SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kb3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4H_A_REAA500_1
(NUCLEAR RECEPTOR
ROR-BETA)		 3kb3 PROTEIN PHOSPHATASE
2C 16
(Arabidopsis
thaliana) 		5 / 11 GLN B 475
ILE B 496
ALA B 478
VAL B 498
VAL B 208
 None
 1.26A 1n4hA-3kb3B:
undetectable		 1n4hA-3kb3B:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3kb3 PROTEIN PHOSPHATASE
2C 16
(Arabidopsis
thaliana) 		5 / 12 LEU B 394
LEU B 405
GLY B 401
CYH B 254
ALA B 329
 None
 1.17A 2bm9A-3kb3B:
undetectable		 2bm9A-3kb3B:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3kb3 PROTEIN PHOSPHATASE
2C 16
(Arabidopsis
thaliana) 		5 / 12 LEU B 394
LEU B 405
GLY B 401
CYH B 254
ALA B 329
 None
 1.14A 2bm9B-3kb3B:
undetectable		 2bm9B-3kb3B:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_C_SAMC301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3kb3 PROTEIN PHOSPHATASE
2C 16
(Arabidopsis
thaliana) 		5 / 12 LEU B 394
LEU B 405
GLY B 401
CYH B 254
ALA B 329
 None
 1.14A 2bm9C-3kb3B:
undetectable		 2bm9C-3kb3B:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_C_SAMC301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3kb3 PROTEIN PHOSPHATASE
2C 16
(Arabidopsis
thaliana) 		5 / 12 LEU B 394
LEU B 405
GLY B 401
CYH B 254
ALA B 329
 None
 1.13A 2br4C-3kb3B:
undetectable		 2br4C-3kb3B:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NAI_B_URFB521_1
(RNA DEPENDENT RNA
POLYMERASE)		 3kb3 PROTEIN PHOSPHATASE
2C 16
(Arabidopsis
thaliana) 		4 / 4 ARG B 199
ASP B 243
ASP B 432
ASP B 346
 None
MG  B 997 (-2.7A)
MG  B 997 ( 2.9A)
MG  B 999 (-3.9A)
 1.26A 3naiB-3kb3B:
undetectable		 3naiB-3kb3B:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NAI_C_URFC521_1
(RNA DEPENDENT RNA
POLYMERASE)		 3kb3 PROTEIN PHOSPHATASE
2C 16
(Arabidopsis
thaliana) 		4 / 5 ARG B 199
ASP B 243
ASP B 432
ASP B 346
 None
MG  B 997 (-2.7A)
MG  B 997 ( 2.9A)
MG  B 999 (-3.9A)
 1.22A 3naiC-3kb3B:
0.4		 3naiC-3kb3B:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VLN_A_ACTA908_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 3kb3 PROTEIN PHOSPHATASE
2C 16
(Arabidopsis
thaliana) 		4 / 4 MET B 396
SER B 399
LEU B 394
VAL B 409
 None
 1.46A 3vlnA-3kb3B:
undetectable		 3vlnA-3kb3B:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		 3kb3 PROTEIN PHOSPHATASE
2C 16
(Arabidopsis
thaliana) 		4 / 5 ASP B 402
VAL B 325
GLY B 246
TYR B 404
 None
 1.22A 3w9tA-3kb3B:
undetectable		 3w9tA-3kb3B:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		 3kb3 PROTEIN PHOSPHATASE
2C 16
(Arabidopsis
thaliana) 		4 / 5 ASP B 402
VAL B 325
GLY B 246
TYR B 404
 None
 1.21A 3w9tB-3kb3B:
undetectable		 3w9tB-3kb3B:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		 3kb3 PROTEIN PHOSPHATASE
2C 16
(Arabidopsis
thaliana) 		4 / 5 ASP B 402
VAL B 325
GLY B 246
TYR B 404
 None
 1.21A 3w9tC-3kb3B:
undetectable		 3w9tC-3kb3B:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		 3kb3 PROTEIN PHOSPHATASE
2C 16
(Arabidopsis
thaliana) 		4 / 5 ASP B 402
VAL B 325
GLY B 246
TYR B 404
 None
 1.21A 3w9tD-3kb3B:
undetectable		 3w9tD-3kb3B:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		 3kb3 PROTEIN PHOSPHATASE
2C 16
(Arabidopsis
thaliana) 		4 / 5 ASP B 402
VAL B 325
GLY B 246
TYR B 404
 None
 1.21A 3w9tE-3kb3B:
undetectable		 3w9tE-3kb3B:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		 3kb3 PROTEIN PHOSPHATASE
2C 16
(Arabidopsis
thaliana) 		4 / 5 ASP B 402
VAL B 325
GLY B 246
TYR B 404
 None
 1.21A 3w9tF-3kb3B:
undetectable		 3w9tF-3kb3B:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		 3kb3 PROTEIN PHOSPHATASE
2C 16
(Arabidopsis
thaliana) 		4 / 5 ASP B 402
VAL B 325
GLY B 246
TYR B 404
 None
 1.21A 3w9tG-3kb3B:
undetectable		 3w9tG-3kb3B:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M48_A_21BA704_1
(TRANSPORTER)		 3kb3 PROTEIN PHOSPHATASE
2C 16
(Arabidopsis
thaliana) 		4 / 8 VAL B 297
ASP B 298
SER B 327
ALA B 261
 None
 0.90A 4m48A-3kb3B:
undetectable		 4m48A-3kb3B:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 3kb3 PROTEIN PHOSPHATASE
2C 16
(Arabidopsis
thaliana) 		3 / 3 SER B 399
ALA B 329
VAL B 330
 None
 0.58A 4x1iA-3kb3B:
undetectable		 4x1iA-3kb3B:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XT7_A_TOPA302_1
(RV2671)		 3kb3 PROTEIN PHOSPHATASE
2C 16
(Arabidopsis
thaliana) 		5 / 11 ASN B 343
SER B 397
GLU B 371
GLU B 414
THR B 328
 None
None
None
None
MG  B 999 ( 4.0A)
 1.20A 4xt7A-3kb3B:
undetectable		 4xt7A-3kb3B:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XT8_A_TMQA302_1
(RV2671)		 3kb3 PROTEIN PHOSPHATASE
2C 16
(Arabidopsis
thaliana) 		5 / 12 ASN B 343
SER B 397
GLU B 371
GLU B 414
THR B 328
 None
None
None
None
MG  B 999 ( 4.0A)
 1.27A 4xt8A-3kb3B:
undetectable		 4xt8A-3kb3B:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 3kb3 PROTEIN PHOSPHATASE
2C 16
(Arabidopsis
thaliana) 		3 / 3 SER B 399
ALA B 329
VAL B 330
 None
 0.56A 5eypA-3kb3B:
undetectable		 5eypA-3kb3B:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5C_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 3kb3 PROTEIN PHOSPHATASE
2C 16
(Arabidopsis
thaliana) 		5 / 12 VAL B 330
ALA B 349
SER B 361
GLY B 433
LEU B 434
 None
 1.19A 5m5cB-3kb3B:
undetectable		 5m5cB-3kb3B:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND4_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 3kb3 PROTEIN PHOSPHATASE
2C 16
(Arabidopsis
thaliana) 		5 / 12 VAL B 330
LEU B 427
ALA B 349
SER B 361
LEU B 434
 None
 1.31A 5nd4B-3kb3B:
undetectable		 5nd4B-3kb3B:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3kb3 PROTEIN PHOSPHATASE
2C 16
(Arabidopsis
thaliana) 		4 / 4 LEU B 262
LEU B 333
SER B 342
ALA B 332
 None
 1.04A 5uunA-3kb3B:
undetectable		 5uunA-3kb3B:
25.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CGD_A_AKNA600_1
(BIFUNCTIONAL AAC/APH)		 3kb3 PROTEIN PHOSPHATASE
2C 16
(Arabidopsis
thaliana) 		5 / 10 GLY B 387
ASP B 432
ASP B 436
GLU B 203
GLU B 201
 None
MG  B 997 ( 2.9A)
None
None
None
 1.29A 6cgdA-3kb3B:
undetectable		 6cgdA-3kb3B:
12.54