SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3k9t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IVV_B_DAHB382_1
(AMINE OXIDASE)		 3k9t PUTATIVE PEPTIDASE
(Clostridium
acetobutylicum) 		5 / 10 TYR A 323
ASP A 297
TYR A 186
HIS A 324
HIS A 189
 None
None
IMD  A 438 (-4.0A)
ZN  A 435 ( 3.2A)
ZN  A 435 ( 3.2A)
 1.32A 1ivvB-3k9tA:
undetectable		 1ivvB-3k9tA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RTS_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 3k9t PUTATIVE PEPTIDASE
(Clostridium
acetobutylicum) 		4 / 8 PHE A 221
ILE A  48
GLY A 169
PHE A 223
 None
MRD  A 441 ( 4.8A)
None
None
 0.86A 1rtsA-3k9tA:
undetectable		 1rtsA-3k9tA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_1
(PROTEASE)		 3k9t PUTATIVE PEPTIDASE
(Clostridium
acetobutylicum) 		5 / 12 LEU A 202
ALA A 207
ILE A 181
ALA A 250
ILE A 203
 None
 0.87A 2nmzA-3k9tA:
undetectable		 2nmzA-3k9tA:
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_C_SAMC300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3k9t PUTATIVE PEPTIDASE
(Clostridium
acetobutylicum) 		4 / 4 SER A  99
GLY A 137
HIS A 189
ASP A 328
 None
None
ZN  A 435 ( 3.2A)
None
 1.35A 2oxtC-3k9tA:
undetectable		 2oxtC-3k9tA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3k9t PUTATIVE PEPTIDASE
(Clostridium
acetobutylicum) 		4 / 6 LEU A  25
ILE A  44
ILE A 173
LEU A 183
 None
 0.98A 2xkwB-3k9tA:
undetectable		 2xkwB-3k9tA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CD2_A_MTXA307_1
(DIHYDROFOLATE
REDUCTASE)		 3k9t PUTATIVE PEPTIDASE
(Clostridium
acetobutylicum) 		5 / 12 ILE A 349
ILE A 173
SER A 218
PRO A  49
ILE A 206
 None
None
None
MRD  A 441 ( 4.9A)
None
 1.01A 3cd2A-3k9tA:
undetectable		 3cd2A-3k9tA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_B_478B200_2
(PROTEASE)		 3k9t PUTATIVE PEPTIDASE
(Clostridium
acetobutylicum) 		5 / 10 LEU A 202
ALA A 207
ILE A 181
ALA A 250
ILE A 203
 None
 0.90A 3ekpB-3k9tA:
undetectable		 3ekpB-3k9tA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_1
(PROTEASE)		 3k9t PUTATIVE PEPTIDASE
(Clostridium
acetobutylicum) 		5 / 10 LEU A 202
ALA A 207
ILE A 181
ALA A 250
ILE A 203
 None
 0.88A 3ekpC-3k9tA:
undetectable		 3ekpC-3k9tA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA278_0
(UNIVERSAL STRESS
PROTEIN)		 3k9t PUTATIVE PEPTIDASE
(Clostridium
acetobutylicum) 		3 / 3 SER A 341
GLY A 337
SER A 198
 None
 0.65A 3loqA-3k9tA:
undetectable		 3loqA-3k9tA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UG8_A_IMNA2001_2
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3k9t PUTATIVE PEPTIDASE
(Clostridium
acetobutylicum) 		3 / 3 TYR A 345
GLU A 353
TYR A 217
 None
 0.99A 3ug8A-3k9tA:
undetectable		 3ug8A-3k9tA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3k9t PUTATIVE PEPTIDASE
(Clostridium
acetobutylicum) 		4 / 8 LEU A 115
VAL A 155
TYR A 153
LEU A 140
 None
 1.06A 3v81A-3k9tA:
undetectable		 3v81A-3k9tA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA304_1
(CHITOSANASE)		 3k9t PUTATIVE PEPTIDASE
(Clostridium
acetobutylicum) 		4 / 4 TYR A 261
ILE A 271
THR A 264
TYR A 409
 None
 1.43A 4oltA-3k9tA:
0.0		 4oltA-3k9tA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB304_1
(CHITOSANASE)		 3k9t PUTATIVE PEPTIDASE
(Clostridium
acetobutylicum) 		4 / 5 TYR A 261
ILE A 271
THR A 264
TYR A 409
 None
 1.47A 4oltB-3k9tA:
undetectable		 4oltB-3k9tA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA303_1
(CHITOSANASE)		 3k9t PUTATIVE PEPTIDASE
(Clostridium
acetobutylicum) 		4 / 6 TYR A 261
ILE A 271
THR A 264
TYR A 409
 None
 1.43A 4qwpA-3k9tA:
undetectable		 4qwpA-3k9tA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB302_1
(CHITOSANASE)		 3k9t PUTATIVE PEPTIDASE
(Clostridium
acetobutylicum) 		4 / 5 TYR A 261
ILE A 271
THR A 264
TYR A 409
 None
 1.41A 4qwpB-3k9tA:
undetectable		 4qwpB-3k9tA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_C_Y70C151_1
(CEREBLON ISOFORM 4)		 3k9t PUTATIVE PEPTIDASE
(Clostridium
acetobutylicum) 		4 / 8 ASN A  92
PRO A 190
PHE A  88
TRP A  70
 None
 1.50A 4v2zC-3k9tA:
undetectable		 4v2zC-3k9tA:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_1
(ESTROGEN RECEPTOR)		 3k9t PUTATIVE PEPTIDASE
(Clostridium
acetobutylicum) 		5 / 12 THR A 251
ALA A 250
LEU A 248
MET A 333
GLY A 337
 None
 1.04A 4xi3C-3k9tA:
undetectable		 4xi3C-3k9tA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H3A_A_D16A401_1
(ORF70)		 3k9t PUTATIVE PEPTIDASE
(Clostridium
acetobutylicum) 		4 / 7 PHE A 221
ILE A  48
GLY A 169
PHE A 223
 None
MRD  A 441 ( 4.8A)
None
None
 0.77A 5h3aA-3k9tA:
undetectable		 5h3aA-3k9tA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H3A_B_D16B401_1
(ORF70)		 3k9t PUTATIVE PEPTIDASE
(Clostridium
acetobutylicum) 		4 / 7 PHE A 221
ILE A  48
GLY A 169
PHE A 223
 None
MRD  A 441 ( 4.8A)
None
None
 0.79A 5h3aB-3k9tA:
undetectable		 5h3aB-3k9tA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_G_ADNG501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3k9t PUTATIVE PEPTIDASE
(Clostridium
acetobutylicum) 		4 / 5 GLU A 353
GLU A 347
THR A 344
LEU A 248
 None
MRD  A 439 ( 4.8A)
None
None
 1.21A 5hm8G-3k9tA:
undetectable		 5hm8G-3k9tA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 3k9t PUTATIVE PEPTIDASE
(Clostridium
acetobutylicum) 		3 / 3 ARG A 372
PRO A 367
ASN A 360
 None
 0.91A 5jwaA-3k9tA:
undetectable
5jwaH-3k9tA:
2.0		 5jwaA-3k9tA:
21.68
5jwaH-3k9tA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 3k9t PUTATIVE PEPTIDASE
(Clostridium
acetobutylicum) 		4 / 7 PHE A 221
ILE A  48
GLY A 169
PHE A 223
 None
MRD  A 441 ( 4.8A)
None
None
 0.81A 5x5qC-3k9tA:
undetectable		 5x5qC-3k9tA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 3k9t PUTATIVE PEPTIDASE
(Clostridium
acetobutylicum) 		4 / 8 PHE A 221
ILE A  48
GLY A 169
PHE A 223
 None
MRD  A 441 ( 4.8A)
None
None
 0.80A 5x5qD-3k9tA:
undetectable		 5x5qD-3k9tA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3k9t PUTATIVE PEPTIDASE
(Clostridium
acetobutylicum) 		4 / 6 HIS A 103
ARG A  78
GLU A 154
TYR A  76
 None
 1.29A 5x7pA-3k9tA:
undetectable		 5x7pA-3k9tA:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3k9t PUTATIVE PEPTIDASE
(Clostridium
acetobutylicum) 		4 / 6 HIS A 103
ARG A  78
GLU A 154
TYR A  76
 None
 1.29A 5x7pB-3k9tA:
undetectable		 5x7pB-3k9tA:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Q_A_ACRA1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3k9t PUTATIVE PEPTIDASE
(Clostridium
acetobutylicum) 		4 / 6 HIS A 103
ARG A  78
GLU A 154
TYR A  76
 None
 1.30A 5x7qA-3k9tA:
undetectable		 5x7qA-3k9tA:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Q_B_ACRB1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3k9t PUTATIVE PEPTIDASE
(Clostridium
acetobutylicum) 		4 / 6 HIS A 103
ARG A  78
GLU A 154
TYR A  76
 None
 1.30A 5x7qB-3k9tA:
undetectable		 5x7qB-3k9tA:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA606_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 3k9t PUTATIVE PEPTIDASE
(Clostridium
acetobutylicum) 		4 / 5 GLU A 226
ASP A 195
HIS A 324
THR A 251
 IMD  A 438 (-2.6A)
ZN  A 435 ( 2.3A)
ZN  A 435 ( 3.2A)
None
 1.20A 6b58A-3k9tA:
undetectable		 6b58A-3k9tA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3k9t PUTATIVE PEPTIDASE
(Clostridium
acetobutylicum) 		3 / 3 ASN A 362
PRO A 367
GLN A 368
 None
 0.78A 6jnhA-3k9tA:
undetectable		 6jnhA-3k9tA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3k9t PUTATIVE PEPTIDASE
(Clostridium
acetobutylicum) 		3 / 3 ASN A 362
PRO A 367
GLN A 368
 None
 0.77A 6jogA-3k9tA:
undetectable		 6jogA-3k9tA:
15.86