SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3k7d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_A_DVAA6_0
(GRAMICIDIN A)		 3k7d GLUTAMATE-AMMONIA-LI
GASE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		3 / 3 ALA A 661
VAL A 663
TRP A 662
 None
None
SO4  A  14 (-3.8A)
 0.77A 1bdwA-3k7dA:
undetectable
1bdwB-3k7dA:
undetectable		 1bdwA-3k7dA:
3.15
1bdwB-3k7dA:
3.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETB_2_T442129_1
(TRANSTHYRETIN)		 3k7d GLUTAMATE-AMMONIA-LI
GASE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		4 / 6 LEU A 472
GLU A 519
ALA A 517
LEU A 469
 None
 1.27A 1etb2-3k7dA:
undetectable		 1etb2-3k7dA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB8_0
(GRAMICIDIN A)		 3k7d GLUTAMATE-AMMONIA-LI
GASE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		4 / 5 VAL A 686
GLY A 687
VAL A 792
TRP A 694
 None
 1.13A 1tkqB-3k7dA:
undetectable		 1tkqB-3k7dA:
3.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_B_IBPB2001_1
(SERUM ALBUMIN)		 3k7d GLUTAMATE-AMMONIA-LI
GASE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		5 / 9 ILE A 852
TYR A 698
GLY A 921
ARG A 908
SER A 643
 None
 1.28A 2bxgB-3k7dA:
1.0		 2bxgB-3k7dA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 3k7d GLUTAMATE-AMMONIA-LI
GASE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		3 / 3 ARG A 865
ILE A 858
TRP A 942
 None
 1.12A 2nodB-3k7dA:
undetectable		 2nodB-3k7dA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_1
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 3k7d GLUTAMATE-AMMONIA-LI
GASE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		3 / 3 GLN A 457
THR A 466
TRP A 452
 None
 1.03A 2rctA-3k7dA:
undetectable		 2rctA-3k7dA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN1_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 3k7d GLUTAMATE-AMMONIA-LI
GASE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		5 / 11 PHE A 771
VAL A 788
TYR A 688
ILE A 705
PHE A 803
 None
 1.46A 2vn1A-3k7dA:
undetectable		 2vn1A-3k7dA:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 3k7d GLUTAMATE-AMMONIA-LI
GASE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		4 / 8 THR A 524
LEU A 555
GLU A 918
SER A 562
 None
 0.97A 2zw9A-3k7dA:
undetectable		 2zw9A-3k7dA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3k7d GLUTAMATE-AMMONIA-LI
GASE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		4 / 5 ILE A 882
ARG A 808
MET A 811
THR A 812
 None
SO4  A   3 (-4.1A)
None
None
 1.29A 3abkN-3k7dA:
undetectable
3abkW-3k7dA:
undetectable		 3abkN-3k7dA:
21.52
3abkW-3k7dA:
7.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3k7d GLUTAMATE-AMMONIA-LI
GASE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		4 / 6 ILE A 484
ILE A 496
LEU A 455
MET A 508
 None
 1.16A 3adsA-3k7dA:
undetectable		 3adsA-3k7dA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GY3_A_PNTA246_0
(CATIONIC TRYPSIN)		 3k7d GLUTAMATE-AMMONIA-LI
GASE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		5 / 11 LEU A 755
SER A 877
GLN A 860
GLY A 689
GLY A 692
 None
None
None
SO4  A  16 ( 3.9A)
None
 1.20A 3gy3A-3k7dA:
undetectable		 3gy3A-3k7dA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3k7d GLUTAMATE-AMMONIA-LI
GASE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		3 / 3 LEU A 919
PRO A 920
LEU A 914
 None
 0.56A 3hcrA-3k7dA:
undetectable		 3hcrA-3k7dA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP202_1
(PROTEIN S100-A4)		 3k7d GLUTAMATE-AMMONIA-LI
GASE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		5 / 12 GLU A 578
LEU A 585
ASP A 581
LEU A 626
PHE A 548
 None
 1.19A 3ko0M-3k7dA:
undetectable
3ko0N-3k7dA:
undetectable
3ko0O-3k7dA:
undetectable
3ko0P-3k7dA:
undetectable		 3ko0M-3k7dA:
12.83
3ko0N-3k7dA:
12.83
3ko0O-3k7dA:
12.83
3ko0P-3k7dA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3k7d GLUTAMATE-AMMONIA-LI
GASE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		3 / 3 ARG A 865
ILE A 858
TRP A 942
 None
 1.09A 3nw2A-3k7dA:
undetectable		 3nw2A-3k7dA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3k7d GLUTAMATE-AMMONIA-LI
GASE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		3 / 3 ARG A 865
ILE A 858
TRP A 942
 None
 1.11A 3nw2B-3k7dA:
undetectable		 3nw2B-3k7dA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_B_CVIB301_0
(PUTATIVE REGULATORY
PROTEIN)		 3k7d GLUTAMATE-AMMONIA-LI
GASE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		5 / 12 LEU A 532
ILE A 556
ILE A 535
LEU A 576
LEU A 585
 None
 1.10A 3vw1B-3k7dA:
undetectable		 3vw1B-3k7dA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3k7d GLUTAMATE-AMMONIA-LI
GASE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		4 / 6 ILE A 882
ARG A 808
MET A 811
THR A 812
 None
SO4  A   3 (-4.1A)
None
None
 1.17A 3wg7A-3k7dA:
undetectable
3wg7J-3k7dA:
undetectable		 3wg7A-3k7dA:
21.52
3wg7J-3k7dA:
7.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV1_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 3k7d GLUTAMATE-AMMONIA-LI
GASE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		3 / 3 LYS A 872
LYS A 870
PRO A 871
 None
 1.18A 4dv1L-3k7dA:
undetectable		 4dv1L-3k7dA:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_D_ESTD600_1
(ESTROGEN RECEPTOR
BETA)		 3k7d GLUTAMATE-AMMONIA-LI
GASE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		5 / 12 LEU A 598
ALA A 652
ILE A 628
LEU A 625
HIS A 645
 None
 0.90A 4j24D-3k7dA:
undetectable		 4j24D-3k7dA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)		 3k7d GLUTAMATE-AMMONIA-LI
GASE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		4 / 8 GLN A 917
VAL A 523
THR A 524
ARG A 527
 None
SO4  A   5 ( 4.7A)
None
SO4  A   5 (-3.7A)
 0.83A 4lnwA-3k7dA:
undetectable		 4lnwA-3k7dA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T44A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 3k7d GLUTAMATE-AMMONIA-LI
GASE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		4 / 6 GLN A 917
VAL A 523
THR A 524
ARG A 527
 None
SO4  A   5 ( 4.7A)
None
SO4  A   5 (-3.7A)
 0.93A 4lnxA-3k7dA:
undetectable		 4lnxA-3k7dA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_G_TMQG202_1
(DIHYDROFOLATE
REDUCTASE)		 3k7d GLUTAMATE-AMMONIA-LI
GASE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		5 / 12 ALA A 560
LEU A 585
PRO A 582
ILE A 565
THR A 524
 None
 1.08A 4m2xG-3k7dA:
undetectable		 4m2xG-3k7dA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 3k7d GLUTAMATE-AMMONIA-LI
GASE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		5 / 12 GLY A 689
GLY A 692
THR A 874
GLY A 687
VAL A 686
 SO4  A  16 ( 3.9A)
None
SO4  A   3 (-3.7A)
None
None
 0.94A 4o3fA-3k7dA:
undetectable		 4o3fA-3k7dA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZOW_A_CLMA500_0
(MULTIDRUG
TRANSPORTER MDFA)		 3k7d GLUTAMATE-AMMONIA-LI
GASE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		5 / 11 LEU A 504
LEU A 579
LEU A 531
LEU A 532
ILE A 535
 None
 0.96A 4zowA-3k7dA:
undetectable		 4zowA-3k7dA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A5Z_C_WJZC304_0
(BETA-LACTAMASE NDM-1)		 3k7d GLUTAMATE-AMMONIA-LI
GASE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		4 / 7 HIS A 674
CYH A 710
GLY A 682
HIS A 708
 None
 1.26A 5a5zC-3k7dA:
undetectable		 5a5zC-3k7dA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3k7d GLUTAMATE-AMMONIA-LI
GASE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		5 / 12 LEU A 702
MET A 736
GLY A 759
GLY A 689
PHE A 706
 None
None
None
SO4  A  16 ( 3.9A)
None
 1.11A 5d4uA-3k7dA:
undetectable		 5d4uA-3k7dA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3k7d GLUTAMATE-AMMONIA-LI
GASE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		4 / 7 ILE A 882
ARG A 808
MET A 811
THR A 812
 None
SO4  A   3 (-4.1A)
None
None
 0.81A 5xdqA-3k7dA:
undetectable
5xdqJ-3k7dA:
undetectable		 5xdqA-3k7dA:
21.52
5xdqJ-3k7dA:
7.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCN_A_8LXA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3k7d GLUTAMATE-AMMONIA-LI
GASE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		4 / 6 CYH A 559
SER A 557
HIS A 554
TYR A 586
 None
SO4  A  12 (-3.4A)
None
None
 1.40A 5ycnA-3k7dA:
undetectable		 5ycnA-3k7dA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA410_0
(UNCHARACTERIZED
PROTEIN KDOO)		 3k7d GLUTAMATE-AMMONIA-LI
GASE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		4 / 4 GLY A 687
LEU A 691
VAL A 793
GLU A 651
 None
 1.40A 5yw0A-3k7dA:
undetectable		 5yw0A-3k7dA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3k7d GLUTAMATE-AMMONIA-LI
GASE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		4 / 6 ILE A 882
ARG A 808
MET A 811
THR A 812
 None
SO4  A   3 (-4.1A)
None
None
 1.09A 6nmfN-3k7dA:
undetectable
6nmfW-3k7dA:
undetectable		 6nmfN-3k7dA:
21.52
6nmfW-3k7dA:
7.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3k7d GLUTAMATE-AMMONIA-LI
GASE
ADENYLYLTRANSFERASE
(Escherichia
coli) 		4 / 5 LEU A 617
GLN A 619
PHE A 620
PHE A 739
 None
 1.42A 6nmpP-3k7dA:
undetectable
6nmpW-3k7dA:
undetectable		 6nmpP-3k7dA:
18.88
6nmpW-3k7dA:
7.47