SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3k4x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RA2_A_FOLA161_0 (DIHYDROFOLATE REDUCTASE)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	6 / 12	ALA A 476 LEU A 517 PHE A 474 ILE A 494 LEU A 496 ILE A 427	None	1.40A	1ra2A-3k4xA: undetectable	1ra2A-3k4xA: 12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RA2_A_FOLA161_0 (DIHYDROFOLATE REDUCTASE)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	6 / 12	ALA A 743 LEU A 784 PHE A 741 ILE A 761 LEU A 763 ILE A 694	None	1.40A	1ra2A-3k4xA: undetectable	1ra2A-3k4xA: 12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RA8_A_FOLA161_0 (DIHYDROFOLATE REDUCTASE)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	6 / 12	ALA A 476 LEU A 517 PHE A 474 ILE A 494 LEU A 496 ILE A 427	None	1.38A	1ra8A-3k4xA: undetectable	1ra8A-3k4xA: 12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RA8_A_FOLA161_0 (DIHYDROFOLATE REDUCTASE)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	6 / 12	ALA A 743 LEU A 784 PHE A 741 ILE A 761 LEU A 763 ILE A 694	None	1.38A	1ra8A-3k4xA: undetectable	1ra8A-3k4xA: 12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RB2_A_FOLA161_0 (DIHYDROFOLATE REDUCTASE)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	6 / 12	ALA A 743 LEU A 784 PHE A 741 ILE A 761 LEU A 763 ILE A 694	None	1.41A	1rb2A-3k4xA: undetectable	1rb2A-3k4xA: 12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WRL_B_TFPB203_1 (TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	4 / 6	VAL A 23 LEU A 72 PHE A 248 SER A 220	None	0.92A	1wrlB-3k4xA: undetectable	1wrlB-3k4xA: 7.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Z11_C_8MOC501_0 (CYTOCHROME P450, FAMILY 2, SUBFAMILY A, POLYPEPTIDE 6)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	5 / 10	ASN A 159 ILE A 158 ILE A 227 LEU A 229 PHE A 237	None	1.13A	1z11C-3k4xA: undetectable	1z11C-3k4xA: 20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Z11_C_8MOC501_0 (CYTOCHROME P450, FAMILY 2, SUBFAMILY A, POLYPEPTIDE 6)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	5 / 10	ASN A 426 ILE A 425 ILE A 494 LEU A 496 PHE A 504	None	1.13A	1z11C-3k4xA: undetectable	1z11C-3k4xA: 20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CL5_B_SAMB1217_1 (CATECHOL O-METHYLTRANSFERASE)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	4 / 6	SER A 756 SER A 583 GLN A 572 ASP A 774	None	1.33A	2cl5B-3k4xA: undetectable	2cl5B-3k4xA: 14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2D0K_B_FOLB2161_0 (DIHYDROFOLATE REDUCTASE)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	6 / 12	ALA A 209 LEU A 250 PHE A 207 ILE A 227 LEU A 229 ILE A 160	None	1.44A	2d0kB-3k4xA: undetectable	2d0kB-3k4xA: 12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2D0K_B_FOLB2161_0 (DIHYDROFOLATE REDUCTASE)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	6 / 12	ALA A 476 LEU A 517 PHE A 474 ILE A 494 LEU A 496 ILE A 427	None	1.37A	2d0kB-3k4xA: undetectable	2d0kB-3k4xA: 12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2D0K_B_FOLB2161_0 (DIHYDROFOLATE REDUCTASE)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	6 / 12	ALA A 743 LEU A 784 PHE A 741 ILE A 761 LEU A 763 ILE A 694	None	1.37A	2d0kB-3k4xA: undetectable	2d0kB-3k4xA: 12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2LBD_A_REAA500_1 (RETINOIC ACID RECEPTOR GAMMA)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	5 / 12	PHE A 273 LYS A 509 ILE A 302 PHE A 324 LEU A 346	None	1.24A	2lbdA-3k4xA: undetectable	2lbdA-3k4xA: 16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QWX_A_ML1A233_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	4 / 8	ILE A 160 PHE A 237 PHE A 239 ILE A 182	None	0.89A	2qwxA-3k4xA: undetectable 2qwxB-3k4xA: undetectable	2qwxA-3k4xA: 14.67 2qwxB-3k4xA: 14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZVJ_A_SAMA301_1 (CATECHOL O-METHYLTRANSFERASE)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	4 / 6	SER A 756 SER A 583 GLN A 572 ASP A 774	None	1.36A	2zvjA-3k4xA: undetectable	2zvjA-3k4xA: 15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ABK_C_CHDC271_0 (CYTOCHROME C OXIDASE SUBUNIT 3)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	4 / 4	ARG A 224 GLN A 238 PHE A 237 LEU A 139	None	1.20A	3abkC-3k4xA: 0.0	3abkC-3k4xA: 14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ABK_C_CHDC271_0 (CYTOCHROME C OXIDASE SUBUNIT 3)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	4 / 4	ARG A 491 GLN A 505 PHE A 504 LEU A 406	None	1.16A	3abkC-3k4xA: 0.0	3abkC-3k4xA: 14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ABK_C_CHDC271_0 (CYTOCHROME C OXIDASE SUBUNIT 3)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	4 / 4	ARG A 758 GLN A 772 PHE A 771 LEU A 673	None	1.20A	3abkC-3k4xA: 0.0	3abkC-3k4xA: 14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ABL_C_CHDC271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 3)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	4 / 5	ARG A 491 GLN A 505 PHE A 504 LEU A 406	None	1.14A	3ablC-3k4xA: undetectable 3ablJ-3k4xA: undetectable	3ablC-3k4xA: 14.85 3ablJ-3k4xA: 5.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ABL_P_CHDP1271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 3)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	4 / 6	ARG A 491 GLN A 505 PHE A 504 LEU A 406	None	1.15A	3ablP-3k4xA: undetectable 3ablW-3k4xA: undetectable	3ablP-3k4xA: 14.85 3ablW-3k4xA: 5.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CJT_C_SAMC302_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	6 / 12	LEU A 50 VAL A 40 LEU A 47 ILE A 16 LEU A 246 LEU A 221	None	1.48A	3cjtC-3k4xA: undetectable	3cjtC-3k4xA: 15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CJT_C_SAMC302_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	6 / 12	LEU A 584 VAL A 574 LEU A 581 ILE A 550 LEU A 780 LEU A 755	None	1.44A	3cjtC-3k4xA: undetectable	3cjtC-3k4xA: 15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CJT_K_SAMK302_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	5 / 12	LEU A 584 VAL A 574 LEU A 581 LEU A 780 LEU A 755	None	1.43A	3cjtK-3k4xA: undetectable	3cjtK-3k4xA: 15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CJT_O_SAMO302_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	6 / 12	LEU A 584 VAL A 574 LEU A 581 ILE A 550 LEU A 780 LEU A 755	None	1.46A	3cjtO-3k4xA: undetectable	3cjtO-3k4xA: 15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OWX_A_XRAA233_2 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	4 / 5	VAL A 26 PHE A 12 ILE A 15 PHE A 6	None	1.09A	3owxB-3k4xA: undetectable	3owxB-3k4xA: 14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OWX_A_XRAA233_2 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	4 / 5	VAL A 293 PHE A 279 ILE A 282 PHE A 273	None	0.99A	3owxB-3k4xA: undetectable	3owxB-3k4xA: 14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3R55_A_PZAA598_0 (LACTOPEROXIDASE)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	3 / 3	GLU A 318 PHE A 512 GLN A 305	None	0.73A	3r55A-3k4xA: undetectable	3r55A-3k4xA: 21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UVV_A_T3A501_1 (THYROID HORMONE RECEPTOR ALPHA)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	5 / 12	ILE A 15 ILE A 16 LEU A 90 LEU A 101 ILE A 99	None	1.06A	3uvvA-3k4xA: undetectable	3uvvA-3k4xA: 15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UVV_A_T3A501_1 (THYROID HORMONE RECEPTOR ALPHA)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	5 / 12	ILE A 282 ILE A 283 LEU A 357 LEU A 368 ILE A 366	None	1.08A	3uvvA-3k4xA: undetectable	3uvvA-3k4xA: 15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W67_C_VIVC301_0 (ALPHA-TOCOPHEROL TRANSFER PROTEIN)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	5 / 12	ILE A 99 ALA A 37 PHE A 28 ILE A 16 VAL A 48	None	1.15A	3w67C-3k4xA: undetectable	3w67C-3k4xA: 16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4D9H_A_ADNA301_1 (PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	5 / 11	SER A 382 GLY A 178 SER A 177 ASP A 172 VAL A 170	None	1.31A	4d9hA-3k4xA: undetectable	4d9hA-3k4xA: 16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DA6_A_GA2A301_1 (PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	5 / 9	SER A 382 GLY A 178 SER A 177 ASP A 172 VAL A 170	None	1.33A	4da6A-3k4xA: undetectable	4da6A-3k4xA: 16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAN_B_2FAB301_1 (PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	5 / 12	SER A 382 GLY A 178 SER A 177 ASP A 172 VAL A 170	None	1.25A	4danA-3k4xA: undetectable 4danB-3k4xA: undetectable	4danA-3k4xA: 16.43 4danB-3k4xA: 16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EJJ_D_NCTD501_1 (CYTOCHROME P450 2A6)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	4 / 7	PHE A 57 GLY A 244 ILE A 15 LEU A 11	None	0.67A	4ejjD-3k4xA: undetectable	4ejjD-3k4xA: 20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EJJ_D_NCTD501_1 (CYTOCHROME P450 2A6)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	4 / 7	PHE A 324 GLY A 511 ILE A 282 LEU A 278	None	0.72A	4ejjD-3k4xA: undetectable	4ejjD-3k4xA: 20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EJJ_D_NCTD501_1 (CYTOCHROME P450 2A6)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	4 / 7	PHE A 591 GLY A 778 ILE A 549 LEU A 545	None	0.73A	4ejjD-3k4xA: undetectable	4ejjD-3k4xA: 20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FHB_A_FOLA201_0 (DIHYDROFOLATE REDUCTASE)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	6 / 12	ALA A 476 LEU A 517 PHE A 474 ILE A 494 LEU A 496 ILE A 427	None	1.45A	4fhbA-3k4xA: undetectable	4fhbA-3k4xA: 12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4I13_A_FOLA201_0 (DIHYDROFOLATE REDUCTASE)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	6 / 12	ALA A 743 LEU A 784 PHE A 741 ILE A 761 LEU A 763 ILE A 694	None	1.42A	4i13A-3k4xA: undetectable	4i13A-3k4xA: 12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4I1N_A_FOLA201_0 (DIHYDROFOLATE REDUCTASE)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	5 / 11	ALA A 271 LEU A 355 PHE A 279 LYS A 280 LEU A 342	None	1.36A	4i1nA-3k4xA: undetectable	4i1nA-3k4xA: 12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J7X_B_SASB804_1 (SEPIAPTERIN REDUCTASE)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	5 / 12	LEU A 536 PRO A 630 MET A 604 GLY A 603 LEU A 652	None	1.14A	4j7xB-3k4xA: undetectable	4j7xB-3k4xA: 16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K38_B_SAMB504_0 (ANAEROBIC SULFATASE-MATURATING ENZYME)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	5 / 12	PHE A 741 GLU A 677 LEU A 731 ILE A 696 LEU A 739	None	1.47A	4k38B-3k4xA: undetectable	4k38B-3k4xA: 17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K39_A_SAMA504_0 (ANAEROBIC SULFATASE-MATURATING ENZYME)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	5 / 12	PHE A 741 GLU A 677 LEU A 731 ILE A 696 LEU A 739	None	1.33A	4k39A-3k4xA: undetectable	4k39A-3k4xA: 17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NX6_A_FOLA201_0 (DIHYDROFOLATE REDUCTASE)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	6 / 12	ALA A 476 LEU A 517 PHE A 474 ILE A 494 LEU A 496 ILE A 427	None	1.42A	4nx6A-3k4xA: undetectable	4nx6A-3k4xA: 12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NX6_A_FOLA201_0 (DIHYDROFOLATE REDUCTASE)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	6 / 12	ALA A 743 LEU A 784 PHE A 741 ILE A 761 LEU A 763 ILE A 694	None	1.43A	4nx6A-3k4xA: undetectable	4nx6A-3k4xA: 12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NX7_A_FOLA202_0 (DIHYDROFOLATE REDUCTASE)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	6 / 12	ALA A 476 LEU A 517 PHE A 474 ILE A 494 LEU A 496 ILE A 427	None	1.43A	4nx7A-3k4xA: undetectable	4nx7A-3k4xA: 12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NX7_A_FOLA202_0 (DIHYDROFOLATE REDUCTASE)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	6 / 12	ALA A 743 LEU A 784 PHE A 741 ILE A 761 LEU A 763 ILE A 694	None	1.44A	4nx7A-3k4xA: undetectable	4nx7A-3k4xA: 12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4P3R_A_FOLA201_0 (DIHYDROFOLATE REDUCTASE)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	6 / 12	ALA A 476 LEU A 517 PHE A 474 ILE A 494 LEU A 496 ILE A 427	None	1.42A	4p3rA-3k4xA: undetectable	4p3rA-3k4xA: 12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4P3R_A_FOLA201_0 (DIHYDROFOLATE REDUCTASE)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	6 / 12	ALA A 743 LEU A 784 PHE A 741 ILE A 761 LEU A 763 ILE A 694	None	1.43A	4p3rA-3k4xA: undetectable	4p3rA-3k4xA: 12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PST_A_FOLA201_0 (DIHYDROFOLATE REDUCTASE)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	6 / 12	ALA A 476 LEU A 517 PHE A 474 ILE A 494 LEU A 496 ILE A 427	None	1.45A	4pstA-3k4xA: undetectable	4pstA-3k4xA: 12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QOG_A_ML1A302_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	4 / 8	ILE A 160 PHE A 237 PHE A 239 ILE A 182	None	0.82A	4qogA-3k4xA: undetectable 4qogB-3k4xA: undetectable	4qogA-3k4xA: 14.67 4qogB-3k4xA: 14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QOG_A_ML1A302_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	4 / 8	ILE A 427 PHE A 504 PHE A 506 ILE A 449	None	0.87A	4qogA-3k4xA: undetectable 4qogB-3k4xA: undetectable	4qogA-3k4xA: 14.67 4qogB-3k4xA: 14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QOG_A_ML1A302_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	4 / 8	ILE A 694 PHE A 771 PHE A 773 ILE A 716	None	0.81A	4qogA-3k4xA: undetectable 4qogB-3k4xA: undetectable	4qogA-3k4xA: 14.67 4qogB-3k4xA: 14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4W5Q_A_IPHA902_0 (PROTEIN ARGONAUTE-2)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	4 / 6	ARG A 644 ILE A 645 ILE A 414 ASP A 417	None	1.09A	4w5qA-3k4xA: undetectable	4w5qA-3k4xA: 22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z4C_A_IPHA903_0 (PROTEIN ARGONAUTE-2)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	4 / 6	ARG A 377 ILE A 378 ILE A 147 ASP A 150	None	1.21A	4z4cA-3k4xA: undetectable	4z4cA-3k4xA: 22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B1B_C_CHDC306_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	4 / 6	ARG A 491 GLN A 505 PHE A 504 LEU A 406	None	1.06A	5b1bC-3k4xA: undetectable 5b1bJ-3k4xA: undetectable	5b1bC-3k4xA: 14.85 5b1bJ-3k4xA: 5.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EAJ_A_FOLA201_0 (DIHYDROFOLATE REDUCTASE)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	6 / 12	ALA A 476 LEU A 517 PHE A 474 ILE A 494 LEU A 496 ILE A 427	None	1.43A	5eajA-3k4xA: undetectable	5eajA-3k4xA: 12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FHR_B_SAMB303_1 (CATECHOL O-METHYLTRANSFERASE)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	4 / 5	SER A 756 SER A 583 GLN A 572 ASP A 774	None	1.35A	5fhrB-3k4xA: undetectable	5fhrB-3k4xA: 15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5GWK_F_EVPF102_1 (DNA TOPOISOMERASE 2-ALPHA)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	4 / 5	GLY A 18 ASP A 17 MET A 70 MET A 119	None	1.24A	5gwkA-3k4xA: undetectable	5gwkA-3k4xA: 22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5GWK_F_EVPF102_1 (DNA TOPOISOMERASE 2-ALPHA)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	4 / 5	GLY A 552 ASP A 551 MET A 604 MET A 653	None	1.24A	5gwkA-3k4xA: undetectable	5gwkA-3k4xA: 22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UJX_A_FOLA201_0 (DIHYDROFOLATE REDUCTASE)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	6 / 12	ALA A 476 LEU A 517 PHE A 474 ILE A 494 LEU A 496 ILE A 427	None	1.45A	5ujxA-3k4xA: undetectable	5ujxA-3k4xA: 12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XXI_A_LSNA503_1 (CYTOCHROME P450 2C9)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	5 / 12	ILE A 395 LEU A 313 LEU A 496 PRO A 501 LEU A 398	None	1.26A	5xxiA-3k4xA: undetectable	5xxiA-3k4xA: 20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z6J_A_FOLA201_0 (DIHYDROFOLATE REDUCTASE)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	6 / 12	ALA A 476 LEU A 517 PHE A 474 ILE A 494 LEU A 496 ILE A 427	None	1.44A	5z6jA-3k4xA: undetectable	5z6jA-3k4xA: 12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DH0_A_017A101_2 (PROTEASE)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	3 / 3	LEU A 784 ASP A 668 ILE A 696	None	0.64A	6dh0B-3k4xA: undetectable	6dh0B-3k4xA: 7.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NMF_C_CHDC305_0 (CYTOCHROME C OXIDASE SUBUNIT 3)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	4 / 4	ARG A 224 GLN A 238 PHE A 237 LEU A 139	None	1.21A	6nmfC-3k4xA: 0.0	6nmfC-3k4xA: 14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NMF_C_CHDC305_0 (CYTOCHROME C OXIDASE SUBUNIT 3)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	4 / 4	ARG A 491 GLN A 505 PHE A 504 LEU A 406	None	1.20A	6nmfC-3k4xA: 0.0	6nmfC-3k4xA: 14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NMF_C_CHDC305_0 (CYTOCHROME C OXIDASE SUBUNIT 3)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	4 / 4	ARG A 758 GLN A 772 PHE A 771 LEU A 673	None	1.21A	6nmfC-3k4xA: 0.0	6nmfC-3k4xA: 14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NMP_C_CHDC307_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3k4x	PROLIFERATING CELL NUCLEAR ANTIGEN (Saccharomyces cerevisiae)	4 / 6	GLN A 296 PHE A 295 LEU A 513 PHE A 515	None	1.21A	6nmpC-3k4xA: undetectable 6nmpJ-3k4xA: undetectable	6nmpC-3k4xA: 14.85 6nmpJ-3k4xA: 5.90

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1RA2_A_FOLA161_0","DIHYDROFOLATE REDUCTASE","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",6,"ALA A 476;LEU A 517;PHE A 474;ILE A 494;LEU A 496;ILE A 427","None","1.40A","1ra2A-3k4xA:undetectable","1ra2A-3k4xA:12.29"],["1RA2_A_FOLA161_0","DIHYDROFOLATE REDUCTASE","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",6,"ALA A 743;LEU A 784;PHE A 741;ILE A 761;LEU A 763;ILE A 694","None","1.40A","1ra2A-3k4xA:undetectable","1ra2A-3k4xA:12.29"],["1RA8_A_FOLA161_0","DIHYDROFOLATE REDUCTASE","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",6,"ALA A 476;LEU A 517;PHE A 474;ILE A 494;LEU A 496;ILE A 427","None","1.38A","1ra8A-3k4xA:undetectable","1ra8A-3k4xA:12.29"],["1RA8_A_FOLA161_0","DIHYDROFOLATE REDUCTASE","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",6,"ALA A 743;LEU A 784;PHE A 741;ILE A 761;LEU A 763;ILE A 694","None","1.38A","1ra8A-3k4xA:undetectable","1ra8A-3k4xA:12.29"],["1RB2_A_FOLA161_0","DIHYDROFOLATE REDUCTASE","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",6,"ALA A 743;LEU A 784;PHE A 741;ILE A 761;LEU A 763;ILE A 694","None","1.41A","1rb2A-3k4xA:undetectable","1rb2A-3k4xA:12.29"],["1WRL_B_TFPB203_1","TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",4,"VAL A  23;LEU A  72;PHE A 248;SER A 220","None","0.92A","1wrlB-3k4xA:undetectable","1wrlB-3k4xA:7.98"],["1Z11_C_8MOC501_0","CYTOCHROME P450, FAMILY 2, SUBFAMILY A, POLYPEPTIDE 6","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",5,"ASN A 159;ILE A 158;ILE A 227;LEU A 229;PHE A 237","None","1.13A","1z11C-3k4xA:undetectable","1z11C-3k4xA:20.47"],["1Z11_C_8MOC501_0","CYTOCHROME P450, FAMILY 2, SUBFAMILY A, POLYPEPTIDE 6","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",5,"ASN A 426;ILE A 425;ILE A 494;LEU A 496;PHE A 504","None","1.13A","1z11C-3k4xA:undetectable","1z11C-3k4xA:20.47"],["2CL5_B_SAMB1217_1","CATECHOL O-METHYLTRANSFERASE","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",4,"SER A 756;SER A 583;GLN A 572;ASP A 774","None","1.33A","2cl5B-3k4xA:undetectable","2cl5B-3k4xA:14.96"],["2D0K_B_FOLB2161_0","DIHYDROFOLATE REDUCTASE","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",6,"ALA A 209;LEU A 250;PHE A 207;ILE A 227;LEU A 229;ILE A 160","None","1.44A","2d0kB-3k4xA:undetectable","2d0kB-3k4xA:12.04"],["2D0K_B_FOLB2161_0","DIHYDROFOLATE REDUCTASE","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",6,"ALA A 476;LEU A 517;PHE A 474;ILE A 494;LEU A 496;ILE A 427","None","1.37A","2d0kB-3k4xA:undetectable","2d0kB-3k4xA:12.04"],["2D0K_B_FOLB2161_0","DIHYDROFOLATE REDUCTASE","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",6,"ALA A 743;LEU A 784;PHE A 741;ILE A 761;LEU A 763;ILE A 694","None","1.37A","2d0kB-3k4xA:undetectable","2d0kB-3k4xA:12.04"],["2LBD_A_REAA500_1","RETINOIC ACID RECEPTOR GAMMA","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",5,"PHE A 273;LYS A 509;ILE A 302;PHE A 324;LEU A 346","None","1.24A","2lbdA-3k4xA:undetectable","2lbdA-3k4xA:16.54"],["2QWX_A_ML1A233_1","RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE];RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE]","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",4,"ILE A 160;PHE A 237;PHE A 239;ILE A 182","None","0.89A","2qwxA-3k4xA:undetectable;2qwxB-3k4xA:undetectable","2qwxA-3k4xA:14.67;2qwxB-3k4xA:14.67"],["2ZVJ_A_SAMA301_1","CATECHOL O-METHYLTRANSFERASE","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",4,"SER A 756;SER A 583;GLN A 572;ASP A 774","None","1.36A","2zvjA-3k4xA:undetectable","2zvjA-3k4xA:15.10"],["3ABK_C_CHDC271_0","CYTOCHROME C OXIDASE SUBUNIT 3","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",4,"ARG A 224;GLN A 238;PHE A 237;LEU A 139","None","1.20A","3abkC-3k4xA:0.0","3abkC-3k4xA:14.85"],["3ABK_C_CHDC271_0","CYTOCHROME C OXIDASE SUBUNIT 3","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",4,"ARG A 491;GLN A 505;PHE A 504;LEU A 406","None","1.16A","3abkC-3k4xA:0.0","3abkC-3k4xA:14.85"],["3ABK_C_CHDC271_0","CYTOCHROME C OXIDASE SUBUNIT 3","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",4,"ARG A 758;GLN A 772;PHE A 771;LEU A 673","None","1.20A","3abkC-3k4xA:0.0","3abkC-3k4xA:14.85"],["3ABL_C_CHDC271_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 3","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",4,"ARG A 491;GLN A 505;PHE A 504;LEU A 406","None","1.14A","3ablC-3k4xA:undetectable;3ablJ-3k4xA:undetectable","3ablC-3k4xA:14.85;3ablJ-3k4xA:5.90"],["3ABL_P_CHDP1271_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 3","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",4,"ARG A 491;GLN A 505;PHE A 504;LEU A 406","None","1.15A","3ablP-3k4xA:undetectable;3ablW-3k4xA:undetectable","3ablP-3k4xA:14.85;3ablW-3k4xA:5.90"],["3CJT_C_SAMC302_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",6,"LEU A  50;VAL A  40;LEU A  47;ILE A  16;LEU A 246;LEU A 221","None","1.48A","3cjtC-3k4xA:undetectable","3cjtC-3k4xA:15.80"],["3CJT_C_SAMC302_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",6,"LEU A 584;VAL A 574;LEU A 581;ILE A 550;LEU A 780;LEU A 755","None","1.44A","3cjtC-3k4xA:undetectable","3cjtC-3k4xA:15.80"],["3CJT_K_SAMK302_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",5,"LEU A 584;VAL A 574;LEU A 581;LEU A 780;LEU A 755","None","1.43A","3cjtK-3k4xA:undetectable","3cjtK-3k4xA:15.80"],["3CJT_O_SAMO302_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",6,"LEU A 584;VAL A 574;LEU A 581;ILE A 550;LEU A 780;LEU A 755","None","1.46A","3cjtO-3k4xA:undetectable","3cjtO-3k4xA:15.80"],["3OWX_A_XRAA233_2","RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE];RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE]","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",4,"VAL A  26;PHE A  12;ILE A  15;PHE A   6","None","1.09A","3owxB-3k4xA:undetectable","3owxB-3k4xA:14.67"],["3OWX_A_XRAA233_2","RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE];RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE]","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",4,"VAL A 293;PHE A 279;ILE A 282;PHE A 273","None","0.99A","3owxB-3k4xA:undetectable","3owxB-3k4xA:14.67"],["3R55_A_PZAA598_0","LACTOPEROXIDASE","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",3,"GLU A 318;PHE A 512;GLN A 305","None","0.73A","3r55A-3k4xA:undetectable","3r55A-3k4xA:21.86"],["3UVV_A_T3A501_1","THYROID HORMONE RECEPTOR ALPHA","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",5,"ILE A  15;ILE A  16;LEU A  90;LEU A 101;ILE A  99","None","1.06A","3uvvA-3k4xA:undetectable","3uvvA-3k4xA:15.44"],["3UVV_A_T3A501_1","THYROID HORMONE RECEPTOR ALPHA","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",5,"ILE A 282;ILE A 283;LEU A 357;LEU A 368;ILE A 366","None","1.08A","3uvvA-3k4xA:undetectable","3uvvA-3k4xA:15.44"],["3W67_C_VIVC301_0","ALPHA-TOCOPHEROL TRANSFER PROTEIN","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",5,"ILE A  99;ALA A  37;PHE A  28;ILE A  16;VAL A  48","None","1.15A","3w67C-3k4xA:undetectable","3w67C-3k4xA:16.12"],["4D9H_A_ADNA301_1","PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",5,"SER A 382;GLY A 178;SER A 177;ASP A 172;VAL A 170","None","1.31A","4d9hA-3k4xA:undetectable","4d9hA-3k4xA:16.43"],["4DA6_A_GA2A301_1","PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",5,"SER A 382;GLY A 178;SER A 177;ASP A 172;VAL A 170","None","1.33A","4da6A-3k4xA:undetectable","4da6A-3k4xA:16.43"],["4DAN_B_2FAB301_1","PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE;PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",5,"SER A 382;GLY A 178;SER A 177;ASP A 172;VAL A 170","None","1.25A","4danA-3k4xA:undetectable;4danB-3k4xA:undetectable","4danA-3k4xA:16.43;4danB-3k4xA:16.43"],["4EJJ_D_NCTD501_1","CYTOCHROME P450 2A6","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",4,"PHE A  57;GLY A 244;ILE A  15;LEU A  11","None","0.67A","4ejjD-3k4xA:undetectable","4ejjD-3k4xA:20.47"],["4EJJ_D_NCTD501_1","CYTOCHROME P450 2A6","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",4,"PHE A 324;GLY A 511;ILE A 282;LEU A 278","None","0.72A","4ejjD-3k4xA:undetectable","4ejjD-3k4xA:20.47"],["4EJJ_D_NCTD501_1","CYTOCHROME P450 2A6","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",4,"PHE A 591;GLY A 778;ILE A 549;LEU A 545","None","0.73A","4ejjD-3k4xA:undetectable","4ejjD-3k4xA:20.47"],["4FHB_A_FOLA201_0","DIHYDROFOLATE REDUCTASE","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",6,"ALA A 476;LEU A 517;PHE A 474;ILE A 494;LEU A 496;ILE A 427","None","1.45A","4fhbA-3k4xA:undetectable","4fhbA-3k4xA:12.29"],["4I13_A_FOLA201_0","DIHYDROFOLATE REDUCTASE","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",6,"ALA A 743;LEU A 784;PHE A 741;ILE A 761;LEU A 763;ILE A 694","None","1.42A","4i13A-3k4xA:undetectable","4i13A-3k4xA:12.29"],["4I1N_A_FOLA201_0","DIHYDROFOLATE REDUCTASE","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",5,"ALA A 271;LEU A 355;PHE A 279;LYS A 280;LEU A 342","None","1.36A","4i1nA-3k4xA:undetectable","4i1nA-3k4xA:12.29"],["4J7X_B_SASB804_1","SEPIAPTERIN REDUCTASE","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",5,"LEU A 536;PRO A 630;MET A 604;GLY A 603;LEU A 652","None","1.14A","4j7xB-3k4xA:undetectable","4j7xB-3k4xA:16.88"],["4K38_B_SAMB504_0","ANAEROBIC SULFATASE-MATURATING ENZYME","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",5,"PHE A 741;GLU A 677;LEU A 731;ILE A 696;LEU A 739","None","1.47A","4k38B-3k4xA:undetectable","4k38B-3k4xA:17.48"],["4K39_A_SAMA504_0","ANAEROBIC SULFATASE-MATURATING ENZYME","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",5,"PHE A 741;GLU A 677;LEU A 731;ILE A 696;LEU A 739","None","1.33A","4k39A-3k4xA:undetectable","4k39A-3k4xA:17.48"],["4NX6_A_FOLA201_0","DIHYDROFOLATE REDUCTASE","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",6,"ALA A 476;LEU A 517;PHE A 474;ILE A 494;LEU A 496;ILE A 427","None","1.42A","4nx6A-3k4xA:undetectable","4nx6A-3k4xA:12.29"],["4NX6_A_FOLA201_0","DIHYDROFOLATE REDUCTASE","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",6,"ALA A 743;LEU A 784;PHE A 741;ILE A 761;LEU A 763;ILE A 694","None","1.43A","4nx6A-3k4xA:undetectable","4nx6A-3k4xA:12.29"],["4NX7_A_FOLA202_0","DIHYDROFOLATE REDUCTASE","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",6,"ALA A 476;LEU A 517;PHE A 474;ILE A 494;LEU A 496;ILE A 427","None","1.43A","4nx7A-3k4xA:undetectable","4nx7A-3k4xA:12.29"],["4NX7_A_FOLA202_0","DIHYDROFOLATE REDUCTASE","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",6,"ALA A 743;LEU A 784;PHE A 741;ILE A 761;LEU A 763;ILE A 694","None","1.44A","4nx7A-3k4xA:undetectable","4nx7A-3k4xA:12.29"],["4P3R_A_FOLA201_0","DIHYDROFOLATE REDUCTASE","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",6,"ALA A 476;LEU A 517;PHE A 474;ILE A 494;LEU A 496;ILE A 427","None","1.42A","4p3rA-3k4xA:undetectable","4p3rA-3k4xA:12.29"],["4P3R_A_FOLA201_0","DIHYDROFOLATE REDUCTASE","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",6,"ALA A 743;LEU A 784;PHE A 741;ILE A 761;LEU A 763;ILE A 694","None","1.43A","4p3rA-3k4xA:undetectable","4p3rA-3k4xA:12.29"],["4PST_A_FOLA201_0","DIHYDROFOLATE REDUCTASE","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",6,"ALA A 476;LEU A 517;PHE A 474;ILE A 494;LEU A 496;ILE A 427","None","1.45A","4pstA-3k4xA:undetectable","4pstA-3k4xA:12.29"],["4QOG_A_ML1A302_1","RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE];RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE]","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",4,"ILE A 160;PHE A 237;PHE A 239;ILE A 182","None","0.82A","4qogA-3k4xA:undetectable;4qogB-3k4xA:undetectable","4qogA-3k4xA:14.67;4qogB-3k4xA:14.67"],["4QOG_A_ML1A302_1","RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE];RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE]","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",4,"ILE A 427;PHE A 504;PHE A 506;ILE A 449","None","0.87A","4qogA-3k4xA:undetectable;4qogB-3k4xA:undetectable","4qogA-3k4xA:14.67;4qogB-3k4xA:14.67"],["4QOG_A_ML1A302_1","RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE];RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE]","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",4,"ILE A 694;PHE A 771;PHE A 773;ILE A 716","None","0.81A","4qogA-3k4xA:undetectable;4qogB-3k4xA:undetectable","4qogA-3k4xA:14.67;4qogB-3k4xA:14.67"],["4W5Q_A_IPHA902_0","PROTEIN ARGONAUTE-2","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",4,"ARG A 644;ILE A 645;ILE A 414;ASP A 417","None","1.09A","4w5qA-3k4xA:undetectable","4w5qA-3k4xA:22.62"],["4Z4C_A_IPHA903_0","PROTEIN ARGONAUTE-2","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",4,"ARG A 377;ILE A 378;ILE A 147;ASP A 150","None","1.21A","4z4cA-3k4xA:undetectable","4z4cA-3k4xA:22.62"],["5B1B_C_CHDC306_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",4,"ARG A 491;GLN A 505;PHE A 504;LEU A 406","None","1.06A","5b1bC-3k4xA:undetectable;5b1bJ-3k4xA:undetectable","5b1bC-3k4xA:14.85;5b1bJ-3k4xA:5.90"],["5EAJ_A_FOLA201_0","DIHYDROFOLATE REDUCTASE","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",6,"ALA A 476;LEU A 517;PHE A 474;ILE A 494;LEU A 496;ILE A 427","None","1.43A","5eajA-3k4xA:undetectable","5eajA-3k4xA:12.29"],["5FHR_B_SAMB303_1","CATECHOL O-METHYLTRANSFERASE","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",4,"SER A 756;SER A 583;GLN A 572;ASP A 774","None","1.35A","5fhrB-3k4xA:undetectable","5fhrB-3k4xA:15.57"],["5GWK_F_EVPF102_1","DNA TOPOISOMERASE 2-ALPHA","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",4,"GLY A  18;ASP A  17;MET A  70;MET A 119","None","1.24A","5gwkA-3k4xA:undetectable","5gwkA-3k4xA:22.98"],["5GWK_F_EVPF102_1","DNA TOPOISOMERASE 2-ALPHA","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",4,"GLY A 552;ASP A 551;MET A 604;MET A 653","None","1.24A","5gwkA-3k4xA:undetectable","5gwkA-3k4xA:22.98"],["5UJX_A_FOLA201_0","DIHYDROFOLATE REDUCTASE","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",6,"ALA A 476;LEU A 517;PHE A 474;ILE A 494;LEU A 496;ILE A 427","None","1.45A","5ujxA-3k4xA:undetectable","5ujxA-3k4xA:12.29"],["5XXI_A_LSNA503_1","CYTOCHROME P450 2C9","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",5,"ILE A 395;LEU A 313;LEU A 496;PRO A 501;LEU A 398","None","1.26A","5xxiA-3k4xA:undetectable","5xxiA-3k4xA:20.58"],["5Z6J_A_FOLA201_0","DIHYDROFOLATE REDUCTASE","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",6,"ALA A 476;LEU A 517;PHE A 474;ILE A 494;LEU A 496;ILE A 427","None","1.44A","5z6jA-3k4xA:undetectable","5z6jA-3k4xA:12.50"],["6DH0_A_017A101_2","PROTEASE","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",3,"LEU A 784;ASP A 668;ILE A 696","None","0.64A","6dh0B-3k4xA:undetectable","6dh0B-3k4xA:7.20"],["6NMF_C_CHDC305_0","CYTOCHROME C OXIDASE SUBUNIT 3","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",4,"ARG A 224;GLN A 238;PHE A 237;LEU A 139","None","1.21A","6nmfC-3k4xA:0.0","6nmfC-3k4xA:14.85"],["6NMF_C_CHDC305_0","CYTOCHROME C OXIDASE SUBUNIT 3","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",4,"ARG A 491;GLN A 505;PHE A 504;LEU A 406","None","1.20A","6nmfC-3k4xA:0.0","6nmfC-3k4xA:14.85"],["6NMF_C_CHDC305_0","CYTOCHROME C OXIDASE SUBUNIT 3","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",4,"ARG A 758;GLN A 772;PHE A 771;LEU A 673","None","1.21A","6nmfC-3k4xA:0.0","6nmfC-3k4xA:14.85"],["6NMP_C_CHDC307_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3k4x","PROLIFERATING CELL NUCLEAR ANTIGEN","Saccharomyces cerevisiae",4,"GLN A 296;PHE A 295;LEU A 513;PHE A 515","None","1.21A","6nmpC-3k4xA:undetectable;6nmpJ-3k4xA:undetectable","6nmpC-3k4xA:14.85;6nmpJ-3k4xA:5.90"]]