SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3k85'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_2
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 3k85 D-GLYCERO-D-MANNO-HE
PTOSE 1-PHOSPHATE
KINASE
(Bacteroides
thetaiotaomicron) 		4 / 8 ALA A 288
PHE A 304
VAL A 306
VAL A 199
 None
 0.54A 1epbB-3k85A:
undetectable		 1epbB-3k85A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3k85 D-GLYCERO-D-MANNO-HE
PTOSE 1-PHOSPHATE
KINASE
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A 151
GLU A  72
CYH A  61
ALA A  77
ALA A  56
 None
 1.16A 2bm9D-3k85A:
undetectable		 2bm9D-3k85A:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3k85 D-GLYCERO-D-MANNO-HE
PTOSE 1-PHOSPHATE
KINASE
(Bacteroides
thetaiotaomicron) 		4 / 4 LEU A 132
PRO A 133
LEU A 134
ARG A  86
 None
 1.28A 3hcoA-3k85A:
undetectable		 3hcoA-3k85A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_D_SUED1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 3k85 D-GLYCERO-D-MANNO-HE
PTOSE 1-PHOSPHATE
KINASE
(Bacteroides
thetaiotaomicron) 		4 / 5 TYR A 161
LEU A 245
LYS A 242
ARG A  10
 None
 1.10A 3sudD-3k85A:
undetectable		 3sudD-3k85A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_A_RTZA2_1
(CYTOCHROME P450 2D6)		 3k85 D-GLYCERO-D-MANNO-HE
PTOSE 1-PHOSPHATE
KINASE
(Bacteroides
thetaiotaomicron) 		5 / 11 THR A 241
VAL A 305
LEU A 245
VAL A 191
PHE A 168
 None
 1.22A 3tbgA-3k85A:
2.7		 3tbgA-3k85A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_I_ZPCI1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3k85 D-GLYCERO-D-MANNO-HE
PTOSE 1-PHOSPHATE
KINASE
(Bacteroides
thetaiotaomicron) 		4 / 6 ILE A 180
PHE A 173
TYR A 137
VAL A 120
 None
 1.22A 4a97I-3k85A:
undetectable		 4a97I-3k85A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_B_STRB601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3k85 D-GLYCERO-D-MANNO-HE
PTOSE 1-PHOSPHATE
KINASE
(Bacteroides
thetaiotaomicron) 		4 / 5 ILE A  36
LEU A  11
GLU A 195
VAL A 250
 None
 1.00A 4nkxB-3k85A:
undetectable		 4nkxB-3k85A:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3k85 D-GLYCERO-D-MANNO-HE
PTOSE 1-PHOSPHATE
KINASE
(Bacteroides
thetaiotaomicron) 		5 / 12 THR A 139
ALA A 143
GLY A 166
ALA A 163
THR A  35
 None
 1.26A 4qvnV-3k85A:
undetectable
4qvnb-3k85A:
undetectable		 4qvnV-3k85A:
22.86
4qvnb-3k85A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3k85 D-GLYCERO-D-MANNO-HE
PTOSE 1-PHOSPHATE
KINASE
(Bacteroides
thetaiotaomicron) 		5 / 12 THR A 139
ALA A 143
GLY A 334
ALA A 163
THR A  35
 None
 1.10A 4qvnV-3k85A:
undetectable
4qvnb-3k85A:
undetectable		 4qvnV-3k85A:
22.86
4qvnb-3k85A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3k85 D-GLYCERO-D-MANNO-HE
PTOSE 1-PHOSPHATE
KINASE
(Bacteroides
thetaiotaomicron) 		5 / 12 THR A 139
ALA A 143
GLY A 166
ALA A 163
THR A  35
 None
 1.25A 4qvnH-3k85A:
undetectable
4qvnN-3k85A:
undetectable		 4qvnH-3k85A:
22.86
4qvnN-3k85A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3k85 D-GLYCERO-D-MANNO-HE
PTOSE 1-PHOSPHATE
KINASE
(Bacteroides
thetaiotaomicron) 		5 / 12 THR A 139
ALA A 143
GLY A 334
ALA A 163
THR A  35
 None
 1.09A 4qvnH-3k85A:
undetectable
4qvnN-3k85A:
undetectable		 4qvnH-3k85A:
22.86
4qvnN-3k85A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RV6_A_RPBA1103_1
(POLY [ADP-RIBOSE]
POLYMERASE 1)		 3k85 D-GLYCERO-D-MANNO-HE
PTOSE 1-PHOSPHATE
KINASE
(Bacteroides
thetaiotaomicron) 		5 / 11 GLN A 160
GLU A 147
GLY A 109
ALA A 106
SER A 110
 None
 1.49A 4rv6A-3k85A:
undetectable		 4rv6A-3k85A:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RV6_B_RPBB1103_1
(POLY [ADP-RIBOSE]
POLYMERASE 1)		 3k85 D-GLYCERO-D-MANNO-HE
PTOSE 1-PHOSPHATE
KINASE
(Bacteroides
thetaiotaomicron) 		5 / 11 GLN A 160
GLU A 147
GLY A 109
ALA A 106
SER A 110
 None
 1.49A 4rv6B-3k85A:
undetectable		 4rv6B-3k85A:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 3k85 D-GLYCERO-D-MANNO-HE
PTOSE 1-PHOSPHATE
KINASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ALA A 317
ASN A 320
LEU A 321
 None
 0.36A 5i1nC-3k85A:
undetectable		 5i1nC-3k85A:
8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 3k85 D-GLYCERO-D-MANNO-HE
PTOSE 1-PHOSPHATE
KINASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ALA A 317
ASN A 320
LEU A 321
 None
 0.22A 5i1nB-3k85A:
undetectable		 5i1nB-3k85A:
8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 3k85 D-GLYCERO-D-MANNO-HE
PTOSE 1-PHOSPHATE
KINASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ALA A 317
ASN A 320
LEU A 321
 None
 0.29A 5i1oC-3k85A:
undetectable		 5i1oC-3k85A:
8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_H_DVAH9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 3k85 D-GLYCERO-D-MANNO-HE
PTOSE 1-PHOSPHATE
KINASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ALA A 317
ASN A 320
LEU A 321
 None
 0.31A 5i1oA-3k85A:
undetectable		 5i1oA-3k85A:
8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 3k85 D-GLYCERO-D-MANNO-HE
PTOSE 1-PHOSPHATE
KINASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ALA A 317
ASN A 320
LEU A 321
 None
 0.21A 5i1pA-3k85A:
undetectable		 5i1pA-3k85A:
8.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 3k85 D-GLYCERO-D-MANNO-HE
PTOSE 1-PHOSPHATE
KINASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ALA A 317
ASN A 320
LEU A 321
 None
 0.26A 5i1pD-3k85A:
undetectable		 5i1pD-3k85A:
8.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_B_BO2B201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 3k85 D-GLYCERO-D-MANNO-HE
PTOSE 1-PHOSPHATE
KINASE
(Bacteroides
thetaiotaomicron) 		5 / 12 THR A 139
ALA A 143
GLY A 166
ALA A 163
THR A  35
 None
 1.25A 6hwdV-3k85A:
undetectable
6hwdb-3k85A:
undetectable		 6hwdV-3k85A:
13.79
6hwdb-3k85A:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_B_BO2B201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 3k85 D-GLYCERO-D-MANNO-HE
PTOSE 1-PHOSPHATE
KINASE
(Bacteroides
thetaiotaomicron) 		5 / 12 THR A 139
ALA A 143
GLY A 334
ALA A 163
THR A  35
 None
 1.07A 6hwdV-3k85A:
undetectable
6hwdb-3k85A:
undetectable		 6hwdV-3k85A:
13.79
6hwdb-3k85A:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_N_BO2N201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 3k85 D-GLYCERO-D-MANNO-HE
PTOSE 1-PHOSPHATE
KINASE
(Bacteroides
thetaiotaomicron) 		5 / 12 THR A 139
ALA A 143
GLY A 166
ALA A 163
THR A  35
 None
 1.25A 6hwdH-3k85A:
undetectable
6hwdN-3k85A:
undetectable		 6hwdH-3k85A:
13.79
6hwdN-3k85A:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_N_BO2N201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 3k85 D-GLYCERO-D-MANNO-HE
PTOSE 1-PHOSPHATE
KINASE
(Bacteroides
thetaiotaomicron) 		5 / 12 THR A 139
ALA A 143
GLY A 334
ALA A 163
THR A  35
 None
 1.08A 6hwdH-3k85A:
undetectable
6hwdN-3k85A:
undetectable		 6hwdH-3k85A:
13.79
6hwdN-3k85A:
13.56