SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kae'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1F86_B_T44B528_1
(TRANSTHYRETIN
THR119MET VARIANT)		 3kae POSSIBLE PROTEIN OF
NUCLEAR SCAFFOLD
(Encephalitozoon
cuniculi) 		4 / 4 LYS A  73
LEU A 119
ALA A  81
LEU A  85
 None
 1.31A 1f86B-3kaeA:
undetectable		 1f86B-3kaeA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PIW_A_T3A932_1
(ANDROGEN RECEPTOR)		 3kae POSSIBLE PROTEIN OF
NUCLEAR SCAFFOLD
(Encephalitozoon
cuniculi) 		4 / 6 LEU A  38
VAL A  42
ILE A  13
ILE A   6
 None
 0.87A 2piwA-3kaeA:
undetectable		 2piwA-3kaeA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3kae POSSIBLE PROTEIN OF
NUCLEAR SCAFFOLD
(Encephalitozoon
cuniculi) 		4 / 7 ILE A  82
GLY A 121
LEU A  89
ARG A 139
 None
 0.88A 3elzA-3kaeA:
undetectable		 3elzA-3kaeA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_B_ACRB665_1
(ALPHA-GLUCOSIDASE)		 3kae POSSIBLE PROTEIN OF
NUCLEAR SCAFFOLD
(Encephalitozoon
cuniculi) 		4 / 6 LYS A  76
ASP A  77
TYR A  78
LYS A  80
 None
 1.45A 3pocB-3kaeA:
undetectable		 3pocB-3kaeA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNR_A_6J3A201_0
(TRANSTHYRETIN)		 3kae POSSIBLE PROTEIN OF
NUCLEAR SCAFFOLD
(Encephalitozoon
cuniculi) 		4 / 4 LYS A  73
LEU A 119
ALA A  81
LEU A  85
 None
 1.29A 6gnrA-3kaeA:
undetectable		 6gnrA-3kaeA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNR_B_6J3B201_0
(TRANSTHYRETIN)		 3kae POSSIBLE PROTEIN OF
NUCLEAR SCAFFOLD
(Encephalitozoon
cuniculi) 		4 / 4 LYS A  73
LEU A 119
ALA A  81
LEU A  85
 None
 1.27A 6gnrB-3kaeA:
undetectable		 6gnrB-3kaeA:
17.80