SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3k65'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CEA_A_ACAA90_1
(PLASMINOGEN)		 3k65 PROTHROMBIN
(Homo
sapiens) 		4 / 8 ASP A 223
ASP A 225
TRP A 230
TYR A 232
 None
 0.34A 1ceaA-3k65A:
undetectable
1ceaB-3k65A:
undetectable		 1ceaA-3k65A:
31.58
1ceaB-3k65A:
31.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CEA_B_ACAB90_1
(PLASMINOGEN)		 3k65 PROTHROMBIN
(Homo
sapiens) 		4 / 7 ASP A 223
ASP A 225
TRP A 230
TYR A 232
 None
 0.31A 1ceaB-3k65A:
undetectable		 1ceaB-3k65A:
31.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CEB_A_AMHA90_1
(PLASMINOGEN)		 3k65 PROTHROMBIN
(Homo
sapiens) 		4 / 7 ASP A 223
ASP A 225
TRP A 230
TYR A 232
 None
 0.38A 1cebA-3k65A:
11.0		 1cebA-3k65A:
31.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CEB_B_AMHB90_1
(PLASMINOGEN)		 3k65 PROTHROMBIN
(Homo
sapiens) 		4 / 7 ASP A 223
ASP A 225
TRP A 230
TYR A 232
 None
 0.40A 1cebB-3k65A:
11.0		 1cebB-3k65A:
31.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BVV_A_CPFA1081_1
(APOLIPOPROTEIN(A))		 3k65 PROTHROMBIN
(Homo
sapiens) 		5 / 9 ASP A 223
ASP A 225
TRP A 230
TYR A 232
PHE A 240
 None
 0.49A 4bvvA-3k65A:
11.4		 4bvvA-3k65A:
28.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_2
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 3k65 PROTHROMBIN
(Homo
sapiens) 		4 / 5 TYR A 242
PHE A 208
LEU A 202
PRO A 222
 None
None
BU1  A 599 ( 4.7A)
None
 1.43A 5csyB-3k65A:
undetectable		 5csyB-3k65A:
12.77