SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3k6b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPK_A_ACAA80_1
(PLASMINOGEN)		 3k6b BETA-AMYLOID-LIKE
PROTEIN
(Caenorhabditis
elegans) 		4 / 6 PRO A 237
ASP A 250
ASN A 246
ASP A 249
 None
None
NT2  A 501 (-4.2A)
None
 1.12A 1hpkA-3k6bA:
undetectable		 1hpkA-3k6bA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_1
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 3k6b BETA-AMYLOID-LIKE
PROTEIN
(Caenorhabditis
elegans) 		4 / 4 ILE A 406
LEU A 403
VAL A 399
ALA A 392
 None
 0.94A 1mz9A-3k6bA:
3.0		 1mz9A-3k6bA:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IOM_A_FOLA608_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)		 3k6b BETA-AMYLOID-LIKE
PROTEIN
(Caenorhabditis
elegans) 		4 / 7 ALA A 431
PRO A 429
LEU A 414
LEU A 363
 None
 1.02A 4iomA-3k6bA:
undetectable		 4iomA-3k6bA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ4_B_ACTB403_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 3k6b BETA-AMYLOID-LIKE
PROTEIN
(Caenorhabditis
elegans) 		3 / 3 ARG A 374
ASP A 373
ARG A 402
 None
 0.68A 4wq4B-3k6bA:
2.4		 4wq4B-3k6bA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3k6b BETA-AMYLOID-LIKE
PROTEIN
(Caenorhabditis
elegans) 		4 / 6 ARG A 439
ASP A 407
ARG A 409
ILE A 410
 None
 1.18A 5a06A-3k6bA:
undetectable		 5a06A-3k6bA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D9K_F_ACTF802_0
(UNCHARACTERIZED
PROTEIN)		 3k6b BETA-AMYLOID-LIKE
PROTEIN
(Caenorhabditis
elegans) 		3 / 3 TYR A 343
ALA A 431
LEU A 417
 None
 0.75A 6d9kF-3k6bA:
undetectable		 6d9kF-3k6bA:
14.70