SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3k9c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_A_ADNA601_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 3k9c TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY PROTEIN
(Rhodococcus
jostii) 		5 / 12 ASP A 280
ASP A 169
LEU A  88
GLY A 133
PHE A 251
 GOL  A 349 (-2.8A)
None
None
None
None
 1.18A 1d4fA-3k9cA:
3.2		 1d4fA-3k9cA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 3k9c TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY PROTEIN
(Rhodococcus
jostii) 		5 / 12 ASP A 280
ASP A 169
LEU A  88
GLY A 133
PHE A 251
 GOL  A 349 (-2.8A)
None
None
None
None
 1.16A 1d4fB-3k9cA:
6.4		 1d4fB-3k9cA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_D_ADND604_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 3k9c TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY PROTEIN
(Rhodococcus
jostii) 		5 / 12 ASP A 280
ASP A 169
LEU A  88
GLY A 133
PHE A 251
 GOL  A 349 (-2.8A)
None
None
None
None
 1.20A 1d4fD-3k9cA:
undetectable		 1d4fD-3k9cA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC507_1
(PHOSPHOLIPASE A2)		 3k9c TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY PROTEIN
(Rhodococcus
jostii) 		4 / 7 VAL A 152
VAL A 153
GLY A 133
PRO A 197
 None
 0.92A 3bjwC-3k9cA:
undetectable		 3bjwC-3k9cA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_1
(PHOSPHOLIPASE A2)		 3k9c TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY PROTEIN
(Rhodococcus
jostii) 		4 / 8 VAL A 152
VAL A 153
GLY A 133
PRO A 197
 None
 0.83A 3bjwA-3k9cA:
undetectable		 3bjwA-3k9cA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB2_A_IBPA3960_1
(LACTOTRANSFERRIN)		 3k9c TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY PROTEIN
(Rhodococcus
jostii) 		4 / 4 GLY A 278
VAL A 249
GLY A 224
THR A 223
 None
 0.85A 3ib2A-3k9cA:
undetectable		 3ib2A-3k9cA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROZ_A_NCAA266_0
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 3k9c TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY PROTEIN
(Rhodococcus
jostii) 		4 / 6 LEU A 215
ALA A 247
LEU A 180
THR A 181
 None
 0.98A 3rozA-3k9cA:
3.3		 3rozA-3k9cA:
24.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1W_B_STRB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3k9c TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY PROTEIN
(Rhodococcus
jostii) 		4 / 6 VAL A 103
VAL A  76
ILE A 130
LEU A 311
 None
 0.93A 4l1wB-3k9cA:
undetectable		 4l1wB-3k9cA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3k9c TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY PROTEIN
(Rhodococcus
jostii) 		5 / 12 ASP A 280
ASP A 169
LEU A  88
GLY A 133
PHE A 251
 GOL  A 349 (-2.8A)
None
None
None
None
 1.33A 4pfjB-3k9cA:
4.9		 4pfjB-3k9cA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3k9c TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY PROTEIN
(Rhodococcus
jostii) 		5 / 12 ASP A 280
ASP A 169
LEU A  88
GLY A 133
PHE A 251
 GOL  A 349 (-2.8A)
None
None
None
None
 1.29A 4pgfA-3k9cA:
3.9		 4pgfA-3k9cA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3k9c TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY PROTEIN
(Rhodococcus
jostii) 		5 / 12 ASP A 280
ASP A 169
LEU A  88
GLY A 133
PHE A 251
 GOL  A 349 (-2.8A)
None
None
None
None
 1.36A 4pgfB-3k9cA:
4.2		 4pgfB-3k9cA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2T_A_ACTA108_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 3k9c TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY PROTEIN
(Rhodococcus
jostii) 		3 / 3 VAL A 329
THR A 294
ARG A 331
 None
 0.79A 5b2tB-3k9cA:
2.4		 5b2tB-3k9cA:
11.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_1
(-)		 3k9c TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY PROTEIN
(Rhodococcus
jostii) 		5 / 12 ASP A 280
ASP A 169
LEU A  88
GLY A 133
PHE A 251
 GOL  A 349 (-2.8A)
None
None
None
None
 1.20A 6gbnB-3k9cA:
4.7		 6gbnB-3k9cA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_A_QPSA602_2
(-)		 3k9c TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY PROTEIN
(Rhodococcus
jostii) 		5 / 9 THR A 226
GLY A 225
GLY A 224
HIS A 190
VAL A 221
 None
 1.40A 6gnfA-3k9cA:
3.0		 6gnfA-3k9cA:
19.74