SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3k4w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_A_DVAA6_0
(GRAMICIDIN A)		 3k4w UNCHARACTERIZED
PROTEIN BB4693
(Bordetella
bronchiseptica) 		3 / 3 ALA A 128
VAL A 126
TRP A 127
 None
 0.67A 1bdwA-3k4wA:
undetectable
1bdwB-3k4wA:
undetectable		 1bdwA-3k4wA:
6.32
1bdwB-3k4wA:
6.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOB_A_PNNA1311_1
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 3k4w UNCHARACTERIZED
PROTEIN BB4693
(Bordetella
bronchiseptica) 		3 / 3 ARG A 203
ARG A 204
ILE A 197
 None
 0.74A 1uobA-3k4wA:
undetectable		 1uobA-3k4wA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_1
(ANDROGEN RECEPTOR)		 3k4w UNCHARACTERIZED
PROTEIN BB4693
(Bordetella
bronchiseptica) 		5 / 12 ASN A 148
GLY A 149
GLN A 278
VAL A 184
ALA A 143
 None
 1.12A 2oz7A-3k4wA:
undetectable		 2oz7A-3k4wA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_A_ASDA1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3k4w UNCHARACTERIZED
PROTEIN BB4693
(Bordetella
bronchiseptica) 		4 / 7 PRO A 151
ALA A 279
LEU A 275
PHE A   6
 None
 0.94A 2vcvA-3k4wA:
undetectable		 2vcvA-3k4wA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_2
(BETA-1 ADRENERGIC
RECEPTOR)		 3k4w UNCHARACTERIZED
PROTEIN BB4693
(Bordetella
bronchiseptica) 		3 / 3 VAL A 133
ASN A 190
TRP A 193
 None
 1.02A 2y00B-3k4wA:
undetectable		 2y00B-3k4wA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3k4w UNCHARACTERIZED
PROTEIN BB4693
(Bordetella
bronchiseptica) 		3 / 3 VAL A  94
VAL A 185
SER A 187
 None
 0.69A 3n8xB-3k4wA:
undetectable		 3n8xB-3k4wA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB6_C_VLBC503_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 3k4w UNCHARACTERIZED
PROTEIN BB4693
(Bordetella
bronchiseptica) 		5 / 12 VAL A  83
PRO A  88
ILE A 119
VAL A  63
ILE A   4
 None
 1.45A 4eb6B-3k4wA:
undetectable
4eb6C-3k4wA:
undetectable		 4eb6B-3k4wA:
19.46
4eb6C-3k4wA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3k4w UNCHARACTERIZED
PROTEIN BB4693
(Bordetella
bronchiseptica) 		4 / 8 ASN A 121
GLY A  66
VAL A  65
ILE A  20
 None
 0.89A 4fglD-3k4wA:
undetectable		 4fglD-3k4wA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3k4w UNCHARACTERIZED
PROTEIN BB4693
(Bordetella
bronchiseptica) 		4 / 7 ASN A 121
GLY A  66
VAL A  65
ILE A  20
 None
 0.83A 4fglC-3k4wA:
undetectable		 4fglC-3k4wA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6C_A_STRA501_1
(CYTOCHROME P450
MONOOXYGENASE)		 3k4w UNCHARACTERIZED
PROTEIN BB4693
(Bordetella
bronchiseptica) 		5 / 11 ALA A  55
ALA A  56
ALA A  57
THR A 251
LEU A   8
 None
 1.15A 4j6cA-3k4wA:
undetectable		 4j6cA-3k4wA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6C_B_STRB503_1
(CYTOCHROME P450
MONOOXYGENASE)		 3k4w UNCHARACTERIZED
PROTEIN BB4693
(Bordetella
bronchiseptica) 		5 / 10 ALA A  55
ALA A  56
ALA A  57
THR A 251
LEU A   8
 None
 1.13A 4j6cB-3k4wA:
undetectable		 4j6cB-3k4wA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JBT_A_ASDA501_1
(CYTOCHROME P450
MONOOXYGENASE)		 3k4w UNCHARACTERIZED
PROTEIN BB4693
(Bordetella
bronchiseptica) 		5 / 12 ALA A  55
ALA A  56
ALA A  57
THR A 251
LEU A   8
 None
 1.12A 4jbtA-3k4wA:
undetectable		 4jbtA-3k4wA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JBT_B_ASDB502_1
(CYTOCHROME P450
MONOOXYGENASE)		 3k4w UNCHARACTERIZED
PROTEIN BB4693
(Bordetella
bronchiseptica) 		5 / 11 ALA A  55
ALA A  56
ALA A  57
THR A 251
LEU A   8
 None
 1.12A 4jbtB-3k4wA:
undetectable		 4jbtB-3k4wA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3k4w UNCHARACTERIZED
PROTEIN BB4693
(Bordetella
bronchiseptica) 		4 / 8 ASN A  68
ARG A  67
ASN A  77
ILE A 117
 None
 1.04A 4l7iA-3k4wA:
undetectable		 4l7iA-3k4wA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MX0_A_BCZA513_1
(NEURAMINIDASE)		 3k4w UNCHARACTERIZED
PROTEIN BB4693
(Bordetella
bronchiseptica) 		3 / 3 ARG A   9
ASP A 212
ARG A  67
 None
 0.81A 4mx0A-3k4wA:
undetectable		 4mx0A-3k4wA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLF_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3k4w UNCHARACTERIZED
PROTEIN BB4693
(Bordetella
bronchiseptica) 		5 / 11 ASP A   5
PHE A   6
ILE A 119
LEU A 275
THR A 240
 None
 1.15A 4qlfA-3k4wA:
undetectable		 4qlfA-3k4wA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLG_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3k4w UNCHARACTERIZED
PROTEIN BB4693
(Bordetella
bronchiseptica) 		5 / 12 ASP A   5
PHE A   6
ILE A 119
LEU A 275
THR A 240
 None
 1.19A 4qlgA-3k4wA:
undetectable		 4qlgA-3k4wA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RGC_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3k4w UNCHARACTERIZED
PROTEIN BB4693
(Bordetella
bronchiseptica) 		5 / 12 ASP A   5
PHE A   6
ILE A 119
LEU A 275
THR A 240
 None
 1.19A 4rgcA-3k4wA:
undetectable		 4rgcA-3k4wA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_B_C2FB402_1
(THYMIDYLATE SYNTHASE)		 3k4w UNCHARACTERIZED
PROTEIN BB4693
(Bordetella
bronchiseptica) 		3 / 3 ASN A  68
ASP A  79
GLY A  14
 None
 0.66A 5fctB-3k4wA:
undetectable		 5fctB-3k4wA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3k4w UNCHARACTERIZED
PROTEIN BB4693
(Bordetella
bronchiseptica) 		4 / 6 VAL A 133
SER A 186
ARG A   7
PHE A   6
 None
 1.07A 5jw1A-3k4wA:
undetectable		 5jw1A-3k4wA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3k4w UNCHARACTERIZED
PROTEIN BB4693
(Bordetella
bronchiseptica) 		5 / 6 VAL A 133
VAL A 184
SER A 186
ARG A   7
PHE A   6
 None
 1.24A 5jw1B-3k4wA:
undetectable		 5jw1B-3k4wA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 3k4w UNCHARACTERIZED
PROTEIN BB4693
(Bordetella
bronchiseptica) 		4 / 6 TYR A  87
ASP A   5
LEU A   8
GLY A  62
 None
 1.02A 5nooC-3k4wA:
undetectable		 5nooC-3k4wA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6N_A_SREA508_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 3k4w UNCHARACTERIZED
PROTEIN BB4693
(Bordetella
bronchiseptica) 		5 / 10 ILE A   4
VAL A 185
LEU A 237
LEU A 276
LEU A 275
 None
 1.00A 6f6nA-3k4wA:
undetectable
6f6nB-3k4wA:
undetectable		 6f6nA-3k4wA:
14.49
6f6nB-3k4wA:
13.38