SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3k5r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 3k5r CADHERIN 13
(Mus
musculus) 		3 / 3 ARG A 145
ASN A 103
THR A 139
 None
 0.73A 2q63A-3k5rA:
undetectable		 2q63A-3k5rA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM7_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3k5r CADHERIN 13
(Mus
musculus) 		4 / 7 ALA A 211
ILE A 113
ILE A 213
HIS A 115
 None
 1.04A 2zm7A-3k5rA:
undetectable		 2zm7A-3k5rA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGX_A_SALA102_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 3k5r CADHERIN 13
(Mus
musculus) 		4 / 7 VAL A 173
ILE A 148
TYR A 162
ILE A 170
 None
 1.03A 3hgxA-3k5rA:
undetectable		 3hgxA-3k5rA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3k5r CADHERIN 13
(Mus
musculus) 		4 / 8 ILE A   7
LEU A  93
VAL A  42
GLY A  41
 None
 0.84A 3w1wA-3k5rA:
undetectable		 3w1wA-3k5rA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WM2_A_ACTA605_0
(SALICYLATE-AMP
LIGASE)		 3k5r CADHERIN 13
(Mus
musculus) 		3 / 3 THR A  86
THR A  80
ARG A  36
 None
 1.07A 5wm2A-3k5rA:
undetectable		 5wm2A-3k5rA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWP_A_FVXA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 3k5r CADHERIN 13
(Mus
musculus) 		5 / 9 ASN A 159
ILE A 215
SER A 157
SER A 120
GLY A 119
 None
 1.18A 6awpA-3k5rA:
undetectable		 6awpA-3k5rA:
17.47