SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3k5s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DM6_A_IMNA1401_1 (NADP-DEPENDENT LEUKOTRIENE B4 12-HYDROXYDEHYDROGEN ASE)	3k5s	CADHERIN-13 (Gallus gallus)	5 / 10	TYR A 112 ALA A 209 ILE A 170 GLU A 190 ILE A 213	TYR A 112 ( 1.3A) ALA A 209 ( 0.0A) ILE A 170 ( 0.7A) GLU A 190 ( 0.5A) ILE A 213 ( 0.7A)	1.34A	2dm6A-3k5sA: undetectable 2dm6B-3k5sA: undetectable	2dm6A-3k5sA: 19.02 2dm6B-3k5sA: 19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YGQ_A_PCFA1275_0 (WNT INHIBITORY FACTOR 1)	3k5s	CADHERIN-13 (Gallus gallus)	5 / 12	LEU A 65 ILE A 95 LEU A 93 ILE A 9 ILE A 52	LEU A 65 ( 0.5A) ILE A 95 ( 0.6A) LEU A 93 ( 0.6A) ILE A 9 ( 0.7A) ILE A 52 ( 0.6A)	0.97A	2ygqA-3k5sA: undetectable	2ygqA-3k5sA: 18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AVP_A_MV2A313_1 (PANTOTHENATE KINASE)	3k5s	CADHERIN-13 (Gallus gallus)	4 / 7	VAL A 97 ASP A 102 TYR A 73 ILE A 49	VAL A 97 ( 0.6A) ASP A 102 ( 0.6A) TYR A 73 ( 1.3A) ILE A 49 ( 0.6A)	0.79A	3avpA-3k5sA: undetectable	3avpA-3k5sA: 20.33

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2DM6_A_IMNA1401_1","NADP-DEPENDENT LEUKOTRIENE B4 12-HYDROXYDEHYDROGENASE;NADP-DEPENDENT LEUKOTRIENE B4 12-HYDROXYDEHYDROGENASE","3k5s","CADHERIN-13","Gallus gallus",5,"TYR A 112;ALA A 209;ILE A 170;GLU A 190;ILE A 213","TYR A 112 ( 1.3A);ALA A 209 ( 0.0A);ILE A 170 ( 0.7A);GLU A 190 ( 0.5A);ILE A 213 ( 0.7A)","1.34A","2dm6A-3k5sA:undetectable;2dm6B-3k5sA:undetectable","2dm6A-3k5sA:19.02;2dm6B-3k5sA:19.02"],["2YGQ_A_PCFA1275_0","WNT INHIBITORY FACTOR 1","3k5s","CADHERIN-13","Gallus gallus",5,"LEU A  65;ILE A  95;LEU A  93;ILE A   9;ILE A  52","LEU A  65 ( 0.5A);ILE A  95 ( 0.6A);LEU A  93 ( 0.6A);ILE A   9 ( 0.7A);ILE A  52 ( 0.6A)","0.97A","2ygqA-3k5sA:undetectable","2ygqA-3k5sA:18.94"],["3AVP_A_MV2A313_1","PANTOTHENATE KINASE","3k5s","CADHERIN-13","Gallus gallus",4,"VAL A  97;ASP A 102;TYR A  73;ILE A  49","VAL A  97 ( 0.6A);ASP A 102 ( 0.6A);TYR A  73 ( 1.3A);ILE A  49 ( 0.6A)","0.79A","3avpA-3k5sA:undetectable","3avpA-3k5sA:20.33"]]