SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3k9h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4007_1
(SERUM ALBUMIN)		 3k9h PF-32 PROTEIN
(Borreliella
burgdorferi) 		4 / 8 LEU A 143
ASP A 136
LEU A 135
LEU A 139
 None
 1.07A 1e7cA-3k9hA:
undetectable		 1e7cA-3k9hA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM4_A_DXCA1001_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 3k9h PF-32 PROTEIN
(Borreliella
burgdorferi) 		5 / 12 PHE A 168
PHE A 169
THR A 131
ILE A 151
SER A 162
 None
 1.47A 1fm4A-3k9hA:
undetectable		 1fm4A-3k9hA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3k9h PF-32 PROTEIN
(Borreliella
burgdorferi) 		5 / 12 LEU A  38
THR A  81
ASP A  79
LEU A 117
GLY A 118
 None
 1.40A 1v8bA-3k9hA:
3.2		 1v8bA-3k9hA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3k9h PF-32 PROTEIN
(Borreliella
burgdorferi) 		5 / 12 LEU A  38
THR A  81
ASP A  79
LEU A 117
GLY A 118
 None
 1.43A 1v8bB-3k9hA:
3.2		 1v8bB-3k9hA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_D_ADND3502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3k9h PF-32 PROTEIN
(Borreliella
burgdorferi) 		5 / 12 LEU A  38
THR A  81
ASP A  79
LEU A 117
GLY A 118
 None
 1.42A 1v8bD-3k9hA:
2.7		 1v8bD-3k9hA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_D_ADND438_1
(ADENOSYLHOMOCYSTEINA
SE)		 3k9h PF-32 PROTEIN
(Borreliella
burgdorferi) 		5 / 12 LEU A  38
THR A  81
ASP A  79
LEU A 117
GLY A 118
 None
 1.30A 3g1uD-3k9hA:
2.9		 3g1uD-3k9hA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_A_D16A530_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3k9h PF-32 PROTEIN
(Borreliella
burgdorferi) 		5 / 12 ALA A  12
ILE A 179
ASP A 164
LEU A 163
PHE A 166
 None
 1.20A 3nrrA-3k9hA:
3.4		 3nrrA-3k9hA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_B_D16B530_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3k9h PF-32 PROTEIN
(Borreliella
burgdorferi) 		5 / 12 ALA A  12
ILE A 179
ASP A 164
LEU A 163
PHE A 166
 None
 1.20A 3nrrB-3k9hA:
undetectable		 3nrrB-3k9hA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7A_B_RGZB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 3k9h PF-32 PROTEIN
(Borreliella
burgdorferi) 		5 / 12 LEU A 120
LEU A 117
LEU A 113
ILE A  92
ILE A 127
 None
 0.99A 4a7aB-3k9hA:
undetectable		 4a7aB-3k9hA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_B_ADNB401_1
(APH(2'')-ID)		 3k9h PF-32 PROTEIN
(Borreliella
burgdorferi) 		4 / 8 SER A 116
ILE A  71
LEU A  38
ILE A  40
 None
 0.85A 4dtaB-3k9hA:
undetectable		 4dtaB-3k9hA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_D_ACTD305_0
(GLUTATHIONE
TRANSFERASE GTE1)		 3k9h PF-32 PROTEIN
(Borreliella
burgdorferi) 		4 / 4 ILE A  71
LEU A  72
LYS A  73
ASN A  67
 None
 0.96A 4g19D-3k9hA:
undetectable		 4g19D-3k9hA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCY_A_DB8A401_2
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 3k9h PF-32 PROTEIN
(Borreliella
burgdorferi) 		4 / 4 VAL A  37
LEU A  27
ASN A  87
ASP A  86
 None
 1.35A 5vcyA-3k9hA:
undetectable		 5vcyA-3k9hA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_E_GBME2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 3k9h PF-32 PROTEIN
(Borreliella
burgdorferi) 		3 / 3 LEU A 173
THR A 131
ASN A 132
 None
 0.45A 6baaE-3k9hA:
undetectable		 6baaE-3k9hA:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_F_GBMF2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 3k9h PF-32 PROTEIN
(Borreliella
burgdorferi) 		3 / 3 LEU A 173
THR A 131
ASN A 132
 None
 0.45A 6baaF-3k9hA:
undetectable		 6baaF-3k9hA:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_G_GBMG2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 3k9h PF-32 PROTEIN
(Borreliella
burgdorferi) 		3 / 3 LEU A 173
THR A 131
ASN A 132
 None
 0.46A 6baaG-3k9hA:
undetectable		 6baaG-3k9hA:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_H_GBMH2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 3k9h PF-32 PROTEIN
(Borreliella
burgdorferi) 		3 / 3 LEU A 173
THR A 131
ASN A 132
 None
 0.46A 6baaH-3k9hA:
2.5		 6baaH-3k9hA:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		 3k9h PF-32 PROTEIN
(Borreliella
burgdorferi) 		4 / 6 LEU A  38
MET A  42
THR A  10
LEU A  31
 None
 0.99A 6mvxA-3k9hA:
undetectable
6mvxB-3k9hA:
undetectable
6mvxC-3k9hA:
undetectable		 6mvxA-3k9hA:
22.44
6mvxB-3k9hA:
22.44
6mvxC-3k9hA:
22.44