SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3k80'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ESW_A_ACRA652_1 (AMYLOMALTASE)	3k80	ANTIBODY (Lama glama)	4 / 6	TYR A 111 GLY A 98 GLY A 102 TYR A 101	None	0.95A	1eswA-3k80A: undetectable	1eswA-3k80A: 13.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3QXT_A_MTXA2000_1 (ANTI-METHOTREXATE CDR1-3 GRAFT VHH)	3k80	ANTIBODY (Lama glama)	5 / 12	ALA A 24 MET A 34 ARG A 72 ASN A 77 VAL A 79	None	0.93A	3qxtA-3k80A: 22.2	3qxtA-3k80A: 70.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3QXT_A_MTXA2000_1 (ANTI-METHOTREXATE CDR1-3 GRAFT VHH)	3k80	ANTIBODY (Lama glama)	5 / 12	VAL A 2 ALA A 24 ARG A 72 ASN A 77 VAL A 79	None	1.06A	3qxtA-3k80A: 22.2	3qxtA-3k80A: 70.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XT8_A_TMQA302_1 (RV2671)	3k80	ANTIBODY (Lama glama)	5 / 12	SER A 105 GLY A 104 ALA A 50 PHE A 37 GLU A 110	None	1.29A	4xt8A-3k80A: undetectable	4xt8A-3k80A: 21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ECM_D_LEUD602_0 (JASMONIC ACID-AMIDO SYNTHETASE JAR1)	3k80	ANTIBODY (Lama glama)	4 / 7	ALA A 92 THR A 91 VAL A 120 GLU A 89	None	0.76A	5ecmD-3k80A: undetectable	5ecmD-3k80A: 13.07

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1ESW_A_ACRA652_1","AMYLOMALTASE","3k80","ANTIBODY","Lama glama",4,"TYR A 111;GLY A  98;GLY A 102;TYR A 101","None","0.95A","1eswA-3k80A:undetectable","1eswA-3k80A:13.09"],["3QXT_A_MTXA2000_1","ANTI-METHOTREXATE CDR1-3 GRAFT VHH","3k80","ANTIBODY","Lama glama",5,"ALA A  24;MET A  34;ARG A  72;ASN A  77;VAL A  79","None","0.93A","3qxtA-3k80A:22.2","3qxtA-3k80A:70.16"],["3QXT_A_MTXA2000_1","ANTI-METHOTREXATE CDR1-3 GRAFT VHH","3k80","ANTIBODY","Lama glama",5,"VAL A   2;ALA A  24;ARG A  72;ASN A  77;VAL A  79","None","1.06A","3qxtA-3k80A:22.2","3qxtA-3k80A:70.16"],["4XT8_A_TMQA302_1","RV2671","3k80","ANTIBODY","Lama glama",5,"SER A 105;GLY A 104;ALA A  50;PHE A  37;GLU A 110","None","1.29A","4xt8A-3k80A:undetectable","4xt8A-3k80A:21.62"],["5ECM_D_LEUD602_0","JASMONIC ACID-AMIDO SYNTHETASE JAR1","3k80","ANTIBODY","Lama glama",4,"ALA A  92;THR A  91;VAL A 120;GLU A  89","None","0.76A","5ecmD-3k80A:undetectable","5ecmD-3k80A:13.07"]]