SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3k6e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBO_A_CAMA442_0
(CYTOCHROME P450-CAM)		 3k6e CBS DOMAIN PROTEIN
(Streptococcus
pneumoniae) 		5 / 10 THR A  89
VAL A  58
VAL A  51
VAL A  48
ILE A  61
 None
 1.42A 2qboA-3k6eA:
undetectable		 2qboA-3k6eA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN3_A_ID8A1356_1
(THYROXINE-BINDING
GLOBULIN)		 3k6e CBS DOMAIN PROTEIN
(Streptococcus
pneumoniae) 		4 / 8 LEU A 134
LYS A 135
ASN A 138
LEU A 141
 None
 0.96A 2xn3A-3k6eA:
undetectable
2xn3B-3k6eA:
undetectable		 2xn3A-3k6eA:
19.13
2xn3B-3k6eA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3k6e CBS DOMAIN PROTEIN
(Streptococcus
pneumoniae) 		4 / 8 LEU A  40
SER A 113
VAL A  58
GLY A  59
 None
 0.78A 4klrB-3k6eA:
undetectable		 4klrB-3k6eA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_0
(REGULATORY PROTEIN
TETR)		 3k6e CBS DOMAIN PROTEIN
(Streptococcus
pneumoniae) 		5 / 12 GLN A 125
LEU A  18
ILE A 127
VAL A  26
TYR A  45
 None
None
None
None
PO4  A 154 (-4.6A)
 1.39A 5vlmB-3k6eA:
undetectable		 5vlmB-3k6eA:
24.00