SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3k81'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TZC_D_EF2D505_1
(PROTEIN CEREBLON)		 3k81 SINGLE STRAND
ANTIBODY VHH DOMAIN
(Lama
glama) 		4 / 8 THR A 115
TRP A  36
TRP A  34
PHE A  29
 None
 1.16A 4tzcB-3k81A:
undetectable
4tzcD-3k81A:
undetectable		 4tzcB-3k81A:
19.55
4tzcD-3k81A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TZU_B_Y70B505_1
(PROTEIN CEREBLON)		 3k81 SINGLE STRAND
ANTIBODY VHH DOMAIN
(Lama
glama) 		4 / 7 TRP A  34
PHE A  29
THR A 115
TRP A  36
 None
 1.18A 4tzuB-3k81A:
undetectable
4tzuC-3k81A:
0.0		 4tzuB-3k81A:
19.40
4tzuC-3k81A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TZU_C_Y70C504_1
(PROTEIN CEREBLON)		 3k81 SINGLE STRAND
ANTIBODY VHH DOMAIN
(Lama
glama) 		4 / 7 THR A 115
TRP A  36
TRP A  34
PHE A  29
 None
 1.13A 4tzuB-3k81A:
undetectable
4tzuC-3k81A:
undetectable		 4tzuB-3k81A:
19.40
4tzuC-3k81A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ICX_F_SC2F1_1
(CETUXIMAB FAB LIGHT
CHAIN
MEDITOPE)		 3k81 MP18 RNA EDITING
COMPLEX PROTEIN
(Trypanosoma
brucei) 		3 / 3 VAL C  95
GLN C  46
CYH C  74
 None
 0.68A 5icxC-3k81C:
undetectable
5icxF-3k81C:
undetectable		 5icxC-3k81C:
21.43
5icxF-3k81C:
7.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YIZ_G_EF2G501_1
(PROTEIN CEREBLON)		 3k81 SINGLE STRAND
ANTIBODY VHH DOMAIN
(Lama
glama) 		4 / 7 TRP A  34
PHE A  29
THR A 115
TRP A  36
 None
 1.09A 5yizG-3k81A:
0.0
5yizY-3k81A:
0.0		 5yizG-3k81A:
18.60
5yizY-3k81A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YIZ_K_EF2K501_1
(PROTEIN CEREBLON)		 3k81 SINGLE STRAND
ANTIBODY VHH DOMAIN
(Lama
glama) 		4 / 7 TRP A  34
PHE A  29
THR A 115
TRP A  36
 None
 1.16A 5yizk-3k81A:
0.0
5yizt-3k81A:
0.0		 5yizk-3k81A:
18.60
5yizt-3k81A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YIZ_T_EF2T501_1
(PROTEIN CEREBLON)		 3k81 SINGLE STRAND
ANTIBODY VHH DOMAIN
(Lama
glama) 		4 / 7 THR A 115
TRP A  36
TRP A  34
PHE A  29
 None
 1.10A 5yizk-3k81A:
undetectable
5yizt-3k81A:
0.0		 5yizk-3k81A:
18.60
5yizt-3k81A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YIZ_Y_EF2Y501_1
(PROTEIN CEREBLON)		 3k81 SINGLE STRAND
ANTIBODY VHH DOMAIN
(Lama
glama) 		4 / 7 THR A 115
TRP A  36
TRP A  34
PHE A  29
 None
 1.18A 5yizG-3k81A:
0.0
5yizY-3k81A:
0.0		 5yizG-3k81A:
18.60
5yizY-3k81A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ0_G_EF2G501_1
(PROTEIN CEREBLON)		 3k81 SINGLE STRAND
ANTIBODY VHH DOMAIN
(Lama
glama) 		4 / 7 TRP A  34
PHE A  29
THR A 115
TRP A  36
 None
 1.09A 5yj0G-3k81A:
0.0
5yj0Y-3k81A:
0.0		 5yj0G-3k81A:
18.60
5yj0Y-3k81A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ0_K_EF2K501_1
(PROTEIN CEREBLON)		 3k81 SINGLE STRAND
ANTIBODY VHH DOMAIN
(Lama
glama) 		4 / 7 TRP A  34
PHE A  29
THR A 115
TRP A  36
 None
 1.18A 5yj0k-3k81A:
0.0
5yj0t-3k81A:
0.0		 5yj0k-3k81A:
18.60
5yj0t-3k81A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ0_T_EF2T501_1
(PROTEIN CEREBLON)		 3k81 SINGLE STRAND
ANTIBODY VHH DOMAIN
(Lama
glama) 		4 / 7 THR A 115
TRP A  36
TRP A  34
PHE A  29
 None
 1.11A 5yj0k-3k81A:
0.0
5yj0t-3k81A:
0.0		 5yj0k-3k81A:
18.60
5yj0t-3k81A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ0_Y_EF2Y501_1
(PROTEIN CEREBLON)		 3k81 SINGLE STRAND
ANTIBODY VHH DOMAIN
(Lama
glama) 		4 / 7 THR A 115
TRP A  36
TRP A  34
PHE A  29
 None
 1.17A 5yj0G-3k81A:
0.0
5yj0Y-3k81A:
0.0		 5yj0G-3k81A:
18.60
5yj0Y-3k81A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ1_G_6ELG501_0
(PROTEIN CEREBLON)		 3k81 SINGLE STRAND
ANTIBODY VHH DOMAIN
(Lama
glama) 		4 / 8 TRP A  34
PHE A  29
THR A 115
TRP A  36
 None
 1.08A 5yj1G-3k81A:
undetectable
5yj1Y-3k81A:
undetectable		 5yj1G-3k81A:
19.12
5yj1Y-3k81A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ1_K_6ELK501_0
(PROTEIN CEREBLON)		 3k81 SINGLE STRAND
ANTIBODY VHH DOMAIN
(Lama
glama) 		4 / 7 TRP A  34
PHE A  29
THR A 115
TRP A  36
 None
 1.18A 5yj1k-3k81A:
undetectable
5yj1t-3k81A:
0.0		 5yj1k-3k81A:
19.12
5yj1t-3k81A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ1_T_6ELT501_0
(PROTEIN CEREBLON)		 3k81 SINGLE STRAND
ANTIBODY VHH DOMAIN
(Lama
glama) 		4 / 8 THR A 115
TRP A  36
TRP A  34
PHE A  29
 None
 1.08A 5yj1k-3k81A:
undetectable
5yj1t-3k81A:
undetectable		 5yj1k-3k81A:
19.12
5yj1t-3k81A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ1_Y_6ELY501_0
(PROTEIN CEREBLON)		 3k81 SINGLE STRAND
ANTIBODY VHH DOMAIN
(Lama
glama) 		4 / 7 THR A 115
TRP A  36
TRP A  34
PHE A  29
 None
 1.16A 5yj1G-3k81A:
undetectable
5yj1Y-3k81A:
0.0		 5yj1G-3k81A:
19.12
5yj1Y-3k81A:
19.12