SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3k8p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_F_FUAF704_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3k8p DSL1
(Kluyveromyces
lactis) 		5 / 11 THR C 466
LEU C 482
VAL C 476
PHE C 430
VAL C 486
 None
 1.27A 1q23F-3k8pC:
undetectable		 1q23F-3k8pC:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA3_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 3k8p DSL1
(Kluyveromyces
lactis) 		5 / 12 ALA C 634
ILE C 677
ARG C 681
ILE C 660
THR C 633
 None
 1.04A 1ra3A-3k8pC:
undetectable		 1ra3A-3k8pC:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S8F_A_BEZA1501_0
(RAS-RELATED PROTEIN
RAB-9A)		 3k8p PROTEIN TRANSPORT
PROTEIN SEC39
(Saccharomyces
cerevisiae) 		4 / 5 ILE D 197
ARG D 175
TRP D 185
LEU D 218
 None
 1.25A 1s8fA-3k8pD:
undetectable
1s8fB-3k8pD:
undetectable		 1s8fA-3k8pD:
12.34
1s8fB-3k8pD:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SKX_A_RFPA1_2
(ORPHAN NUCLEAR
RECEPTOR PXR)		 3k8p DSL1
PROTEIN TRANSPORT
PROTEIN SEC39
(Kluyveromyces
lactis;
Saccharomyces
cerevisiae) 		4 / 5 PHE C 438
LEU D 651
MET C 344
LEU C 458
 None
 1.45A 1skxA-3k8pC:
undetectable		 1skxA-3k8pC:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_C_TFPC208_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3k8p PROTEIN TRANSPORT
PROTEIN SEC39
(Saccharomyces
cerevisiae) 		4 / 5 PHE D 252
LEU D 305
PHE D 236
SER D 270
 None
 1.25A 1wrlC-3k8pD:
undetectable		 1wrlC-3k8pD:
8.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_A_STRA1001_2
(MINERALOCORTICOID
RECEPTOR)		 3k8p PROTEIN TRANSPORT
PROTEIN SEC39
(Saccharomyces
cerevisiae) 		4 / 4 LEU D 385
LEU D 362
SER D 360
LEU D 356
 None
 1.01A 1ya3A-3k8pD:
undetectable		 1ya3A-3k8pD:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_2
(TUBULIN ALPHA CHAIN)		 3k8p DSL1
(Kluyveromyces
lactis) 		4 / 5 VAL C 522
ASN C 523
VAL C 578
ILE C 573
 None
 1.04A 1z2bC-3k8pC:
undetectable		 1z2bC-3k8pC:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OD9_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 3k8p PROTEIN TRANSPORT
PROTEIN SEC39
(Saccharomyces
cerevisiae) 		3 / 3 PHE D 241
PHE D 236
PHE D 231
 None
 0.64A 2od9A-3k8pD:
undetectable		 2od9A-3k8pD:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1001_0
(ALDEHYDE
DEHYDROGENASE A)		 3k8p PROTEIN TRANSPORT
PROTEIN SEC39
(Saccharomyces
cerevisiae) 		4 / 7 LEU D 385
PHE D 359
ILE D 406
PHE D 367
 None
 0.97A 2opxA-3k8pD:
undetectable		 2opxA-3k8pD:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQG_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 3k8p PROTEIN TRANSPORT
PROTEIN SEC39
(Saccharomyces
cerevisiae) 		3 / 3 PHE D 241
PHE D 236
PHE D 231
 None
 0.64A 2qqgA-3k8pD:
undetectable		 2qqgA-3k8pD:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A27_A_SAMA250_1
(UNCHARACTERIZED
PROTEIN MJ1557)		 3k8p DSL1
PROTEIN TRANSPORT
PROTEIN SEC39
(Kluyveromyces
lactis;
Saccharomyces
cerevisiae) 		3 / 3 MET D 608
GLU C 356
ASN C 477
 None
 0.90A 3a27A-3k8pD:
undetectable		 3a27A-3k8pD:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_A_VDYA6178_1
(VITAMIN D
HYDROXYLASE)		 3k8p DSL1
(Kluyveromyces
lactis) 		5 / 11 THR C 633
ILE C 600
THR C 541
VAL C 522
LEU C 526
 None
 1.02A 3a51A-3k8pC:
1.1		 3a51A-3k8pC:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_C_VDYC6178_1
(VITAMIN D
HYDROXYLASE)		 3k8p DSL1
(Kluyveromyces
lactis) 		5 / 12 THR C 633
ILE C 600
THR C 541
VAL C 522
LEU C 526
 None
 1.02A 3a51C-3k8pC:
1.2		 3a51C-3k8pC:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_D_VDYD6178_1
(VITAMIN D
HYDROXYLASE)		 3k8p DSL1
(Kluyveromyces
lactis) 		5 / 12 THR C 633
ILE C 600
THR C 541
VAL C 522
LEU C 526
 None
 1.05A 3a51D-3k8pC:
undetectable		 3a51D-3k8pC:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_E_VDYE6178_1
(VITAMIN D
HYDROXYLASE)		 3k8p DSL1
(Kluyveromyces
lactis) 		5 / 12 THR C 633
ILE C 600
THR C 541
VAL C 522
LEU C 526
 None
 1.05A 3a51E-3k8pC:
undetectable		 3a51E-3k8pC:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3k8p PROTEIN TRANSPORT
PROTEIN SEC39
(Saccharomyces
cerevisiae) 		5 / 12 PHE D 367
LEU D 411
LEU D 377
LEU D 385
TYR D 381
 None
 1.49A 3adsA-3k8pD:
undetectable		 3adsA-3k8pD:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX94_0
(PROTEIN S100-B)		 3k8p PROTEIN TRANSPORT
PROTEIN SEC39
(Saccharomyces
cerevisiae) 		3 / 3 PHE D 359
CYH D 363
PHE D 376
 None
 0.86A 3cr5X-3k8pD:
undetectable		 3cr5X-3k8pD:
8.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DGQ_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)		 3k8p DSL1
(Kluyveromyces
lactis) 		4 / 5 TYR C 558
ILE C 570
TYR C 618
THR C 617
 None
 1.47A 3dgqA-3k8pC:
undetectable		 3dgqA-3k8pC:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DRC_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 3k8p DSL1
(Kluyveromyces
lactis) 		5 / 12 ILE C 570
ALA C 568
LEU C 557
LEU C 549
ILE C 573
 None
 1.07A 3drcB-3k8pC:
undetectable		 3drcB-3k8pC:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL3_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 3k8p DSL1
(Kluyveromyces
lactis) 		5 / 12 ALA C 634
ILE C 677
ARG C 681
ILE C 660
THR C 633
 None
 1.11A 3ql3A-3k8pC:
undetectable		 3ql3A-3k8pC:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3k8p PROTEIN TRANSPORT
PROTEIN SEC39
(Saccharomyces
cerevisiae) 		3 / 3 LYS D 334
GLU D 330
TRP D 302
 None
 0.60A 3v4tH-3k8pD:
undetectable		 3v4tH-3k8pD:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3k8p PROTEIN TRANSPORT
PROTEIN SEC39
(Saccharomyces
cerevisiae) 		4 / 8 ILE D 197
LEU D 193
VAL D 165
GLY D 164
 None
 0.78A 3w1wA-3k8pD:
undetectable		 3w1wA-3k8pD:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1479_0
(MJ0495-LIKE PROTEIN)		 3k8p PROTEIN TRANSPORT
PROTEIN SEC39
(Saccharomyces
cerevisiae) 		4 / 5 THR D 313
ILE D 314
GLU D 315
PHE D 341
 None
 1.34A 4ac9C-3k8pD:
undetectable		 4ac9C-3k8pD:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3k8p PROTEIN TRANSPORT
PROTEIN SEC39
(Saccharomyces
cerevisiae) 		4 / 5 THR D 313
ILE D 314
GLU D 315
PHE D 341
 None
 1.33A 4acaC-3k8pD:
undetectable		 4acaC-3k8pD:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3k8p PROTEIN TRANSPORT
PROTEIN SEC39
(Saccharomyces
cerevisiae) 		4 / 5 THR D 319
ILE D 314
GLU D 315
PHE D 341
 None
 1.48A 4acaC-3k8pD:
undetectable		 4acaC-3k8pD:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3k8p PROTEIN TRANSPORT
PROTEIN SEC39
(Saccharomyces
cerevisiae) 		4 / 5 THR D 313
ILE D 314
GLU D 315
PHE D 341
 None
 1.30A 4acbC-3k8pD:
undetectable		 4acbC-3k8pD:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3k8p PROTEIN TRANSPORT
PROTEIN SEC39
(Saccharomyces
cerevisiae) 		4 / 5 THR D 319
ILE D 314
GLU D 315
PHE D 341
 None
 1.50A 4acbC-3k8pD:
undetectable		 4acbC-3k8pD:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DM8_A_REAA501_1
(RETINOIC ACID
RECEPTOR BETA)		 3k8p PROTEIN TRANSPORT
PROTEIN SEC39
(Saccharomyces
cerevisiae) 		5 / 11 PHE D 198
LEU D 259
ILE D 232
LEU D 251
ILE D 214
 None
 1.09A 4dm8A-3k8pD:
undetectable		 4dm8A-3k8pD:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HAJ_A_DXCA75_0
(PPCA)		 3k8p PROTEIN TRANSPORT
PROTEIN SEC39
(Saccharomyces
cerevisiae) 		4 / 7 ILE D 182
LYS D 157
LYS D 226
GLY D 225
 None
 0.96A 4hajA-3k8pD:
undetectable		 4hajA-3k8pD:
7.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P66_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 3k8p DSL1
(Kluyveromyces
lactis) 		5 / 11 ILE C 570
ALA C 568
LEU C 557
LEU C 549
ILE C 573
 None
 1.12A 4p66A-3k8pC:
undetectable		 4p66A-3k8pC:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_A_ADNA501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 3k8p PROTEIN TRANSPORT
PROTEIN SEC39
(Saccharomyces
cerevisiae) 		3 / 3 PRO D 525
LEU D 526
HIS D 576
 None
 0.69A 4pevA-3k8pD:
undetectable		 4pevA-3k8pD:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QC6_B_KANB201_2
(BIFUNCTIONAL AAC/APH)		 3k8p PROTEIN TRANSPORT
PROTEIN SEC39
(Saccharomyces
cerevisiae) 		3 / 3 LEU D 575
ASP D 578
TYR D 579
 None
 0.59A 4qc6B-3k8pD:
undetectable		 4qc6B-3k8pD:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_ADNB2415_1
(RNA-DIRECTED RNA
POLYMERASE L)		 3k8p DSL1
(Kluyveromyces
lactis) 		4 / 7 GLU C 356
PHE C 430
LYS C 475
HIS C 360
 None
 1.36A 4uciB-3k8pC:
undetectable		 4uciB-3k8pC:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5J_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3k8p DSL1
(Kluyveromyces
lactis) 		5 / 12 ALA C 634
ILE C 677
ARG C 681
ILE C 660
THR C 633
 None
 1.11A 4x5jA-3k8pC:
undetectable		 4x5jA-3k8pC:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_D_ADND303_1
(5'/3'-NUCLEOTIDASE
SURE)		 3k8p DSL1
(Kluyveromyces
lactis) 		5 / 10 LEU C 545
LEU C 521
SER C 543
ALA C 553
ILE C 518
 None
 1.13A 4xj7C-3k8pC:
undetectable
4xj7D-3k8pC:
undetectable		 4xj7C-3k8pC:
21.49
4xj7D-3k8pC:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3k8p DSL1
(Kluyveromyces
lactis) 		4 / 7 LEU C 511
LEU C 507
THR C 480
THR C 556
 None
 0.70A 4z90A-3k8pC:
4.3
4z90B-3k8pC:
3.1
4z90C-3k8pC:
4.5
4z90D-3k8pC:
4.4
4z90E-3k8pC:
4.4		 4z90A-3k8pC:
21.22
4z90B-3k8pC:
21.22
4z90C-3k8pC:
21.22
4z90D-3k8pC:
21.22
4z90E-3k8pC:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3k8p DSL1
(Kluyveromyces
lactis) 		4 / 8 LEU C 507
THR C 480
THR C 556
LEU C 511
 None
 0.70A 4z90F-3k8pC:
4.3
4z90G-3k8pC:
4.4
4z90H-3k8pC:
4.4
4z90I-3k8pC:
4.5
4z90J-3k8pC:
4.4		 4z90F-3k8pC:
21.22
4z90G-3k8pC:
21.22
4z90H-3k8pC:
21.22
4z90I-3k8pC:
21.22
4z90J-3k8pC:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3k8p DSL1
(Kluyveromyces
lactis) 		4 / 8 THR C 480
THR C 556
LEU C 511
LEU C 507
 None
 0.75A 4z90F-3k8pC:
4.3
4z90G-3k8pC:
4.4
4z90H-3k8pC:
4.4
4z90I-3k8pC:
4.5
4z90J-3k8pC:
4.4		 4z90F-3k8pC:
21.22
4z90G-3k8pC:
21.22
4z90H-3k8pC:
21.22
4z90I-3k8pC:
21.22
4z90J-3k8pC:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E8Q_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3k8p DSL1
(Kluyveromyces
lactis) 		5 / 12 ALA C 634
ILE C 677
ARG C 681
ILE C 660
THR C 633
 None
 1.11A 5e8qA-3k8pC:
undetectable		 5e8qA-3k8pC:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FXT_A_0LAA1376_1
(DNA POLYMERASE III
SUBUNIT BETA)		 3k8p DSL1
PROTEIN TRANSPORT
PROTEIN SEC39
(Kluyveromyces
lactis;
Saccharomyces
cerevisiae) 		4 / 7 LYS C 460
LEU C 463
THR D 663
LEU D 650
 None
 1.04A 5fxtA-3k8pC:
undetectable		 5fxtA-3k8pC:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB308_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3k8p PROTEIN TRANSPORT
PROTEIN SEC39
(Saccharomyces
cerevisiae) 		3 / 3 LEU D 129
ILE D 182
TYR D 224
 None
 0.48A 5uunB-3k8pD:
undetectable		 5uunB-3k8pD:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AZ3_1_PAR11803_1
(RRNA ALPHA
RIBOSOMAL PROTEIN
EL18)		 3k8p DSL1
(Kluyveromyces
lactis) 		3 / 3 SER C 592
LYS C 591
SER C 589
 None
 0.60A 6az3P-3k8pC:
undetectable		 6az3P-3k8pC:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_1
(TUBULIN BETA CHAIN)		 3k8p DSL1
(Kluyveromyces
lactis) 		5 / 12 ALA C 434
PHE C 468
LEU C 499
ARG C 487
LEU C 482
 None
 1.18A 6ew0G-3k8pC:
undetectable		 6ew0G-3k8pC:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_D_ADND502_2
(-)		 3k8p PROTEIN TRANSPORT
PROTEIN SEC39
(Saccharomyces
cerevisiae) 		4 / 5 ILE D 577
GLN D 621
THR D 618
THR D 588
 None
 1.03A 6f3mD-3k8pD:
undetectable		 6f3mD-3k8pD:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FHW_A_ACRA801_2
(GLUCOAMYLASE P)		 3k8p PROTEIN TRANSPORT
PROTEIN SEC39
(Saccharomyces
cerevisiae) 		3 / 3 TRP D 185
GLU D 184
GLU D 192
 None
 0.85A 6fhwA-3k8pD:
5.2		 6fhwA-3k8pD:
7.36