMICIDIN D)		 3k3d PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		3 / 3 ALA A  13
VAL A  11
TRP A   7
 None
 0.79A 3l8lC-3k3dA:
undetectable
3l8lD-3k3dA:
undetectable		 3l8lC-3k3dA:
13.58
3l8lD-3k3dA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B3Q_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 3k3d PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		4 / 7 LEU A  31
VAL A  78
TYR A  72
LEU A 125
 None
 0.98A 4b3qA-3k3dA:
undetectable		 4b3qA-3k3dA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_A_ILEA601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3k3d PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		4 / 6 VAL A  62
TYR A  63
VAL A  29
HIS A  36
 None
 0.87A 5eckA-3k3dA:
undetectable		 5eckA-3k3dA:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_D_ILED601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3k3d PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		4 / 6 VAL A  62
TYR A  63
VAL A  29
HIS A  36
 None
 0.90A 5eckD-3k3dA:
undetectable		 5eckD-3k3dA:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_A_ILEA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3k3d PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		4 / 6 VAL A  62
TYR A  63
VAL A  29
HIS A  36
 None
 0.93A 5eclA-3k3dA:
undetectable		 5eclA-3k3dA:
14.59