SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3k7x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1F9G_A_ASCA950_0
(HYALURONATE LYASE)		 3k7x LIN0763 PROTEIN
(Listeria
innocua) 		4 / 7 ARG A 273
ASN A  97
TYR A 324
ASN A  78
 None
 1.18A 1f9gA-3k7xA:
6.3		 1f9gA-3k7xA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_A_SAMA500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 3k7x LIN0763 PROTEIN
(Listeria
innocua) 		4 / 7 ASP A 195
PHE A 211
ASN A 214
ARG A 199
 None
 1.45A 1rqpB-3k7xA:
undetectable		 1rqpB-3k7xA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_A_NFZA1219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3k7x LIN0763 PROTEIN
(Listeria
innocua) 		4 / 8 TYR A 274
PHE A 275
GLU A 224
GLY A 220
 None
 1.07A 1ykiA-3k7xA:
undetectable
1ykiB-3k7xA:
undetectable		 1ykiA-3k7xA:
21.91
1ykiB-3k7xA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_B_NFZB2219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3k7x LIN0763 PROTEIN
(Listeria
innocua) 		4 / 8 TYR A 274
PHE A 275
GLU A 224
GLY A 220
 None
 1.08A 1ykiA-3k7xA:
undetectable
1ykiB-3k7xA:
undetectable		 1ykiA-3k7xA:
21.91
1ykiB-3k7xA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_D_NFZD4219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3k7x LIN0763 PROTEIN
(Listeria
innocua) 		4 / 8 TYR A 274
PHE A 275
GLU A 224
GLY A 220
 None
 1.09A 1ykiC-3k7xA:
undetectable
1ykiD-3k7xA:
undetectable		 1ykiC-3k7xA:
21.91
1ykiD-3k7xA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B235_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 3k7x LIN0763 PROTEIN
(Listeria
innocua) 		4 / 6 PHE A 211
PHE A 267
GLY A 261
GLY A 262
 None
 0.99A 2qr2A-3k7xA:
undetectable
2qr2B-3k7xA:
undetectable		 2qr2A-3k7xA:
20.33
2qr2B-3k7xA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 3k7x LIN0763 PROTEIN
(Listeria
innocua) 		4 / 5 GLY A 261
GLY A 262
PHE A 211
PHE A 267
 None
 1.00A 2qr2A-3k7xA:
undetectable
2qr2B-3k7xA:
undetectable		 2qr2A-3k7xA:
20.33
2qr2B-3k7xA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_1
(PROTEASE)		 3k7x LIN0763 PROTEIN
(Listeria
innocua) 		5 / 9 LEU A  56
ASP A  57
GLY A 269
ILE A 270
VAL A  52
 None
 1.19A 2r5qA-3k7xA:
undetectable		 2r5qA-3k7xA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_1
(PROTEASE)		 3k7x LIN0763 PROTEIN
(Listeria
innocua) 		5 / 9 LEU A  56
ASP A  57
GLY A 269
ILE A 270
VAL A  52
 None
 1.19A 2r5qC-3k7xA:
undetectable		 2r5qC-3k7xA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		 3k7x LIN0763 PROTEIN
(Listeria
innocua) 		4 / 6 ALA A  58
LEU A  60
ALA A 107
THR A 108
 None
 0.89A 3b6hA-3k7xA:
undetectable		 3b6hA-3k7xA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		 3k7x LIN0763 PROTEIN
(Listeria
innocua) 		4 / 6 ALA A  58
LEU A  60
ALA A 107
THR A 108
 None
 0.92A 3b6hB-3k7xA:
undetectable		 3b6hB-3k7xA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZG_B_NCAB302_0
(ADP-RIBOSYL CYCLASE
1)		 3k7x LIN0763 PROTEIN
(Listeria
innocua) 		4 / 7 TRP A 121
LEU A 124
ASP A 126
THR A 178
 None
 1.29A 3dzgB-3k7xA:
undetectable		 3dzgB-3k7xA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_2
(PROTEIN S100-A4)		 3k7x LIN0763 PROTEIN
(Listeria
innocua) 		3 / 3 GLU A 281
LEU A 278
ASP A 277
 None
 0.42A 3ko0T-3k7xA:
undetectable		 3ko0T-3k7xA:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2O_B_CLQB1079_0
(SAPOSIN-B)		 3k7x LIN0763 PROTEIN
(Listeria
innocua) 		3 / 3 MET A   1
GLU A   5
LEU A   9
 None
 0.80A 4v2oB-3k7xA:
undetectable		 4v2oB-3k7xA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 3k7x LIN0763 PROTEIN
(Listeria
innocua) 		4 / 5 GLY A 261
TYR A 324
SER A 325
ASP A 263
 None
 0.83A 4xueA-3k7xA:
undetectable		 4xueA-3k7xA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EFN_A_SAMA501_0
(SPORULATION KILLING
FACTOR MATURATION
PROTEIN SKFB)		 3k7x LIN0763 PROTEIN
(Listeria
innocua) 		5 / 11 GLU A 258
SER A 245
THR A 241
LEU A 223
ALA A 221
 None
 1.42A 6efnA-3k7xA:
undetectable		 6efnA-3k7xA:
24.01