SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3k67'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_D_BRLD503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3k67 PUTATIVE DEHYDRATASE
AF1124
(Archaeoglobus
fulgidus) 		5 / 12 GLY A 119
CYH A  49
TYR A  19
LEU A  91
LEU A  87
 None
 1.24A 1fm6D-3k67A:
undetectable		 1fm6D-3k67A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_X_BRLX504_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3k67 PUTATIVE DEHYDRATASE
AF1124
(Archaeoglobus
fulgidus) 		5 / 12 GLY A 119
CYH A  49
TYR A  19
LEU A  91
LEU A  87
 None
 1.37A 1fm6X-3k67A:
undetectable		 1fm6X-3k67A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_A_J01A500_1
(ORF12)		 3k67 PUTATIVE DEHYDRATASE
AF1124
(Archaeoglobus
fulgidus) 		4 / 8 HIS A  67
ARG A  81
GLY A  80
ALA A  73
 None
 0.90A 2xfsA-3k67A:
undetectable		 2xfsA-3k67A:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_A_J01A1436_1
(ORF12)		 3k67 PUTATIVE DEHYDRATASE
AF1124
(Archaeoglobus
fulgidus) 		4 / 8 HIS A  67
ARG A  81
GLY A  80
ALA A  73
 None
 0.91A 2xh9A-3k67A:
undetectable		 2xh9A-3k67A:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HEG_A_BAXA1_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 3k67 PUTATIVE DEHYDRATASE
AF1124
(Archaeoglobus
fulgidus) 		4 / 6 VAL A 103
ILE A 138
ILE A 158
LEU A 157
 None
 0.82A 3hegA-3k67A:
undetectable		 3hegA-3k67A:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EMA_A_BRLA601_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3k67 PUTATIVE DEHYDRATASE
AF1124
(Archaeoglobus
fulgidus) 		5 / 12 GLY A 119
CYH A  49
TYR A  19
LEU A  91
LEU A  87
 None
 1.28A 4emaA-3k67A:
undetectable		 4emaA-3k67A:
19.64