SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3k5h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 9 THR A 358
GLY A 282
ALA A 221
HIS A 277
ILE A 307
 None
 1.26A 1c9sA-3k5hA:
undetectable
1c9sB-3k5hA:
undetectable		 1c9sA-3k5hA:
11.53
1c9sB-3k5hA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 9 GLY A 282
ALA A 221
HIS A 277
ILE A 307
THR A 358
 None
 1.25A 1c9sL-3k5hA:
undetectable
1c9sM-3k5hA:
undetectable		 1c9sL-3k5hA:
11.53
1c9sM-3k5hA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 9 GLY A 282
ALA A 221
HIS A 277
ILE A 307
THR A 358
 None
 1.26A 1c9sO-3k5hA:
undetectable
1c9sP-3k5hA:
undetectable		 1c9sO-3k5hA:
11.53
1c9sP-3k5hA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 9 GLY A 282
ALA A 221
HIS A 277
ILE A 307
THR A 358
 None
 1.26A 1c9sS-3k5hA:
undetectable
1c9sT-3k5hA:
undetectable		 1c9sS-3k5hA:
11.53
1c9sT-3k5hA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4003_1
(SERUM ALBUMIN)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		4 / 6 VAL A 135
GLY A 136
ALA A 180
LEU A 124
 None
 0.59A 1e7bB-3k5hA:
undetectable		 1e7bB-3k5hA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 9 GLY A 282
ALA A 221
HIS A 277
ILE A 307
THR A 358
 None
 1.28A 1gtfO-3k5hA:
undetectable
1gtfP-3k5hA:
undetectable		 1gtfO-3k5hA:
11.53
1gtfP-3k5hA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 10 GLY A 282
ALA A 221
HIS A 277
ILE A 307
THR A 358
 None
 1.29A 1gtfP-3k5hA:
undetectable
1gtfQ-3k5hA:
undetectable		 1gtfP-3k5hA:
11.53
1gtfQ-3k5hA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 10 THR A 358
GLY A 282
ALA A 221
HIS A 277
ILE A 307
 None
 1.28A 1gtfL-3k5hA:
undetectable
1gtfV-3k5hA:
undetectable		 1gtfL-3k5hA:
11.53
1gtfV-3k5hA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 10 GLY A 282
ALA A 221
HIS A 277
ILE A 307
THR A 358
 None
 1.33A 1gtnN-3k5hA:
undetectable
1gtnO-3k5hA:
undetectable		 1gtnN-3k5hA:
11.53
1gtnO-3k5hA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 9 GLY A 282
ALA A 221
HIS A 277
ILE A 307
THR A 358
 None
 1.22A 1gtnR-3k5hA:
undetectable
1gtnS-3k5hA:
undetectable		 1gtnR-3k5hA:
11.53
1gtnS-3k5hA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HVY_A_D16A414_1
(THYMIDYLATE SYNTHASE)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 12 PHE A 251
GLU A  75
ILE A 101
ASN A 103
LEU A 111
 None
MG  A 402 ( 3.8A)
None
None
None
 1.25A 1hvyA-3k5hA:
undetectable		 1hvyA-3k5hA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HVY_C_D16C416_1
(THYMIDYLATE SYNTHASE)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 11 PHE A 251
GLU A  75
ILE A 101
ASN A 103
LEU A 111
 None
MG  A 402 ( 3.8A)
None
None
None
 1.24A 1hvyC-3k5hA:
undetectable		 1hvyC-3k5hA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KI7_B_ID2B2_0
(THYMIDINE KINASE)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 12 GLU A 208
ILE A 312
ILE A 371
ARG A 224
GLU A 368
 None
 1.41A 1ki7B-3k5hA:
undetectable		 1ki7B-3k5hA:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA140_0
(LYSOZYME C)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		3 / 3 ASN A 225
ALA A 223
ASN A 231
 None
 0.64A 1n4fA-3k5hA:
undetectable		 1n4fA-3k5hA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_Q_TRPQ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 10 GLY A 282
ALA A 221
HIS A 277
ILE A 307
THR A 358
 None
 1.31A 1utdQ-3k5hA:
undetectable
1utdR-3k5hA:
undetectable		 1utdQ-3k5hA:
11.53
1utdR-3k5hA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 10 GLY A 282
ALA A 221
HIS A 277
ILE A 307
THR A 358
 None
 1.29A 1utdR-3k5hA:
undetectable
1utdS-3k5hA:
undetectable		 1utdR-3k5hA:
11.53
1utdS-3k5hA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A8T_B_ADNB252_1
(U8 SNORNA-BINDING
PROTEIN X29)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		4 / 8 GLY A  12
ASN A  37
SER A  38
GLN A  42
 None
 1.04A 2a8tB-3k5hA:
undetectable		 2a8tB-3k5hA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A8T_B_ADNB252_1
(U8 SNORNA-BINDING
PROTEIN X29)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		4 / 8 GLY A  13
ASN A  37
SER A  38
GLN A  42
 None
 0.88A 2a8tB-3k5hA:
undetectable		 2a8tB-3k5hA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNP_A_ROCA401_2
(PROTEASE)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 11 ALA A  23
VAL A   7
ILE A 295
VAL A  32
VAL A  30
 None
 0.95A 2nnpB-3k5hA:
undetectable		 2nnpB-3k5hA:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAT_A_CLMA301_0
(XENOBIOTIC
ACETYLTRANSFERASE)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		3 / 3 GLY A 276
TYR A 278
SER A 275
 None
 0.78A 2xatA-3k5hA:
undetectable		 2xatA-3k5hA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H9U_A_ADNA439_1
(ADENOSYLHOMOCYSTEINA
SE)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 10 HIS A 273
THR A 209
GLY A 276
HIS A 277
MET A 313
 None
 1.40A 3h9uA-3k5hA:
3.3		 3h9uA-3k5hA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H9U_B_ADNB438_1
(ADENOSYLHOMOCYSTEINA
SE)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 10 HIS A 273
THR A 209
GLY A 276
HIS A 277
MET A 313
 None
 1.43A 3h9uB-3k5hA:
3.5		 3h9uB-3k5hA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H9U_C_ADNC438_1
(ADENOSYLHOMOCYSTEINA
SE)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 10 HIS A 273
THR A 209
GLY A 276
HIS A 277
MET A 313
 None
 1.40A 3h9uC-3k5hA:
2.2		 3h9uC-3k5hA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H9U_D_ADND438_1
(ADENOSYLHOMOCYSTEINA
SE)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 10 HIS A 273
THR A 209
GLY A 276
HIS A 277
MET A 313
 None
 1.41A 3h9uD-3k5hA:
3.5		 3h9uD-3k5hA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 12 ILE A 101
VAL A  69
ILE A 272
LEU A  19
VAL A   7
 None
 1.14A 3w68B-3k5hA:
undetectable		 3w68B-3k5hA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_0
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 12 THR A 279
ILE A 193
GLN A 287
ILE A 300
ALA A 294
 None
 1.25A 4rp8C-3k5hA:
undetectable		 4rp8C-3k5hA:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_A_AZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 11 HIS A 291
VAL A  69
VAL A   7
LEU A 296
ALA A 294
 None
 1.42A 4ygfA-3k5hA:
undetectable		 4ygfA-3k5hA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_C_AZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 11 HIS A 291
VAL A  69
VAL A   7
LEU A 296
ALA A 294
 None
 1.44A 4ygfC-3k5hA:
undetectable		 4ygfC-3k5hA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_A_MZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 12 HIS A 291
VAL A  69
VAL A   7
LEU A 296
ALA A 294
 None
 1.32A 4yhaA-3k5hA:
undetectable		 4yhaA-3k5hA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_G_MZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 12 HIS A 291
VAL A  69
VAL A   7
LEU A 296
ALA A 294
 None
 1.32A 4yhaG-3k5hA:
undetectable		 4yhaG-3k5hA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 10 GLY A 282
ALA A 221
HIS A 277
ILE A 307
THR A 358
 None
 1.27A 5eeuR-3k5hA:
undetectable
5eeuS-3k5hA:
undetectable		 5eeuR-3k5hA:
11.53
5eeuS-3k5hA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 10 GLY A 282
ALA A 221
HIS A 277
ILE A 307
THR A 358
 None
 1.28A 5eeuS-3k5hA:
undetectable
5eeuT-3k5hA:
undetectable		 5eeuS-3k5hA:
11.53
5eeuT-3k5hA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 10 GLY A 282
ALA A 221
HIS A 277
ILE A 307
THR A 358
 None
 1.27A 5eevR-3k5hA:
undetectable
5eevS-3k5hA:
undetectable		 5eevR-3k5hA:
11.53
5eevS-3k5hA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 10 GLY A 282
ALA A 221
HIS A 277
ILE A 307
THR A 358
 None
 1.29A 5eevS-3k5hA:
undetectable
5eevT-3k5hA:
undetectable		 5eevS-3k5hA:
11.53
5eevT-3k5hA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 10 GLY A 282
ALA A 221
HIS A 277
ILE A 307
THR A 358
 None
 1.27A 5eewR-3k5hA:
undetectable
5eewS-3k5hA:
undetectable		 5eewR-3k5hA:
11.53
5eewS-3k5hA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 10 GLY A 282
ALA A 221
HIS A 277
ILE A 307
THR A 358
 None
 1.29A 5eewS-3k5hA:
undetectable
5eewT-3k5hA:
undetectable		 5eewS-3k5hA:
11.53
5eewT-3k5hA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 10 GLY A 282
ALA A 221
HIS A 277
ILE A 307
THR A 358
 None
 1.28A 5eexR-3k5hA:
undetectable
5eexS-3k5hA:
undetectable		 5eexR-3k5hA:
11.53
5eexS-3k5hA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 10 GLY A 282
ALA A 221
HIS A 277
ILE A 307
THR A 358
 None
 1.29A 5eexS-3k5hA:
undetectable
5eexT-3k5hA:
undetectable		 5eexS-3k5hA:
11.53
5eexT-3k5hA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 10 GLY A 282
ALA A 221
HIS A 277
ILE A 307
THR A 358
 None
 1.28A 5eeyR-3k5hA:
undetectable
5eeyS-3k5hA:
undetectable		 5eeyR-3k5hA:
11.53
5eeyS-3k5hA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 10 GLY A 282
ALA A 221
HIS A 277
ILE A 307
THR A 358
 None
 1.29A 5eeyS-3k5hA:
undetectable
5eeyT-3k5hA:
undetectable		 5eeyS-3k5hA:
11.53
5eeyT-3k5hA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 10 GLY A 282
ALA A 221
HIS A 277
ILE A 307
THR A 358
 None
 1.28A 5eezR-3k5hA:
undetectable
5eezS-3k5hA:
undetectable		 5eezR-3k5hA:
11.53
5eezS-3k5hA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 10 GLY A 282
ALA A 221
HIS A 277
ILE A 307
THR A 358
 None
 1.30A 5eezS-3k5hA:
undetectable
5eezT-3k5hA:
undetectable		 5eezS-3k5hA:
11.53
5eezT-3k5hA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 10 GLY A 282
ALA A 221
HIS A 277
ILE A 307
THR A 358
 None
 1.28A 5ef0R-3k5hA:
undetectable
5ef0S-3k5hA:
undetectable		 5ef0R-3k5hA:
11.53
5ef0S-3k5hA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 10 GLY A 282
ALA A 221
HIS A 277
ILE A 307
THR A 358
 None
 1.30A 5ef0S-3k5hA:
undetectable
5ef0T-3k5hA:
undetectable		 5ef0S-3k5hA:
11.53
5ef0T-3k5hA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 10 GLY A 282
ALA A 221
HIS A 277
ILE A 307
THR A 358
 None
 1.28A 5ef1R-3k5hA:
undetectable
5ef1S-3k5hA:
undetectable		 5ef1R-3k5hA:
11.53
5ef1S-3k5hA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 10 GLY A 282
ALA A 221
HIS A 277
ILE A 307
THR A 358
 None
 1.30A 5ef1S-3k5hA:
undetectable
5ef1T-3k5hA:
undetectable		 5ef1S-3k5hA:
11.53
5ef1T-3k5hA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 10 GLY A 282
ALA A 221
HIS A 277
ILE A 307
THR A 358
 None
 1.28A 5ef2R-3k5hA:
undetectable
5ef2S-3k5hA:
undetectable		 5ef2R-3k5hA:
11.53
5ef2S-3k5hA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 10 GLY A 282
ALA A 221
HIS A 277
ILE A 307
THR A 358
 None
 1.30A 5ef2S-3k5hA:
undetectable
5ef2T-3k5hA:
undetectable		 5ef2S-3k5hA:
11.53
5ef2T-3k5hA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 10 GLY A 282
ALA A 221
HIS A 277
ILE A 307
THR A 358
 None
 1.28A 5ef3R-3k5hA:
undetectable
5ef3S-3k5hA:
undetectable		 5ef3R-3k5hA:
11.53
5ef3S-3k5hA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 10 GLY A 282
ALA A 221
HIS A 277
ILE A 307
THR A 358
 None
 1.30A 5ef3S-3k5hA:
undetectable
5ef3T-3k5hA:
undetectable		 5ef3S-3k5hA:
11.53
5ef3T-3k5hA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND3_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 12 LEU A 170
LEU A 145
ALA A 180
THR A 128
ARG A 122
 None
 1.22A 5nd3B-3k5hA:
undetectable		 5nd3B-3k5hA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_G_EZLG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 9 HIS A 291
VAL A  69
VAL A   7
LEU A 296
ALA A 294
 None
 1.42A 5tt3G-3k5hA:
undetectable		 5tt3G-3k5hA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9M_A_NIOA401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		4 / 8 VAL A 201
VAL A 194
LYS A 196
PHE A 251
 None
 0.74A 5y9mA-3k5hA:
undetectable		 5y9mA-3k5hA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF9_B_NIOB401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		4 / 7 VAL A 201
VAL A 194
LYS A 196
PHE A 251
 None
 0.73A 5yf9B-3k5hA:
undetectable		 5yf9B-3k5hA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D9K_F_ACTF802_0
(UNCHARACTERIZED
PROTEIN)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		3 / 3 TYR A 141
ALA A 180
LEU A 132
 None
 0.52A 6d9kF-3k5hA:
3.2		 6d9kF-3k5hA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA502_0
(ADENOSYLHOMOCYSTEINA
SE)		 3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE
(Aspergillus
clavatus) 		5 / 12 HIS A 273
THR A 209
GLY A 276
HIS A 277
MET A 313
 None
 1.46A 6exiA-3k5hA:
undetectable		 6exiA-3k5hA:
13.97