SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3k7l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_E_SNLE5001_1
(MINERALOCORTICOID
RECEPTOR)		 3k7l ATRAGIN
(Naja
atra) 		5 / 12 ASN A 293
ALA A 294
LEU A 297
MET A 239
LEU A 252
 None
 1.42A 2oaxE-3k7lA:
undetectable		 2oaxE-3k7lA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_A_HAEA502_1
(COLLAGENASE 3)		 3k7l ATRAGIN
(Naja
atra) 		4 / 6 LEU A 274
GLU A 342
HIS A 345
HIS A 351
 None
 0.88A 2ow9A-3k7lA:
8.3		 2ow9A-3k7lA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA3_0
(FERROCHELATASE)		 3k7l ATRAGIN
(Naja
atra) 		3 / 3 PRO A 476
LEU A 478
ARG A 463
 None
 0.89A 3aqiA-3k7lA:
4.6		 3aqiA-3k7lA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_A_ERYA195_1
(REPRESSOR PROTEIN
MPHR(A))		 3k7l ATRAGIN
(Naja
atra) 		4 / 5 ASN A 293
ASN A 240
HIS A 249
ALA A 251
 None
 1.40A 3frqA-3k7lA:
undetectable		 3frqA-3k7lA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_B_ERYB195_1
(REPRESSOR PROTEIN
MPHR(A))		 3k7l ATRAGIN
(Naja
atra) 		4 / 7 ASN A 293
ASN A 240
HIS A 249
ALA A 251
 None
 1.40A 3frqB-3k7lA:
undetectable		 3frqB-3k7lA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_A_HAEA272_1
(COLLAGENASE 3)		 3k7l ATRAGIN
(Naja
atra) 		4 / 5 LEU A 274
GLU A 342
HIS A 345
HIS A 351
 None
 0.94A 3kecA-3k7lA:
8.3		 3kecA-3k7lA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L2V_A_RLTA397_1
(INTEGRASE)		 3k7l ATRAGIN
(Naja
atra) 		4 / 7 ASP A 489
ASP A 474
PRO A 476
GLU A 477
 CA  A 702 (-3.1A)
CA  A 702 (-2.9A)
None
CA  A 702 (-2.3A)
 1.17A 3l2vA-3k7lA:
undetectable		 3l2vA-3k7lA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3O_A_DLUA399_1
(PFV INTEGRASE)		 3k7l ATRAGIN
(Naja
atra) 		4 / 7 ASP A 489
ASP A 474
PRO A 476
GLU A 477
 CA  A 702 (-3.1A)
CA  A 702 (-2.9A)
None
CA  A 702 (-2.3A)
 1.22A 3s3oA-3k7lA:
undetectable		 3s3oA-3k7lA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_A_HAEA1273_1
(COLLAGENASE 3)		 3k7l ATRAGIN
(Naja
atra) 		4 / 6 LEU A 274
GLU A 342
HIS A 345
HIS A 351
 None
 0.92A 4a7bA-3k7lA:
8.0		 4a7bA-3k7lA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G10_A_ACTA301_0
(GLUTATHIONE
S-TRANSFERASE
HOMOLOG)		 3k7l ATRAGIN
(Naja
atra) 		4 / 6 PRO A 393
ILE A 207
TYR A 387
PHE A 248
 None
 1.13A 4g10A-3k7lA:
undetectable		 4g10A-3k7lA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA503_1
(CYTOCHROME P450 2C9)		 3k7l ATRAGIN
(Naja
atra) 		4 / 5 PRO A 591
GLY A 592
THR A 593
LYS A 594
 None
 1.02A 5x23A-3k7lA:
undetectable		 5x23A-3k7lA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X24_A_LSNA503_1
(CYTOCHROME P450 2C9)		 3k7l ATRAGIN
(Naja
atra) 		4 / 6 PRO A 591
GLY A 592
THR A 593
LYS A 594
 None
 0.98A 5x24A-3k7lA:
undetectable		 5x24A-3k7lA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA502_1
(CYTOCHROME P450 2C9)		 3k7l ATRAGIN
(Naja
atra) 		4 / 6 PRO A 591
GLY A 592
THR A 593
LYS A 594
 None
 0.93A 5xxiA-3k7lA:
undetectable		 5xxiA-3k7lA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_B_IXXB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 3k7l ATRAGIN
(Naja
atra) 		4 / 5 ARG A 467
ALA A 203
TYR A 200
ILE A 396
 None
 1.38A 6g9bA-3k7lA:
1.4
6g9bB-3k7lA:
undetectable		 6g9bA-3k7lA:
15.00
6g9bB-3k7lA:
13.55