SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kaq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BU5_A_RBFA301_1
(PROTEIN (FLAVODOXIN))		 3kaq FLAVODOXIN
(Desulfovibrio
desulfuricans) 		6 / 7 THR A  12
ASN A  14
TRP A  60
GLY A  94
ASP A  95
TYR A  98
 FMN  A 150 (-3.1A)
FMN  A 150 (-4.0A)
FMN  A 150 (-4.5A)
FMN  A 150 (-3.3A)
None
FMN  A 150 (-3.5A)
 0.54A 1bu5A-3kaqA:
28.3		 1bu5A-3kaqA:
47.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BU5_B_RBFB302_1
(PROTEIN (FLAVODOXIN))		 3kaq FLAVODOXIN
(Desulfovibrio
desulfuricans) 		6 / 8 THR A  12
ASN A  14
TRP A  60
GLY A  94
ASP A  95
TYR A  98
 FMN  A 150 (-3.1A)
FMN  A 150 (-4.0A)
FMN  A 150 (-4.5A)
FMN  A 150 (-3.3A)
None
FMN  A 150 (-3.5A)
 0.48A 1bu5B-3kaqA:
28.3		 1bu5B-3kaqA:
47.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_A_DESA459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3kaq FLAVODOXIN
(Desulfovibrio
desulfuricans) 		5 / 12 LEU A  54
ALA A  19
LEU A  35
VAL A  33
ILE A 108
 None
 1.11A 1s9pA-3kaqA:
undetectable		 1s9pA-3kaqA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7J_A_478A200_1
(POL POLYPROTEIN)		 3kaq FLAVODOXIN
(Desulfovibrio
desulfuricans) 		5 / 11 LEU A  88
GLY A  82
ALA A  47
ASP A  48
VAL A  53
 None
 0.85A 1t7jA-3kaqA:
undetectable		 1t7jA-3kaqA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_A_486A3_1
(GLUCOCORTICOID
RECEPTOR)		 3kaq FLAVODOXIN
(Desulfovibrio
desulfuricans) 		5 / 12 LEU A   7
GLY A  56
VAL A 105
MET A  81
LEU A  83
 None
 1.32A 3h52A-3kaqA:
undetectable		 3h52A-3kaqA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A201_1
(POL POLYPROTEIN)		 3kaq FLAVODOXIN
(Desulfovibrio
desulfuricans) 		5 / 9 LEU A  88
GLY A  82
ALA A  47
ASP A  48
VAL A  53
 None
 0.85A 3u7sA-3kaqA:
undetectable		 3u7sA-3kaqA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD4_C_AOQC4003_1
(CYTOCHROME B)		 3kaq FLAVODOXIN
(Desulfovibrio
desulfuricans) 		5 / 12 GLY A  56
ILE A   6
LEU A  88
LEU A  46
MET A  81
 None
 1.02A 4pd4C-3kaqA:
undetectable		 4pd4C-3kaqA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 3kaq FLAVODOXIN
(Desulfovibrio
desulfuricans) 		5 / 12 GLY A  94
GLU A 127
GLY A 128
SER A  93
ALA A  59
 FMN  A 150 (-3.3A)
None
None
FMN  A 150 (-3.8A)
FMN  A 150 (-3.6A)
 0.82A 4uciA-3kaqA:
undetectable		 4uciA-3kaqA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 3kaq FLAVODOXIN
(Desulfovibrio
desulfuricans) 		5 / 12 GLY A  94
GLU A 127
GLY A 128
SER A  93
ALA A  59
 FMN  A 150 (-3.3A)
None
None
FMN  A 150 (-3.8A)
FMN  A 150 (-3.6A)
 0.83A 4uciB-3kaqA:
undetectable		 4uciB-3kaqA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 3kaq FLAVODOXIN
(Desulfovibrio
desulfuricans) 		5 / 12 GLY A  94
GLU A 127
GLY A 128
SER A  93
ALA A  59
 FMN  A 150 (-3.3A)
None
None
FMN  A 150 (-3.8A)
FMN  A 150 (-3.6A)
 0.84A 4uckA-3kaqA:
undetectable		 4uckA-3kaqA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 3kaq FLAVODOXIN
(Desulfovibrio
desulfuricans) 		4 / 7 VAL A 119
ALA A  89
GLY A 123
ARG A 113
 None
 0.90A 5fpdB-3kaqA:
2.1		 5fpdB-3kaqA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3kaq FLAVODOXIN
(Desulfovibrio
desulfuricans) 		4 / 6 MET A  55
GLY A   9
ALA A  72
LEU A  67
 None
 1.06A 6fosA-3kaqA:
undetectable		 6fosA-3kaqA:
19.05