SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kb5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2503_0
(FERROCHELATASE)		 3kb5 TRIPARTITE
MOTIF-CONTAINING
PROTEIN 72
(Homo
sapiens) 		4 / 4 LEU A 467
PRO A 466
LEU A 468
ARG A 412
 None
 1.45A 1hrkB-3kb5A:
undetectable		 1hrkB-3kb5A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_D_DVAD8_0
(GRAMICIDIN D)		 3kb5 TRIPARTITE
MOTIF-CONTAINING
PROTEIN 72
(Homo
sapiens) 		3 / 3 VAL A 361
VAL A 335
TRP A 347
 None
 0.95A 1w5uC-3kb5A:
undetectable
1w5uD-3kb5A:
undetectable		 1w5uC-3kb5A:
7.74
1w5uD-3kb5A:
7.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_B_SNLB503_2
(MINERALOCORTICOID
RECEPTOR)		 3kb5 TRIPARTITE
MOTIF-CONTAINING
PROTEIN 72
(Homo
sapiens) 		4 / 5 LEU A 424
LEU A 415
LEU A 383
LEU A 382
 None
 1.01A 2ab2B-3kb5A:
undetectable		 2ab2B-3kb5A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1604_0
(FERROCHELATASE)		 3kb5 TRIPARTITE
MOTIF-CONTAINING
PROTEIN 72
(Homo
sapiens) 		4 / 4 LEU A 467
PRO A 466
LEU A 468
ARG A 412
 None
 1.41A 2hrcB-3kb5A:
undetectable		 2hrcB-3kb5A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_B_017B203_1
(PROTEASE)		 3kb5 TRIPARTITE
MOTIF-CONTAINING
PROTEIN 72
(Homo
sapiens) 		4 / 6 PRO A 446
LEU A 424
ARG A 447
GLY A 343
 None
 1.21A 2hs2B-3kb5A:
undetectable		 2hs2B-3kb5A:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA8_0
(GRAMICIDIN D)		 3kb5 TRIPARTITE
MOTIF-CONTAINING
PROTEIN 72
(Homo
sapiens) 		3 / 3 VAL A 335
TRP A 347
VAL A 361
 None
 0.93A 2izqA-3kb5A:
undetectable
2izqB-3kb5A:
undetectable		 2izqA-3kb5A:
7.74
2izqB-3kb5A:
7.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA508_0
(CHORISMATE SYNTHASE)		 3kb5 TRIPARTITE
MOTIF-CONTAINING
PROTEIN 72
(Homo
sapiens) 		4 / 5 LEU A 382
ASP A 454
ALA A 358
ILE A 362
 None
 1.18A 2qhfA-3kb5A:
undetectable		 2qhfA-3kb5A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3kb5 TRIPARTITE
MOTIF-CONTAINING
PROTEIN 72
(Homo
sapiens) 		5 / 12 TYR A 346
VAL A 349
GLY A 414
PHE A 426
LEU A 424
 None
 1.10A 3em0B-3kb5A:
undetectable		 3em0B-3kb5A:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS4_A_AZMA702_1
(CARBONIC ANHYDRASE 2)		 3kb5 TRIPARTITE
MOTIF-CONTAINING
PROTEIN 72
(Homo
sapiens) 		4 / 7 VAL A 375
LYS A 398
GLU A 399
PRO A 400
 None
 1.27A 3hs4A-3kb5A:
undetectable		 3hs4A-3kb5A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD8_0
(GRAMICIDIN D)		 3kb5 TRIPARTITE
MOTIF-CONTAINING
PROTEIN 72
(Homo
sapiens) 		3 / 3 VAL A 361
VAL A 335
TRP A 347
 None
 0.96A 3l8lC-3kb5A:
undetectable
3l8lD-3kb5A:
undetectable		 3l8lC-3kb5A:
7.74
3l8lD-3kb5A:
10.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_A_STRA604_1
(CYTOCHROME P450
21-HYDROXYLASE)		 3kb5 TRIPARTITE
MOTIF-CONTAINING
PROTEIN 72
(Homo
sapiens) 		5 / 12 SER A 430
LEU A 359
ASP A 428
GLY A 414
VAL A 470
 None
 1.01A 4y8wA-3kb5A:
undetectable		 4y8wA-3kb5A:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_A_ZITA501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)		 3kb5 TRIPARTITE
MOTIF-CONTAINING
PROTEIN 72
(Homo
sapiens) 		4 / 7 ALA A 429
GLY A 414
TYR A 427
TYR A 416
 None
 1.04A 5uxdA-3kb5A:
undetectable		 5uxdA-3kb5A:
20.78