SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3k44'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VIF_A_FOLA1_0
(DIHYDROFOLATE
REDUCTASE)		 3k44 PURINE-RICH BINDING
PROTEIN-ALPHA,
ISOFORM B
(Drosophila
melanogaster) 		3 / 3 GLN A  82
ILE A  83
TYR A  84
 None
 0.68A 1vifA-3k44A:
undetectable		 1vifA-3k44A:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRB_X_TOPX300_1
(DIHYDROFOLATE
REDUCTASE)		 3k44 PURINE-RICH BINDING
PROTEIN-ALPHA,
ISOFORM B
(Drosophila
melanogaster) 		5 / 11 LEU A  97
ALA A 174
LEU A  58
ILE A  83
PHE A  93
 None
 1.11A 3frbX-3k44A:
undetectable		 3frbX-3k44A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG305_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3k44 PURINE-RICH BINDING
PROTEIN-ALPHA,
ISOFORM B
(Drosophila
melanogaster) 		3 / 3 ASP A 118
ARG A 147
LYS A 120
 EDO  A3318 (-3.1A)
None
EDO  A3318 (-4.2A)
 1.26A 3wipG-3k44A:
undetectable		 3wipG-3k44A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B53_B_ACTB1445_0
(IG GAMMA-4 CHAIN C
REGION)		 3k44 PURINE-RICH BINDING
PROTEIN-ALPHA,
ISOFORM B
(Drosophila
melanogaster) 		3 / 3 GLU A  73
GLY A  75
SER A  81
 None
 0.62A 4b53B-3k44A:
undetectable		 4b53B-3k44A:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_A_CXQA507_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 3k44 PURINE-RICH BINDING
PROTEIN-ALPHA,
ISOFORM B
(Drosophila
melanogaster) 		4 / 5 ARG A 147
ALA A 162
GLN A 160
ILE A  83
 None
 1.28A 6f6sA-3k44A:
undetectable
6f6sB-3k44A:
0.0		 6f6sA-3k44A:
21.38
6f6sB-3k44A:
20.71